Search Results - "Tenhagen, M"

  • Showing 1 - 15 results of 15
Refine Results
  1. 1

    RasGRP1 overexpression in T-ALL increases basal nucleotide exchange on Ras rendering the Ras/PI3K/Akt pathway responsive to protumorigenic cytokines by Ksionda, O, Melton, A A, Bache, J, Tenhagen, M, Bakker, J, Harvey, R, Winter, S S, Rubio, I, Roose, J P

    Published in Oncogene (14-07-2016)
    “…Ras GTPases are activated by RasGEFs and inactivated by RasGAPs, which stimulate the hydrolysis of RasGTP to inactive RasGDP. GTPase-impairing somatic…”
    Get full text
    Journal Article
  2. 2

    Restraining FOXO3-dependent transcriptional BMF activation underpins tumour growth and metastasis of E-cadherin-negative breast cancer by Hornsveld, M, Tenhagen, M, van de Ven, R A, Smits, A M M, van Triest, M H, van Amersfoort, M, Kloet, D E A, Dansen, T B, Burgering, B M, Derksen, P W B

    Published in Cell death and differentiation (01-09-2016)
    “…Loss of cellular adhesion leads to the progression of breast cancer through acquisition of anchorage independence, also known as resistance to anoikis…”
    Get full text
    Journal Article
  3. 3

    Fibroblast growth factor receptors in breast cancer: expression, downstream effects, and possible drug targets by Tenhagen, M, van Diest, P J, Ivanova, I A, van der Wall, E, van der Groep, P

    Published in Endocrine-related cancer (01-08-2012)
    “…Cancer treatments are increasingly focusing on the molecular mechanisms underlying the oncogenic processes present in tumors of individual patients. Fibroblast…”
    Get full text
    Journal Article
  4. 4

    Required distal mesorectal resection margin in partial mesorectal excision: a systematic review on distal mesorectal spread by Grüter, A. A. J., van Lieshout, A. S., van Oostendorp, S. E., Ket, J. C. F., Tenhagen, M., den Boer, F. C., Hompes, R., Tanis, P. J., Tuynman, J. B.

    Published in Techniques in coloproctology (01-01-2023)
    “…Background The required distal margin in partial mesorectal excision (PME) is controversial. The aim of this systematic review was to determine incidence and…”
    Get full text
    Journal Article
  5. 5
  6. 6
  7. 7

    Use of ileostomy versus colostomy as a bridge to surgery in left-sided obstructive colon cancer: retrospective cohort study by Smalbroek, Bo P, Weijs, Teus J, Dijksman, Lea M, Poelmann, Floris B, Goense, Lucas, Dijkstra, Robert R, Wijffels, Niels A T, Boerma, Djamila, Smits, Anke B

    Published in BJS open (05-05-2023)
    “…Abstract Background Colorectal cancer causes the majority of large bowel obstructions and surgical resection remains the gold standard for curative treatment…”
    Get full text
    Journal Article
  8. 8
  9. 9

    A painful right knee after a motorcycle accident by Sanders, F R K, Tenhagen, M, Bloemers, F W

    “…A 48-year-old male presented with a painful right knee after a motorcycle accident. Peripheral pulsations in the lower right leg were absent. X-ray indicated a…”
    Get more information
    Journal Article
  10. 10
  11. 11

    Mesenteric venous thrombosis during pregnancy; a rare cause of acute ischaemia of the small intestine by Reiber, B M M, Gorter, R R, Tenhagen, M, Cense, H A, Demirkiran, A

    “…Acute ischaemia of the small intestine is caused by mesenteric venous thrombosis in 5-15% of patients. The non-specific symptoms frequently lead to a…”
    Get more information
    Journal Article
  12. 12

    A scoring system to predict the severity of appendicitis in children by Gorter, Ramon R., MD, van den Boom, Anne Loes, MD, Heij, Hugo A., MD, PhD, Kneepkens, C.M. Frank, MD, PhD, Hulsker, Caroline C., MD, Tenhagen, Mark, MD, Dawson, Imro, MD, PhD, van der Lee, Johanna H., MD, PhD

    Published in The Journal of surgical research (01-02-2016)
    “…Abstract Background It appears that two forms of appendicitis exist. Preoperative distinction between the two is essential to optimize treatment outcome. This…”
    Get full text
    Journal Article
  13. 13
  14. 14

    The stable bacteriocin release protein signal peptide, expressed as a separate entity, functions in the release of cloacin DF13 by van der Wal, F J, ten Hagen, C M, Oudega, B, Luirink, J

    Published in FEMS microbiology letters (01-09-1995)
    “…The pCloDF13 encoded bacteriocin release protein (BRP) plays a role in the release of the bacteriocin cloacin DF13. The BRP signal peptide is stable after…”
    Get more information
    Journal Article
  15. 15

    Application of the PCLODF13 bacteriocin release protein in the release of heterologous proteins by Escherichia coli : production of plant α-galactosidase by VAN DER WAL, F. J, TEN HAGEN, C. M, OUDEGA, B, LUIRINK, J

    Published in Biotechnology letters (01-08-1995)
    “…The bacteriocin release protein (BRP) mediated release of several eukaryotic proteins was studied in Escherichia coli. The genes for the plant proteins alpha…”
    Get full text
    Journal Article