Search Results - "Teobald, Barry J"

From ATP to AZD6140 : The discovery of an orally active reversible P2Y12 receptor antagonist for the prevention of thrombosis by SPRINGTHORPE, Brian, BAILEY, Andrew, HUNT, Simon F, INCE, Francis, INGALL, Anthony H, KIRK, Ian P, LEESON, Paul D, LEFF, Paul, LEWIS, Richard J, MARTIN, Barrie P, MCGINNITY, Dermot F, MORTIMORE, Michael P, BARTON, Patrick, PAINE, Stuart W, PAIRAUDEAU, Garry, PATEL, Anil, RIGBY, Aaron J, RILEY, Robert J, TEOBALD, Barry J, TOMLINSON, Wendy, WEBBORN, Peter J. H, WILLIS, Paul A, BIRKINSHAW, Timothy N, BONNERT, Roger V, BROWN, Roger C, CHAPMAN, David, DIXON, John, GUILE, Simon D, HUMPHRIES, Robert G

“…Starting from adenosine triphosphate (ATP), the identification of a novel series of P2Y(12) receptor antagonists and exploitation of their SAR is described…”
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The use of temporary tethers in the meta photocycloaddition reaction by Penkett, Clive S, Byrne, Paul W, Teobald, Barry J, Rola, Benedicte, Ozanne, Aurelie, Hitchcock, Peter B

“…The use of temporary tethers in facilitating meta photocycloaddition reactions between phenol and allyl alcohol derivatives has been investigated. The merits…”
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The Nicholas reaction: the use of dicobalt hexacarbonyl-stabilised propargylic cations in synthesis by Teobald, Barry J.

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Antagonists of the Platelet P 2T Receptor:  A Novel Approach to Antithrombotic Therapy by Ingall, Anthony H, Dixon, John, Bailey, Andrew, Coombs, Mandy E, Cox, David, McInally, Judith I, Hunt, Simon F, Kindon, Nicholas D, Teobald, Barry J, Willis, Paul A, Humphries, Robert G, Leff, Paul, Clegg, Jane A, Smith, James A, Tomlinson, Wendy

“…The platelet P 2T receptor plays a major role in platelet aggregation, and its antagonists are predicted to have significant therapeutic potential as…”
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Antagonists of the Platelet P2T Receptor:  A Novel Approach to Antithrombotic Therapy by INGALL, Anthony H., DIXON, John, BAILEY, Andrew, COOMBS, Mandy E., COX, David, MCINALLY, Judith I., HUNT, Simon F., KINDON, Nicholas D., TEOBALD, Barry J., WILLIS, Paul A., HUMPHRIES, Robert G., LEFF, Paul, CLEGG, Jane A., SMITH, James A., TOMLINSON, Wendy

“…The platelet P2T receptor plays a major role in platelet aggregation, and its antagonists are predicted to have significant therapeutic potential as…”
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From ATP to AZD6140: The discovery of an orally active reversible P2Y 12 receptor antagonist for the prevention of thrombosis by Springthorpe, Brian, Bailey, Andrew, Barton, Patrick, Birkinshaw, Timothy N., Bonnert, Roger V., Brown, Roger C., Chapman, David, Dixon, John, Guile, Simon D., Humphries, Robert G., Hunt, Simon F., Ince, Francis, Ingall, Anthony H., Kirk, Ian P., Leeson, Paul D., Leff, Paul, Lewis, Richard J., Martin, Barrie P., McGinnity, Dermot F., Mortimore, Michael P., Paine, Stuart W., Pairaudeau, Garry, Patel, Anil, Rigby, Aaron J., Riley, Robert J., Teobald, Barry J., Tomlinson, Wendy, Webborn, Peter J.H., Willis, Paul A.

“…Starting with ATP, the identification of novel P2Y 12 receptor antagonists are described. The leading compound, 17 (AZD6140), is currently in a phase III…”
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