Search Results - "Tenuta, Mary"
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Vaccine elicitation of HIV broadly neutralizing antibodies from engineered B cells
Published in Nature communications (17-11-2020)“…HIV broadly neutralizing antibodies (bnAbs) can suppress viremia and protect against HIV infection. However, their elicitation is made difficult by low…”
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Author Correction: Vaccine elicitation of HIV broadly neutralizing antibodies from engineered B cells
Published in Nature communications (07-12-2020)“…A Correction to this paper has been published: https://doi.org/10.1038/s41467-020-20304-y…”
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In vivo engineered B cells secrete high titers of broadly neutralizing anti-HIV antibodies in mice
Published in Nature biotechnology (01-08-2022)“…Transplantation of B cells engineered ex vivo to secrete broadly neutralizing antibodies (bNAbs) has shown efficacy in disease models. However, clinical…”
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In-vivo engineering of B cells elicits memory retention and allows for secretion of broadly neutralizing antibodies in mice
Published in The Journal of immunology (1950) (01-05-2021)“…Abstract A potential single-shot HIV therapy may be transplanted engineered B cells allowing strong secretion of broadly neutralizing antibodies (bNAbs)…”
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