Search Results - "Temple, Mark"

Real-time audio and visual display of the Coronavirus genome by Temple, Mark D

“…This paper describes a web based tool that uses a combination of sonification and an animated display to inquire into the SARS-CoV-2 genome. The audio data is…”
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An auditory display tool for DNA sequence analysis by Temple, Mark D

“…DNA Sonification refers to the use of an auditory display to convey the information content of DNA sequence data. Six sonification algorithms are presented…”
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A website to identify shared genes in Saccharomyces cerevisiae homozygous deletion library screens by Temple, Mark D

“…The homozygous yeast deletion library includes approximately 4800 diploid strains each containing one deleted non-essential gene. Hundreds of publications have…”
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Weekend specialist intensity and admission mortality in acute hospital trusts in England: a cross-sectional study by Aldridge, Cassie, PhD, Bion, Julian, Prof, Boyal, Amunpreet, MSc, Chen, Yen-Fu, PhD, Clancy, Mike, MSc, Evans, Tim, Prof, Girling, Alan, MA, Lord, Joanne, PhD, Mannion, Russell, Prof, Rees, Peter, MA, Roseveare, Chris, BM, Rudge, Gavin, MSc, Sun, Jianxia, MSc, Tarrant, Carolyn, PhD, Temple, Mark, MD, Watson, Sam, PhD, Lilford, Richard, Prof

“…Summary Background Increased mortality rates associated with weekend hospital admission (the so-called weekend effect) have been attributed to suboptimum…”
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Twenty years later, the evolution of origami DNA by Temple, Mark D.

“…Twenty years ago Trends in Biochemical Sciences published an innovative origami template for modeling the DNA double helix. Presented here are adaptations of…”
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Risk factors for postoperative hemorrhage following tonsillectomy by Tomkinson, Alun, Harrison, Wendy, Owens, David, Harris, Susan, McClure, Victoria, Temple, Mark

“…Objectives/Hypothesis: To identify the main risk factors associated with postoperative hemorrhage following tonsillectomy. Study Design: Prospective…”
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The interactions of novel mononuclear platinum-based complexes with DNA by Johnson, Ben W, Burgess, Mark W, Murray, Vincent, Aldrich-Wright, Janice R, Temple, Mark D

“…Cisplatin has been widely used for the treatment of cancer and its antitumour activity is attributed to its capacity to form DNA adducts, predominantly at…”
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Complex cellular responses to reactive oxygen species by Temple, Mark D., Perrone, Gabriel G., Dawes, Ian W.

“…Genome-wide analyses of yeast provide insight into cellular responses to reactive oxygen species (ROS). Many deletion mutants are sensitive to at least one…”
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Characterisation of the DNA sequence specificity, cellular toxicity and cross-linking properties of novel bispyridine-based dinuclear platinum complexes by Johnson, Ben W, Murray, Vincent, Temple, Mark D

“…The anti-tumour activity of cisplatin is thought to be a result of its capacity to form DNA adducts which prevent cellular processes such as DNA replication…”
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Evidence of Person-to-Person Transmission of Oseltamivir-Resistant Pandemic Influenza A(H1N1) 2009 Virus in a Hematology Unit by Moore, Catherine, Galiano, Monica, Lackenby, Angie, Abdelrahman, Tamer, Barnes, Rosemary, Evans, Meirion R., Fegan, Christopher, Froude, Susannah, Hastings, Mark, Knapper, Steven, Litt, Emma, Price, Nicola, Salmon, Roland, Temple, Mark, Davies, Eleri

“…We describe the first confirmed person-to-person transmission of oseltamivir-resistant pandemic influenza A(H1N1) 2009 virus that occurred in a hematology unit…”
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Involvement of oxidative stress response genes in redox homeostasis, the level of reactive oxygen species, and ageing in Saccharomyces cerevisiae by Drakulic, Tamara, Temple, Mark D., Guido, Ron, Jarolim, Stefanie, Breitenbach, Michael, Attfield, Paul V., Dawes, Ian W.

“…Saccharomyces cerevisiae mutants lacking oxidative stress response genes were used to investigate which genes are required under normal aerobic conditions to…”
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Assessing the role of contact tracing in a suspected H7N2 influenza A outbreak in humans in Wales by Eames, Ken T D, Webb, Cerian, Thomas, Kathrin, Smith, Josie, Salmon, Roland, Temple, J Mark F

“…The detailed analysis of an outbreak database has been undertaken to examine the role of contact tracing in controlling an outbreak of possible avian influenza…”
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Compulsory vaccination: case isolation is likely to be more effective

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Compulsory vaccination: case isolation is likely to be more effective by Temple, Mark

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Inpatient care: should the general physician now take charge? by Kirthi, Varo, Temple, R Mark, Patterson, Linda J

“…In an ageing population, patients are living longer with one or more chronic disease, and with acute illnesses increasingly extending outside the boundaries of…”
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Deviation from national guidance can have better results by Temple, Mark

“…Following guidance based on evidence from randomised controlled trials is recognised to result in suboptimal treatment and recovery in almost all patients. 2…”
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Modelling of the public health effects of smoking in pregnancy in Wales by de Souza, Sikha, Dr, Temple, Mark, MA, Charles, Joanna, PhD, Jones, Siobhan, MPH, Paranjothy, Shantini, PhD, Edwards, Rhiannon Tudor, Prof

“…Abstract Background Wales has higher rates of smoking in pregnancy than does any other UK country. 33% of women in Wales smoked before or during their…”
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Early and Late Presentations of Ethylene Glycol Poisoning by Ting, Stephen M.S., MRCP, Ching, Irene, MRCP, Nair, Harikrishnan, MRCP, Langman, Gerald, FRCPath, Suresh, Vijayan, MRCP, Temple, R. Mark, MD, FRCP

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Footprinting the ‘essential regulatory region’ of the retinoblastoma gene promoter in intact human cells by Temple, Mark D., Murray, Vincent

“…The retinoblastoma tumour suppressor protein is a key cell cycle regulator. Protein–DNA interactions at the retinoblastoma (RB1) promoter, including the…”
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Genome-wide transcriptional responses to a lipid hydroperoxide: adaptation occurs without induction of oxidant defenses by Alic, Nazif, Felder, Thomas, Temple, Mark D, Gloeckner, Christian, Higgins, Vincent J, Briza, Peter, Dawes, Ian W

“…Free radicals can initiate the oxidation of polyunsaturated fatty acids in cells through the process of lipid peroxidation. The genome-wide transcriptional…”
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