Phenotypic and genotypic characterization of Aspergillus lentulus and Aspergillus fumigatus isolates in a patient with probable invasive aspergillosis

1 Departamento de Microbiología, Parasitología e Inmunología, Facultad de Medicina, Universidad de Buenos Aires, Paraguay 2150, Piso 11 (1121), Buenos Aires, Argentina 2 Centro de Educación Médica e Investigaciones Clínicas Dr. Norberto Quirno (CEMIC), Buenos Aires, Argentina Correspondence Maria...

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Published in:	Journal of medical microbiology Vol. 58; no. 3; pp. 391 - 395
Main Authors:	Montenegro, Graciela, Sanchez Puch, Silvia, Jewtuchowicz, Virginia M, Pinoni, Maria V, Relloso, Silvia, Temporitti, Elena, Iovannitti, Cristina A, Mujica, Maria T
Format:	Journal Article
Language:	English
Published:	Reading Soc General Microbiol 01-03-2009 Society for General Microbiology
Subjects:	Adult Argentina Aspergillosis - microbiology Aspergillus - classification Aspergillus - genetics Aspergillus - growth & development Aspergillus - isolation & purification Aspergillus fumigatus Aspergillus fumigatus - classification Aspergillus fumigatus - genetics Aspergillus fumigatus - growth & development Aspergillus fumigatus - isolation & purification Base Sequence Biological and medical sciences Bronchoalveolar Lavage Fluid - microbiology DNA, Fungal - chemistry Fatal Outcome Female Fundamental and applied biological sciences. Psychology Genotype Humans Immunocompromised Host Infectious diseases Medical sciences Microbiology Miscellaneous Molecular Sequence Data Mycology Phenotype Phylogeny Sequence Alignment Argentina Fungi Infection Human Mycosis Microbiology Aspergillosis Isolate Fungi Imperfecti Aspergillus fumigatus
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Summary:	1 Departamento de Microbiología, Parasitología e Inmunología, Facultad de Medicina, Universidad de Buenos Aires, Paraguay 2150, Piso 11 (1121), Buenos Aires, Argentina 2 Centro de Educación Médica e Investigaciones Clínicas Dr. Norberto Quirno (CEMIC), Buenos Aires, Argentina Correspondence Maria T. Mujica mtmujica{at}gmail.com Received August 16, 2008 Accepted November 21, 2008 Characteristic morphological and phylogenetic analyses demonstrated the presence of Aspergillus fumigatus and Aspergillus lentulus as the aetiological agents in a case of probable invasive aspergillosis (IA). This is believed to be the first report of an A. lentulus strain isolated from a patient with probable IA in Argentina. Abbreviations: AMB, amphotericin B; BAL, bronchoalveolar lavage; CAS, caspofungin; IA, invasive aspergillosis; ITS, internal transcribed spacer; VRZ, voriconazole. The GenBank/EMBL/DDBJ accession numbers for the benA, rodA , mtcytb and ITS sequences of Aspergillus reported in this study are EU254411, EU254412, EU254414 and EU254413 for RS : B2007AR, and EU254415, EU254416, EU254418 and EU254417 for RS : V2007AR.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 ObjectType-Case Study-2 ObjectType-Feature-4 ObjectType-Report-1 ObjectType-Article-3
ISSN:	0022-2615 1473-5644
DOI:	10.1099/jmm.0.005942-0