Search Results - "Teo, S.M."

Recurrent Fusion Genes in Gastric Cancer: CLDN18-ARHGAP26 Induces Loss of Epithelial Integrity by Yao, Fei, Kausalya, Jaya P., Sia, Yee Yen, Teo, Audrey S.M., Lee, Wah Heng, Ong, Alicia G.M., Zhang, Zhenshui, Tan, Joanna H.J., Li, Guoliang, Bertrand, Denis, Liu, Xingliang, Poh, Huay Mei, Guan, Peiyong, Zhu, Feng, Pathiraja, Thushangi Nadeera, Ariyaratne, Pramila N., Rao, Jaideepraj, Woo, Xing Yi, Cai, Shaojiang, Mulawadi, Fabianus H., Poh, Wan Ting, Veeravalli, Lavanya, Chan, Chee Seng, Lim, Seong Soo, Leong, See Ting, Neo, Say Chuan, Choi, Poh Sum D., Chew, Elaine G.Y., Nagarajan, Niranjan, Jacques, Pierre-Étienne, So, Jimmy B.Y., Ruan, Xiaoan, Yeoh, Khay Guan, Tan, Patrick, Sung, Wing-Kin, Hunziker, Walter, Ruan, Yijun, Hillmer, Axel M.

“…Genome rearrangements, a hallmark of cancer, can result in gene fusions with oncogenic properties. Using DNA paired-end-tag (DNA-PET) whole-genome sequencing,…”
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TP53 intron 1 hotspot rearrangements are specific to sporadic osteosarcoma and can cause Li-Fraumeni syndrome by Ribi, Sebastian, Baumhoer, Daniel, Lee, Kristy, Edison, Teo, Audrey S M, Madan, Babita, Zhang, Kang, Kohlmann, Wendy K, Yao, Fei, Lee, Wah Heng, Hoi, Qiangze, Cai, Shaojiang, Woo, Xing Yi, Tan, Patrick, Jundt, Gernot, Smida, Jan, Nathrath, Michaela, Sung, Wing-Kin, Schiffman, Joshua D, Virshup, David M, Hillmer, Axel M

“…Somatic mutations of TP53 are among the most common in cancer and germline mutations of TP53 (usually missense) can cause Li-Fraumeni syndrome (LFS). Recently,…”
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Molecular insights into evolution, mutations and receptor-binding specificity of influenza A and B viruses from outpatients and hospitalized patients in Singapore by Ivan, Fransiskus X., Zhou, Xinrui, Lau, Suk Hiang, Rashid, Shamima, Teo, Jasmine S.M., Lee, Hong Kai, Koay, Evelyn S., Chan, Kwai Peng, Leo, Yee Sin, Chen, Mark I.C., Kwoh, Chee Keong, Chow, Vincent T.

“…•Singapore influenza A and B virus strains from 2012-2015 are mainly part of the global influenza virus circulation and evolution.•Several amino acid sites…”
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Elucidating the genomic architecture of Asian EGFR-mutant lung adenocarcinoma through multi-region exome sequencing by Nahar, Rahul, Zhai, Weiwei, Zhang, Tong, Takano, Angela, Khng, Alexis J., Lee, Yin Yeng, Liu, Xingliang, Lim, Chong Hee, Koh, Tina P. T., Aung, Zaw Win, Lim, Tony Kiat Hon, Veeravalli, Lavanya, Yuan, Ju, Teo, Audrey S. M., Chan, Cheryl X., Poh, Huay Mei, Chua, Ivan M. L., Liew, Audrey Ann, Lau, Dawn Ping Xi, Kwang, Xue Lin, Toh, Chee Keong, Lim, Wan-Teck, Lim, Bing, Tam, Wai Leong, Tan, Eng-Huat, Hillmer, Axel M., Tan, Daniel S. W.

“…EGFR -mutant lung adenocarcinomas (LUAD) display diverse clinical trajectories and are characterized by rapid but short-lived responses to EGFR tyrosine kinase…”
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A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer by Ng, King Pan, Hillmer, Axel M, Chuah, Charles T H, Juan, Wen Chun, Ko, Tun Kiat, Teo, Audrey S M, Ariyaratne, Pramila N, Takahashi, Naoto, Sawada, Kenichi, Fei, Yao, Soh, Sheila, Lee, Wah Heng, Huang, John W J, Allen, John C, Woo, Xing Yi, Nagarajan, Niranjan, Kumar, Vikrant, Thalamuthu, Anbupalam, Poh, Wan Ting, Ang, Ai Leen, Mya, Hae Tha, How, Gee Fung, Yang, Li Yi, Koh, Liang Piu, Chowbay, Balram, Chang, Chia-Tien, Nadarajan, Veera S, Chng, Wee Joo, Than, Hein, Lim, Lay Cheng, Goh, Yeow Tee, Zhang, Shenli, Poh, Dianne, Tan, Patrick, Seet, Ju-Ee, Ang, Mei-Kim, Chau, Noan-Minh, Ng, Quan-Sing, Tan, Daniel S W, Soda, Manabu, Isobe, Kazutoshi, Nöthen, Markus M, Wong, Tien Y, Shahab, Atif, Ruan, Xiaoan, Cacheux-Rataboul, Valère, Sung, Wing-Kin, Tan, Eng Huat, Yatabe, Yasushi, Mano, Hiroyuki, Soo, Ross A, Chin, Tan Min, Lim, Wan-Teck, Ruan, Yijun, Ong, S Tiong

“…Intrinsic resistance to tyrosine kinase inhibitor (TKI) drugs is limiting the progress of targeted cancer therapies. The efficacy of TKIs relies on their…”
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An integrative model of pathway convergence in genetically heterogeneous blast crisis chronic myeloid leukemia by Ko, Tun Kiat, Javed, Asif, Lee, Kian Leong, Pathiraja, Thushangi N., Liu, Xingliang, Malik, Simeen, Soh, Sheila Xinxuan, Heng, Xiu Ting, Takahashi, Naoto, Tan, Joanna H.J., Bhatia, Ravi, Khng, Alexis J., Chng, Wee-Joo, Sia, Yee Yen, Fruman, David A., Ng, King Pan, Chan, Zhu En, Xie, Kim Jiajing, Hoi, Qiangze, Chan, Cheryl Xueli, Teo, Audrey S.M., Velazquez Camacho, Oscar, Meah, Wee Yang, Khor, Chiea Chuen, Ong, Chin Thing J., Soon, Wei Jia W., Tan, Patrick, Ng, Pauline C., Chuah, Charles, Hillmer, Axel M., Ong, S. Tiong

“…Targeted therapies against the BCR-ABL1 kinase have revolutionized treatment of chronic phase (CP) chronic myeloid leukemia (CML). In contrast, management of…”
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Integrative Profiling of T790M-Negative EGFR-Mutated NSCLC Reveals Pervasive Lineage Transition and Therapeutic Opportunities by Chua, Khi Pin, Teng, Yvonne H F, Tan, Aaron C, Takano, Angela, Alvarez, Jacob J S, Nahar, Rahul, Rohatgi, Neha, Lai, Gillianne G Y, Aung, Zaw Win, Yeong, Joe P S, Lim, Kiat Hon, Naeini, Marjan Mojtabavi, Kassam, Irfahan, Jain, Amit, Tan, Wan Ling, Gogna, Apoorva, Too, Chow Wei, Kanesvaran, Ravindran, Ng, Quan Sing, Ang, Mei Kim, Rajasekaran, Tanujaa, Anantham, Devanand, Phua, Ghee Chee, Tan, Bien Soo, Lee, Yin Yeng, Wang, Lanying, Teo, Audrey S M, Khng, Alexis Jiaying, Lim, Ming Jie, Suteja, Lisda, Toh, Chee Keong, Lim, Wan-Teck, Iyer, N Gopalakrishna, Tam, Wai Leong, Tan, Eng-Huat, Zhai, Weiwei, Hillmer, Axel M, Skanderup, Anders J, Tan, Daniel S W

“…Despite the established role of EGFR tyrosine kinase inhibitors (TKIs) in -mutated NSCLC, drug resistance inevitably ensues, with a paucity of treatment…”
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Priapism mimic: penile metastasis from hepatocellular carcinoma by Gatsinga, Rene, Tan, Yu Guang, Ngo, Nye Thane, Teo, Jonathan Sm

“…We describe the case of a metastatic penile tumour of hepatocellular origin treated with surgical resection…”
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Perioperative anticoagulation and open distal corpora cavernosa shunt in the management of a case of stuttering idiopathic persistent childhood ischaemic priapism by Teo, Jonathan S.M., Lee, Han Jie, Yuen, John S.P.

“…Childhood priapism is a rare entity and there is currently no consensus regarding its contemporary management. The use of perioperative anticoagulation and…”
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The role of intravesical prostatic protrusion (IPP) in the evaluation and treatment of bladder outlet obstruction (BOO) by Kuo, Tricia L.C., Teo, Jonathan S.M., Foo, K.T.

“…Aims Intravesical prostatic protrusion (IPP) may be an underutilized modality for the assessment of bladder outlet obstruction (BOO). Pressure flow studies or…”
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Whole-genome sequencing of asian lung cancers: second-hand smoke unlikely to be responsible for higher incidence of lung cancer among Asian never-smokers by Krishnan, Vidhya G, Ebert, Philip J, Ting, Jason C, Lim, Elaine, Wong, Swee-Seong, Teo, Audrey S M, Yue, Yong G, Chua, Hui-Hoon, Ma, Xiwen, Loh, Gary S L, Lin, Yuhao, Tan, Joanna H J, Yu, Kun, Zhang, Shenli, Reinhard, Christoph, Tan, Daniel S W, Peters, Brock A, Lincoln, Stephen E, Ballinger, Dennis G, Laramie, Jason M, Nilsen, Geoffrey B, Barber, Thomas D, Tan, Patrick, Hillmer, Axel M, Ng, Pauline C

“…Asian nonsmoking populations have a higher incidence of lung cancer compared with their European counterparts. There is a long-standing hypothesis that the…”
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Detection of chromosomal breakpoints in patients with developmental delay and speech disorders by Utami, Kagistia H, Hillmer, Axel M, Aksoy, Irene, Chew, Elaine G Y, Teo, Audrey S M, Zhang, Zhenshui, Lee, Charlie W H, Chen, Pauline J, Seng, Chan Chee, Ariyaratne, Pramila N, Rouam, Sigrid L, Soo, Lim Seong, Yousoof, Saira, Prokudin, Ivan, Peters, Gregory, Collins, Felicity, Wilson, Meredith, Kakakios, Alyson, Haddad, Georges, Menuet, Arnaud, Perche, Olivier, Tay, Stacey Kiat Hong, Sung, Ken W K, Ruan, Xiaoan, Ruan, Yijun, Liu, Edison T, Briault, Sylvain, Jamieson, Robyn V, Davila, Sonia, Cacheux, Valere

“…Delineating candidate genes at the chromosomal breakpoint regions in the apparently balanced chromosome rearrangements (ABCR) has been shown to be more…”
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Systems consequences of amplicon formation in human breast cancer by Inaki, Koichiro, Menghi, Francesca, Woo, Xing Yi, Wagner, Joel P, Jacques, Pierre-Étienne, Lee, Yi Fang, Shreckengast, Phung Trang, Soon, Wendy WeiJia, Malhotra, Ankit, Teo, Audrey S M, Hillmer, Axel M, Khng, Alexis Jiaying, Ruan, Xiaoan, Ong, Swee Hoe, Bertrand, Denis, Nagarajan, Niranjan, Karuturi, R Krishna Murthy, Miranda, Alfredo Hidalgo, Liu, Edison T

“…Chromosomal structural variations play an important role in determining the transcriptional landscape of human breast cancers. To assess the nature of these…”
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Comprehensive long-span paired-end-tag mapping reveals characteristic patterns of structural variations in epithelial cancer genomes by Hillmer, Axel M, Yao, Fei, Inaki, Koichiro, Lee, Wah Heng, Ariyaratne, Pramila N, Teo, Audrey S M, Woo, Xing Yi, Zhang, Zhenshui, Zhao, Hao, Ukil, Leena, Chen, Jieqi P, Zhu, Feng, So, Jimmy B Y, Salto-Tellez, Manuel, Poh, Wan Ting, Zawack, Kelson F B, Nagarajan, Niranjan, Gao, Song, Li, Guoliang, Kumar, Vikrant, Lim, Hui Ping J, Sia, Yee Yen, Chan, Chee Seng, Leong, See Ting, Neo, Say Chuan, Choi, Poh Sum D, Thoreau, Hervé, Tan, Patrick B O, Shahab, Atif, Ruan, Xiaoan, Bergh, Jonas, Hall, Per, Cacheux-Rataboul, Valère, Wei, Chia-Lin, Yeoh, Khay Guan, Sung, Wing-Kin, Bourque, Guillaume, Liu, Edison T, Ruan, Yijun

“…Somatic genome rearrangements are thought to play important roles in cancer development. We optimized a long-span paired-end-tag (PET) sequencing approach…”
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Comparison of patient survival between various subgroups among renal transplant patients: A single center experience by Go, K.W., Teo, S.M.

“…To compare patient graft survival between various subgroups among renal transplant patients. A retrospective analysis of all renal transplant patients from…”
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Functional Analysis of the CML Blast Crisis Transcriptome and Epigenome Using Crispr-CAS9 and Pharmacologic Approaches by Ko, Tun Kiat, Soh, Xin Xuan Sheila, Yu, Willie, Winter, Peter S., Pathiraja, Thushangi, Javed, Asif, Malik, Simeen, Tan, Joanna H.J., Chuah, Charles, Takahashi, Naoto, Bhatia, Ravi, Chng, Wee Joo, Valent, Peter, Cerny-Reiterer, Sabine, Ng, King Pan, Tennakoon, Chandana, Hoi, Qiangze, Guan, Peiyong, Teo, Audrey S.M., Lee, Wah Heng, Tan, Patrick, Sung, Win Kin, Ng, Pauline, Hillmer, Axel, Wood, Kris C., Rozen, Steve, Ong, S. Tiong

“…Current models of CML blast crisis (BC) propose that expression of BCR-ABL results in genomic instability and the acquisition of genetic alterations that…”
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The Genomic and Epigenomic Landscapes of Blast Crisis Transformation in Chronic Myeloid Leukemia by Ong, S. Tiong, Pathiraja, Thushangi, Javed, Asif, Soh, Xin Xuan Sheila, Malik, Simeen, Tan, Joanna H.J., Ko, Tun Kiat, Chuah, Charles, Takahashi, Naoto, Bhatia, Ravi, Ng, King Pan, Chng, Wee Joo, Tennakoon, Chandana, Hoi, Qiangze, Guan, Peiyong, Teo, Audrey S.M., Lee, Wah Heng, Tan, Patrick, Sung, Win Kin, Ng, Pauline, Hillmer, Axel

“…The transition from chronic phase (CP) to blast crisis (BC) chronic myeloid leukemia (CML) is characterized by reprogramming of the CML transcriptome (Radich…”
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Abstract A1-25: Intratumor heterogeneity in never-smoker Asian EGFR mutant lung adenocarcinoma by Nahar, Rahul, Zhai, Weiwei, Takano, Angela, Khng, Alexis Jiaying, Liu, Xingliang, Lim, Chong Hee, Teo, Audrey S.M., Chan, Cheryl Xueli, Gogna, Apoorva, Lim, Kiat-Hon, Koh, Tina, Poh, Huay Mei, Lee, Yin Yeng, Chen, Liang He, Zhang, Tong, Krishnan, Vidhya Gomathi, Iyer, N Gopalakrishna, Ng, Pauline, Lim, Wan Teck, Lim, Bing, Tan, Eng-Huat, Tan, Daniel S.W., Hillmer, Axel M.

“…Abstract Lung cancer has the highest cancer associated mortality rate in many countries across the world. In contrast to western populations, approximately…”
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Abstract B2-54: Intratumor heterogeneity in never-smoker Asian EGFR mutant lung adenocarcinoma by Nahar, Rahul, Zhai, Weiwei, Takano, Angela, Khng, Alexis Jiaying, Liu, Xingliang, Lim, Chong Hee, Teo, Audrey S.M., Chan, Cheryl Xueli, Gogna, Apoorva, Lim, Kiat-Hon, Koh, Tina, Poh, Huay Mei, Lee, Yin Yeng, Chen, Liang He, Zhang, Tong, Krishnan, Vidhya Gomathi, Iyer, N Gopalakrishna, Ng, Pauline, Lim, Wan Teck, Lim, Bing, Tan, Eng-Huat, Tan, Daniel S.W., Hillmer, Axel M.

“…Abstract Lung cancer has the highest cancer associated mortality rate in many countries across the world. In contrast to western populations, approximately…”
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Familial hypomagnesemia with hypercalciuria and nephrocalcinosis: variable phenotypic expression in three affected sisters from Mexican ancestry by Arteaga, María E, Hunziker, Walter, Teo, Audrey S M, Hillmer, Axel M, Mutchinick, Osvaldo M

“…Familial hypomagnesemia with hypercalciuria and nephrocalcinosis is a rare autosomal recessive renal disease caused by mutations in genes for the tight…”
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