Search Results - "Tenaglia, Alan N."

Randomized dose-ranging controlled trial of AQ-13, a candidate antimalarial, and chloroquine in healthy volunteers by Mzayek, Fawaz, Deng, Haiyan, Mather, Frances J, Wasilevich, Elizabeth C, Liu, Huayin, Hadi, Christiane M, Chansolme, David H, Murphy, Holly A, Melek, Bekir H, Tenaglia, Alan N, Mushatt, David M, Dreisbach, Albert W, Lertora, Juan J L, Krogstad, Donald J

“…To determine: (1) the pharmacokinetics and safety of an investigational aminoquinoline active against multidrug-resistant malaria parasites (AQ-13), including…”
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Therapeutic angiogenesis with recombinant fibroblast growth factor-2 for intermittent claudication (the TRAFFIC study): a randomised trial by Lederman, Robert J, Mendelsohn, Farrell O, Anderson, R David, Saucedo, Jorge F, Tenaglia, Alan N, Hermiller, James B, Hillegass, William B, Rocha-Singh, Krishna, Moon, Thomas E, Whitehouse, MJ, Annex, Brian H

“…Recombinant fibroblast growth factor-2 (rFGF-2) improves perfusion in models of myocardial and hindlimb ischaemia. We investigated whether one or two doses of…”
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In vivo validation of compensatory enlargement of atherosclerotic coronary arteries by Hermiller, James B., Tenaglia, Alan N., Kisslo, Katherine B., Phillips, Harry R., Bashore, Thomas M., Stack, Richard S., Davidson, Charles J.

“…Necropsy examinations and epicardial ultrasound studies have suggested that atherosclerotic coronary arteries undergo compensatory enlargement. This increase…”
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Levels of Expression of P-Selectin, E-Selectin, and Intercellular Adhesion Molecule-1 in Coronary Atherectomy Specimens from Patients With Stable and Unstable Angina Pectoris by Tenaglia, Alan N, Buda, Andrew J, Wilkins, Robert G, Barron, Michael K, Jeffords, Paul R, Vo, Khoa, Jordan, Maureen O, Kusnick, Barry A, Lefer, David J

“…Unstable angina occurs when atherosclerotic plaque ruptures. Recent evidence suggests a role for inflammation in this process. Leukocyte-endothelial cell…”
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Unrecognized left main coronary artery disease in patients undergoing interventional procedures by Hermiller, James B., Buller, Christopher E., Tenaglia, Alan N., Kisslo, Katherine B., Phillips, Harry R., Bashore, Thomas M., Stack, Richard S., Davidson, Charles J.

“…Selective, coronary arteriographic, catheterbased, intravascular ultrasound images were obtained to determine the presence and extent of angiographically…”
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Intimal hyperplasia after balloon injury is attenuated by blocking selectins by BARRON, M. K, LAKE, R. S, BUDA, A. J, TENAGLIA, A. N

“…Cell adhesion molecules facilitate the adherence of platelets and leukocytes to the vascular endothelium in response to injury. Restenosis after balloon…”
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Design of the therapeutic angiogenesis with recombinant fibroblast growth factor-2 for intermittent claudication (TRAFFIC) trial by Lederman, Robert J., Tenaglia, Alan N., Anderson, R.David, Hermiller, James B., Rocha-Singh, Krishna, Mendelsohn, Farrell O., Hiatt, William R., Moon, Thomas, Whitehouse, M.J., Annex, Brian H.

“…The Therapeutic Angiogenesis With Recombinant Fibroblast Growth Factor-2 for Intermittent Claudication (TRAFFIC) is a large, randomized, placebo-controlled,…”
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Predicting the risk of abrupt vessel closure after angioplasty in an individual patient by Tenaglia, Alan N., Fortin, Donald F., Califf, Robert M., Frid, David J., Nelson, Charlotte L., Gardner, Laura, Miller, Michael, Navetta, Frank I., Smith, Jack E., Tcheng, James E., Stack, Richard S.

“…Objectives. We proposed to examine the relation between angiographic morphologic characteristics and abrupt closure after coronary angioplasty and to develop…”
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Psychosocial status in chronic illness. A comparative analysis of six diagnostic groups by Cassileth, B R, Lusk, E J, Strouse, T B, Miller, D S, Brown, L L, Cross, P A, Tenaglia, A N

“…Assumptions that psychological attributes are specific to particular diagnoses characterize many investigations of chronically ill patients. We studied 758…”
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Long-term outcome following successful reopening of abrupt closure after coronary angioplasty by Tenaglia, Alan N., Fortin, Donald F., Frid, David J., Gardner, Laura H., Nelson, Charlotte L., Tcheng, James E., Stack, Richard S., Califf, Robert M.

“…Abrupt closure after coronary angioplasty is often successfully treated by repeat dilation. Long-term follow-up, including 6-month repeat catheterization and…”
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Effect of short-term treatment with a monoclonal antibody to P-selectin on balloon catheter-induced: intimal hyperplasia, re-endothelialization, and attenuation of endothelial-dependent relaxation by Akers, D L, Lefer, D J, Chen, I L, Wilkens, R G, Rice, J, Aurora, H, Osgood, T A, Bedi, B, Tenaglia, A N, Buda, A J, Kadowitz, P J, McNamara, D B

“…The effects of an anti-P-selectin monoclonal antibody (MAb, PB1.3; Cytel Corporation) on neoendothelialization; neoendothelial function, as evidenced by…”
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Treatment of long coronary artery narrowings with long angioplasty balloon catheters by Tenaglia, Alan N., Zidar, James P., Jackman, John D., Fortin, Donald F., Krucoff, Mitchell W., Tcheng, James E., Phillips, Harry R., Stack, Richard S.

“…Balloon angioplasty of long coronary artery narrowings has been associated with a lower rate of acute success, and a higher rate of acute complications and…”
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Angioplasty for Acute Coronary Syndromes by Tenaglia, Alan N, Stack, Richard S

“…The acute ischemic syndromes (unstable angina and acute myocardial infarction) are often treated with percutaneous transluminal coronary angioplasty…”
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Intracoronary ultrasound: insights into mechanisms and results of coronary interventions by Schreiter, S W, Tenaglia, A N, Buda, A J

“…Intracoronary ultrasound imaging is a modality which allows in vivo cross-sectional visualization of coronary arteries similar to that obtained by pathology…”
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Spontaneous Coronary Artery Spasm Documented in a Young Woman: A Case Report by CAMPEAU, RICHARD J, SPELLMAN, JOHN G, TENAGLIA, ALAN N

“…A 35-year-old woman with coronary risk factors presented with nonexertional atypical burning chest pain of 1 week's duration. A myocardial perfusion study with…”
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Patients' perceptions of the cosmetic impact of melanoma resection by Cassileth, B R, Lusk, E J, Tenaglia, A N

“…This study investigated the relationship between primary versus grafted closure for melanoma and the cosmetic impact on the patient of the resulting scar. A…”
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Neovascularization in atherectomy specimens from patients with unstable angina: Implications for pathogenesis of unstable angina by Tenaglia, Alan N., Peters, Kevin G., Sketch, Jr, Michael H., Annex, Brian H.

“…Although neovascularization has been noted in atherosclerotic plaque, the presence of neovascularization has not been correlated with clinical syndromes. This…”
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Mechanisms of balloon angioplasty and directional coronary atherectomy as assessed by intracoronary ultrasound by Tenaglia, Alan N., Buller, Christopher E., Kisslo, Katherine B., Stack, Richard S., Davidson, Charles J.

“…Objective. This study was designed to use intracoronary ultrasound imaging to elucidate the physical effects of balloon angioplasty and directional coronary…”
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Clinical risks of thrombolytic therapy by Califf, Robert M., Fortin, Donald F., Tenaglia, Alan N., Sane, David C.

“…Understanding the clinical risks of intravenous thrombolytic therapy is critical to appropriate patient selection. The major risks can be classified into 5…”
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Intravascular ultrasound and balloon percutaneous transluminal coronary angioplasty by Tenaglia, A N

“…Intracoronary ultrasound provides unique information during percutaneous transluminal coronary angioplasty (PTCA), including more accurate measurement of…”
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