Search Results - "Ten Haaft, Peter"

Qualitative T-Helper Responses to Multiple Viral Antigens Correlate with Vaccine-Induced Immunity to Simian/Human Immunodeficiency Virus Infection by MOOIJ, Petra, NIEUWENHUIS, Ivonne G, MOREIN, Brør, CAFARO, Aurelio, ENSOLI, Barbara, WAGNER, Ralf, HEENEY, Jonathan L, KNOOP, Christiaan J, DAMS, Robert W, BOGERS, Willy M. J. M, TEN HAAFT, Peter J. F, NIPHUIS, Henk, KOORNSTRA, Wim, BIELER, Kurt, KÖSTLER, Josef

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Peroxicretion: a novel secretion pathway in the eukaryotic cell by Sagt, Cees M J, ten Haaft, Peter J, Minneboo, Ingeborg M, Hartog, Miranda P, Damveld, Robbert A, van der Laan, Jan Metske, Akeroyd, Michiel, Wenzel, Thibaut J, Luesken, Francisca A, Veenhuis, Marten, van der Klei, Ida, de Winde, Johannes H

“…Enzyme production in microbial cells has been limited to secreted enzymes or intracellular enzymes followed by expensive down stream processing. Extracellular…”
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Co-receptor Usage of BOB/GPR15 in Addition to CCR5 Has No Significant Effect on Replication of Simian Immunodeficiency Virus In Vivo by Pöhlmann, Stefan, Stolte, Nicole, Münch, Jan, Ten Haaft, Peter, Heeney, Jonathan L., Stahl-Hennig, Christiane, Kirchhoff, Frank

“…Human immunodeficiency virus type 2 (HIV-2) and the closely related simian immunodeficiency viruses (SIVs) frequently use the orphan receptor BOB/GPR15 in…”
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T-Cell Receptor:CD3 Down-Regulation Is a Selected In Vivo Function of Simian Immunodeficiency Virus Nef but Is Not Sufficient for Effective Viral Replication in Rhesus Macaques by Münch, Jan, Janardhan, Ajit, Stolte, Nicole, Stahl-Hennig, Christiane, ten Haaft, Peter, Heeney, Jonathan L., Swigut, Tomek, Kirchhoff, Frank, Skowronski, Jacek

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MHC Class I Alleles Influence Set-Point Viral Load and Survival Time in Simian Immunodeficiency Virus-Infected Rhesus Monkeys by Muhl, Thorsten, Krawczak, Michael, ten Haaft, Peter, Hunsmann, Gerhard, Sauermann, Ulrike

“…In HIV-infected humans and SIV-infected rhesus macaques, host genes influence viral containment and hence the duration of the disease-free latency period. Our…”
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A Pathogenic Threshold of Virus Load Defined in Simian Immunodeficiency Virus- or Simian-Human Immunodeficiency Virus-Infected Macaques by Ten Haaft, P, Verstrepen, B, Uberla, K, Rosenwirth, B, Heeney, J

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Long-term protection against SHIV89.6P replication in HIV-1 Tat vaccinated cynomolgus monkeys by Maggiorella, Maria Teresa, Baroncelli, Silvia, Michelini, Zuleika, Fanales-Belasio, Emanuele, Moretti, Sonia, Sernicola, Leonardo, Cara, Andrea, Negri, Donatella R.M, Buttò, Stefano, Fiorelli, Valeria, Tripiciano, Antonella, Scoglio, Arianna, Caputo, Antonella, Borsetti, Alessandra, Ridolfi, Barbara, Bona, Roberta, Haaft, Peter ten, Macchia, Iole, Leone, Pasqualina, Pavone-Cossut, Maria Rosaria, Nappi, Filomena, Ciccozzi, Massimo, Heeney, Jonathan, Titti, Fausto, Cafaro, Aurelio, Ensoli, Barbara

“…Vaccination with a biologically active Tat protein or tat DNA contained infection with the highly pathogenic SHIV89.6P virus, preventing CD4 T-cell decline and…”
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Evidence for Viral Virulence as a Predominant Factor Limiting Human Immunodeficiency Virus Vaccine Efficacy by Mooij, P, Bogers, W M, Oostermeijer, H, Koornstra, W, Ten Haaft, P J, Verstrepen, B E, Van Der Auwera, G, Heeney, J L

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Importance of the N-Distal AP-2 Binding Element in Nef for Simian Immunodeficiency Virus Replication and Pathogenicity in Rhesus Macaques by BRENNER, Matthias, MÜNCH, Jan, TEN HAAFT, Peter, SWIGUT, Tomek, HRECKA, Katarzyna, SKOWRONSKI, Jacek, KIRCHHOFF, Frank, SCHINDLER, Michael, WILDUM, Steffen, STOLTE, Nicole, STAHL-HENNIG, Christiane, FUCHS, Dietmar, MÄTZ-RENSING, Kerstin, FRANZ, Monika, HEENEY, Jonathan

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Transmission of Simian Immunodeficiency Virus SIVcpz and the Evolution of Infection in the Presence and Absence of Concurrent Human Immunodeficiency Virus Type 1 Infection in Chimpanzees by HEENEY, Jonathan L, RUTJENS, Erik, COBB, Kathy, KESTENS, Luc, DAVIS, David, VAN DER GROEN, Guido, COURGNAUD, Valerie, PEETERS, Martine, MURTHY, Krishna K, VERSCHOOR, Ernst J, NIPHUIS, Henk, TEN HAAFT, Peter, ROUSE, Scott, MCCLURE, Hazel, BALLA-JHAGJHOORSINGH, Sunita, BOGERS, Willy, SALAS, Mary

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Single-cycle immunodeficiency viruses provide strategies for uncoupling in vivo expression levels from viral replicative capacity and for mimicking live-attenuated SIV vaccines by Kuate, Seraphin, Stahl-Hennig, Christiane, Haaft, Peter ten, Heeney, Jonathan, Überla, Klaus

“…To reduce the risks associated with live-attenuated immunodeficiency virus vaccines, single-cycle immunodeficiency viruses (SCIVs) were developed by primer…”
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Direct Inoculation of Simian Immunodeficiency Virus from Sooty Mangabeys in Black Mangabeys (Lophocebus aterrimus): First Evidence of AIDS in a Heterologous African Species and Different Pathologic Outcomes of Experimental Infection by APETREI, Cristian, GORMUS, Bobby, VEAZEY, Ronald S, LACKNER, Andrew A, BASKIN, Gary, HEENEY, Jonathan, MARX, Preston A, PANDREA, Ivona, METZGER, Michael, TEN HAAFT, Peter, MARTIN, Louis N, BOHM, Rudolf, ALVAREZ, Xavier, KOOPMAN, Gerrit, MURPHEY-CORB, Michael

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Better protective effects in rhesus macaques by combining systemic and mucosal application of a dual component vector vaccine after rectal SHIV89.6P challenge compared to systemic vaccination alone by Stolte-Leeb, Nicole, Bieler, Kurt, Kostler, Josef, Heeney, Jonathan, Haaft, Peter Ten, Suh, You-Suk, Hunsmann, Gerhard, Stahl-Hennig, Christiane, Wagner, Ralf

“…In this study we investigated the efficacy of a multigenic DNA prime/modified vaccinia Ankara (MVA)boost vaccine approach, followed by mucosal challenge with…”
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A simian immunodeficiency virus V3 loop mutant that does not efficiently use CCR5 or common alternative coreceptors is moderately attenuated in vivo by Pöhlmann, Stefan, Münch, Jan, Aziz, Sheriff, Reeves, Jacqueline D, Otto, Claas, Leslie, George J, Hofmann, Heike, Puffer, Bridget A, Baribaud, Frédéric, Marzi, Andrea, Gramberg, Thomas, Chen, Zhiwei, Stolte, Nicole, Haaft, Peter Ten, Heeney, Jonathan L, Stahl-Hennig, Christiane, Mätz-Rensing, Kerstin, Schneider, Thomas, Doms, Robert W, Kirchhoff, Frank

“…Abstract Sexually transmitted HIV-1 strains utilize the chemokine receptor CCR5 for viral entry and inhibitors targeting this coreceptor offer great promise…”
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Comparison of Immunity Generated by Nucleic Acid-, MF59-, and ISCOM-Formulated Human Immunodeficiency Virus Type 1 Vaccines in Rhesus Macaques: Evidence for Viral Clearance by Verschoor, E J, Mooij, P, Oostermeijer, H, van der Kolk, M, ten Haaft, P, Verstrepen, B, Sun, Y, Morein, B, Akerblom, L, Fuller, D H, Barnett, S W, Heeney, J L

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The Simian Immunodeficiency Virus Δnef Vaccine, after Application to the Tonsils of Rhesus Macaques, Replicates Primarily within CD4+ T Cells and Elicits a Local Perforin-Positive CD8+ T-Cell Response by Stahl-Hennig, Christiane, Steinman, Ralph M., Ten Haaft, Peter, Überla, Klaus, Stolte, Nicole, Saeland, Sem, Tenner-Racz, Klara, Racz, Paul

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Readily acquired secondary infections of human and simian immunodeficiency viruses following single intravenous exposure in non-human primates by Haaft, Peter ten, Verschoor, Ernst J, Verstrepen, Babs, Niphuis, Henk, Dubbes, Rob, Koornstra, Wim, Bogers, Willy, Rosenwirth, Brigitte, Heeney, Jonathan L

“…Department of Virology, Biomedical Primate Research Centre, PO Box 3306, 2280 GH Rijswijk, The Netherlands Correspondence Jonathan L. Heeney heeney{at}bprc.nl…”
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Antiretroviral Therapy during Primary Immunodeficiency Virus Infection Can Induce Persistent Suppression of Virus Load and Protection from Heterologous Challenge in Rhesus Macaques by Rosenwirth, B, ten Haaft, P, Bogers, W M, Nieuwenhuis, I G, Niphuis, H, Kuhn, E M, Bischofberger, N, Heeney, J L, Uberla, K

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Specific passage of simian immunodeficiency virus from end-stage disease results in accelerated progression to AIDS in rhesus macaques by Holterman, Lennart, Niphuis, Henk, Ten Haaft, Peter J F, Goudsmit, Jaap, Baskin, Gary, Heeney, Jonathan L

“…To determine whether passage of late-stage variants of simian immunodeficiency virus (SIV) would lead to a more virulent infection and rapid disease…”
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Relationship between viral load in blood, cerebrospinal fluid, brain tissue and isolated microglia with neurological disease in macaques infected with different strains of SIV by Demuth, M, Czub, S, Sauer, U, Koutsilieri, E, Haaft, P, Heeney, J, Stahl-Hennig, C, ter Meulen, V, Sopper, S

“…The role of the viral burden in the brain for the pathogenesis of human immunodeficiency virus-associated neurological disorders is still unclear. To address…”
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