Search Results - "Tenhagen, M"
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RasGRP1 overexpression in T-ALL increases basal nucleotide exchange on Ras rendering the Ras/PI3K/Akt pathway responsive to protumorigenic cytokines
Published in Oncogene (14-07-2016)“…Ras GTPases are activated by RasGEFs and inactivated by RasGAPs, which stimulate the hydrolysis of RasGTP to inactive RasGDP. GTPase-impairing somatic…”
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Restraining FOXO3-dependent transcriptional BMF activation underpins tumour growth and metastasis of E-cadherin-negative breast cancer
Published in Cell death and differentiation (01-09-2016)“…Loss of cellular adhesion leads to the progression of breast cancer through acquisition of anchorage independence, also known as resistance to anoikis…”
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Fibroblast growth factor receptors in breast cancer: expression, downstream effects, and possible drug targets
Published in Endocrine-related cancer (01-08-2012)“…Cancer treatments are increasingly focusing on the molecular mechanisms underlying the oncogenic processes present in tumors of individual patients. Fibroblast…”
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Required distal mesorectal resection margin in partial mesorectal excision: a systematic review on distal mesorectal spread
Published in Techniques in coloproctology (01-01-2023)“…Background The required distal margin in partial mesorectal excision (PME) is controversial. The aim of this systematic review was to determine incidence and…”
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Clinical appearance and management of massive localized lymphedema in morbidly obese patients: report of 2 cases
Published in Updates in surgery (01-03-2014)Get full text
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Perioperative management of obstructive sleep apnea in bariatric surgery: a consensus guideline
Published in Surgery for obesity and related diseases (01-07-2017)“…Abstract Background The frequency of metabolic and bariatric surgery (MBS) is increasing worldwide, with over 500,000 cases performed every year. Obstructive…”
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Use of ileostomy versus colostomy as a bridge to surgery in left-sided obstructive colon cancer: retrospective cohort study
Published in BJS open (05-05-2023)“…Abstract Background Colorectal cancer causes the majority of large bowel obstructions and surgical resection remains the gold standard for curative treatment…”
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A painful right knee after a motorcycle accident
Published in Nederlands tijdschrift voor geneeskunde (2016)“…A 48-year-old male presented with a painful right knee after a motorcycle accident. Peripheral pulsations in the lower right leg were absent. X-ray indicated a…”
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Mesenteric venous thrombosis during pregnancy; a rare cause of acute ischaemia of the small intestine
Published in Nederlands tijdschrift voor geneeskunde (2016)“…Acute ischaemia of the small intestine is caused by mesenteric venous thrombosis in 5-15% of patients. The non-specific symptoms frequently lead to a…”
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A scoring system to predict the severity of appendicitis in children
Published in The Journal of surgical research (01-02-2016)“…Abstract Background It appears that two forms of appendicitis exist. Preoperative distinction between the two is essential to optimize treatment outcome. This…”
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Isolation and growth of yeasts in the presence of aureomycin
Published in Journal of bacteriology (01-07-1952)Get full text
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The stable bacteriocin release protein signal peptide, expressed as a separate entity, functions in the release of cloacin DF13
Published in FEMS microbiology letters (01-09-1995)“…The pCloDF13 encoded bacteriocin release protein (BRP) plays a role in the release of the bacteriocin cloacin DF13. The BRP signal peptide is stable after…”
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Application of the PCLODF13 bacteriocin release protein in the release of heterologous proteins by Escherichia coli : production of plant α-galactosidase
Published in Biotechnology letters (01-08-1995)“…The bacteriocin release protein (BRP) mediated release of several eukaryotic proteins was studied in Escherichia coli. The genes for the plant proteins alpha…”
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