Clinical and pathological study of chordoma in the skull base
To study the clinical and pathological characteristics of chordoma in the skull base. The clinical manifestation, radiological finding and pathological characteristics in 20 patients with skull base chordoma were reviewed. Among them, 7 were immunohistochemical stained for keratin, epithelial membra...
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| Published in: | Zhonghua er bi yan hou ke za zhi Vol. 37; no. 2; p. 99 |
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| Main Authors: | , , , , , , |
| Format: | Journal Article |
| Language: | Chinese |
| Published: |
China
01-04-2002
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| Subjects: | |
| Online Access: | Get more information |
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| Summary: | To study the clinical and pathological characteristics of chordoma in the skull base.
The clinical manifestation, radiological finding and pathological characteristics in 20 patients with skull base chordoma were reviewed. Among them, 7 were immunohistochemical stained for keratin, epithelial membrane antigen, vimentin, glial fibrillary acidic protein and desmen, 2 were studied by electron microscope. 19 patients received surgical resection(5 cases were assisted by nasal endoscope). Eleven patients received radiation therapy. All 19 patients were followed-up for 3-5 years after treatment.
(1) Clinical type were divided into four types in this group according to symptoms, sign, imaging features, operation finding, the original places and the expansive direction of the tumor. Seller type 5 cases, clival type 9 cases, occipito-temproral type 2 cases and extent type 4 cases. One case with multiple cranial never palsies died due to the pressure on brain stem by the neoplasm, was autopsied prove lungs metastasis. 5 |
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| ISSN: | 0412-3948 |