Search Results - "Tenembaum, Sílvia"
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International Pediatric Multiple Sclerosis Study Group criteria for pediatric multiple sclerosis and immune-mediated central nervous system demyelinating disorders: revisions to the 2007 definitions
Published in Multiple sclerosis (01-09-2013)“…Background: There has been tremendous growth in research in pediatric multiple sclerosis (MS) and immune mediated central nervous system demyelinating…”
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Pediatric demyelinating disease and anti‐MOG antibody
Published in Clinical & experimental neuroimmunology (01-02-2021)“…Significant progress has been made in the field of pediatric neuroimmunology over the past few years. With the detection of conformationally correct myelin…”
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Acute disseminated encephalomyelitis
Published in Handbook of clinical neurology (2013)“…The advent of magnetic resonance imaging (MRI) has contributed to increase the interest and awareness in childhood white matter disorders. Pediatric…”
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Pediatric Multiple Sclerosis: Distinguishing Clinical and MR Imaging Features
Published in Neuroimaging clinics of North America (01-05-2017)“…This article presents an overview of evolving diagnostic criteria of pediatric multiple sclerosis and related disorders, emphasizing distinguishing clinical…”
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Treatment of Acute Disseminated Encephalomyelitis
Published in Current treatment options in neurology (01-06-2012)“…Opinion statement Acute disseminated encephalomyelitis (ADEM) is an inflammatory demyelinating disease, characterized by an acute onset of polyfocal central…”
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Rituximab in patients with pediatric multiple sclerosis and other demyelinating disorders of the CNS: Practical considerations
Published in Multiple Sclerosis Journal (01-10-2021)“…Anti-CD20 therapies have established efficacy in the treatment of immune-mediated neurological and non-neurological diseases. Rituximab, one of the first…”
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Book Review Journal Article -
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Treatment of neuromyelitis optica: Review and recommendations
Published in Multiple sclerosis and related disorders (01-10-2012)“…Abstract Neuromyelitis optica (NMO) is an autoimmune demyelinating disease preferentially targeting the optic nerves and spinal cord. Once regarded as a…”
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Interferon beta-1a treatment in childhood and juvenile-onset multiple sclerosis
Published in Neurology (08-08-2006)“…The authors studied the safety and tolerability of subcutaneous interferon beta-1a at different doses in 24 children with clinically definite multiple…”
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Pediatric Multiple Sclerosis
Published in Neuroimaging clinics of North America (01-05-2017)“…This article presents an overview of evolving diagnostic criteria of pediatric multiple sclerosis and related disorders, emphasizing distinguishing clinical…”
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Subcutaneous Interferon Beta-1a in Pediatric Multiple Sclerosis: A Retrospective Study
Published in Journal of child neurology (01-07-2013)“…To expand current knowledge, we examined the safety and tolerability of subcutaneous interferon β-1a in patients with pediatric-onset multiple sclerosis…”
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Disseminated encephalomyelitis in children
Published in Clinical neurology and neurosurgery (01-11-2008)“…Abstract The advent of MRI has contributed to increase the interest and awareness in childhood white matter disorders. A major priority is to distinguish…”
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Journal Article Conference Proceeding -
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Age-Dependent B Cell Autoimmunity to a Myelin Surface Antigen in Pediatric Multiple Sclerosis
Published in The Journal of immunology (1950) (15-09-2009)“…Multiple sclerosis (MS) typically manifests in early to mid adulthood, but there is increasing recognition of pediatric-onset MS, aided by improvements in…”
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Treatment of multiple sclerosis and neuromyelitis optica in children and adolescents
Published in Clinical neurology and neurosurgery (01-12-2013)“…Abstract Paediatric multiple sclerosis (MS) accounts for up to 5% of all MS cases. No therapies have been formally approved for paediatric patients with MS…”
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Clinical features and viral serologies in children with multiple sclerosis: a multinational observational study
Published in Lancet neurology (01-09-2007)“…Summary Background The full spectrum of clinical manifestations and outcome, and the potential importance of regional or demographic features or viral triggers…”
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Therapy of multiple sclerosis in children and adolescents
Published in Clinical neurology and neurosurgery (01-09-2010)“…Abstract Background Paediatric multiple sclerosis accounts for up to 10% of all MS cases. The initial course of the disease is relapsing-remitting in most…”
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Journal Article Conference Proceeding -
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Population Pharmacodynamic Modelling of the CD19+ Suppression Effects of Rituximab in Paediatric Patients with Neurological and Autoimmune Diseases
Published in Pharmaceutics (01-10-2023)“…Background: Limited pharmacotherapy and the failure of conventional treatments in complex pathologies in children lead to increased off-label use of rituximab…”
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Serum autoantibodies to myelin peptides distinguish acute disseminated encephalomyelitis from relapsing– remitting multiple sclerosis
Published in Multiple sclerosis (01-11-2013)“…Background and objective: Acute disseminated encephalomyelitis (ADEM) and relapsing–remitting multiple sclerosis (RRMS) share overlapping clinical, radiologic…”
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Ethical challenges in paediatric clinical trials in multiple sclerosis
Published in Therapeutic Advances in Neurological Disorders (01-05-2012)“…Children and adolescents with multiple sclerosis (MS) are reported to show high rates of relapse early in the course of the disease as well as cognitive…”
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Book Review Journal Article -
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Update on biomarkers in neuromyelitis optica
Published in Neurology : neuroimmunology & neuroinflammation (01-08-2015)“…Neuromyelitis optica (NMO) (and NMO spectrum disorder) is an autoimmune inflammatory disease of the CNS primarily affecting spinal cord and optic nerves…”
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Emerging concepts in pediatric-onset multiple sclerosis and related disorders
Published in Current opinion in pediatrics (01-12-2010)“…Pediatric-onset multiple sclerosis (MS) is increasingly recognized. Conversely, MS diagnosis in the pediatric population continues to be challenging,…”
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