Search Results - "Temple, Jillian"

Driver mutations in TP53 are ubiquitous in high grade serous carcinoma of the ovary by Ahmed, Ahmed Ashour, Etemadmoghadam, Dariush, Temple, Jillian, Lynch, Andy G, Riad, Mohamed, Sharma, Raghwa, Stewart, Colin, Fereday, Sian, Caldas, Carlos, deFazio, Anna, Bowtell, David, Brenton, James D

“…Numerous studies have tested the association between TP53 mutations in ovarian cancer and prognosis but these have been consistently confounded by limitations…”
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Spatial and temporal heterogeneity in high-grade serous ovarian cancer: a phylogenetic analysis by Schwarz, Roland F, Ng, Charlotte K Y, Cooke, Susanna L, Newman, Scott, Temple, Jillian, Piskorz, Anna M, Gale, Davina, Sayal, Karen, Murtaza, Muhammed, Baldwin, Peter J, Rosenfeld, Nitzan, Earl, Helena M, Sala, Evis, Jimenez-Linan, Mercedes, Parkinson, Christine A, Markowetz, Florian, Brenton, James D

“…The major clinical challenge in the treatment of high-grade serous ovarian cancer (HGSOC) is the development of progressive resistance to platinum-based…”
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Regulators of Mitotic Arrest and Ceramide Metabolism Are Determinants of Sensitivity to Paclitaxel and Other Chemotherapeutic Drugs by Swanton, Charles, Marani, Michela, Pardo, Olivier, Warne, Patricia H., Kelly, Gavin, Sahai, Erik, Elustondo, Frédéric, Chang, Jenny, Temple, Jillian, Ahmed, Ahmed A., Brenton, James D., Downward, Julian, Nicke, Barbara

“…Cytotoxic drug resistance is a major cause of cancer treatment failure. We report an RNA interference screen to identify genes influencing sensitivity of…”
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ß3 integrin modulates transforming growth factor beta induced (TGFBI) function and paclitaxel response in ovarian cancer cells by Tumbarello, David A, Temple, Jillian, Brenton, James D

“…The extracellular matrix (ECM) has a key role in facilitating the progression of ovarian cancer and we have shown recently that the secreted ECM protein TGFBI…”
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The Extracellular Matrix Protein TGFBI Induces Microtubule Stabilization and Sensitizes Ovarian Cancers to Paclitaxel by Ahmed, Ahmed Ashour, Mills, Anthony D., Ibrahim, Ashraf E.K., Temple, Jillian, Blenkiron, Cherie, Vias, Maria, Massie, Charlie E., Iyer, N. Gopalakrishna, McGeoch, Adam, Crawford, Robin, Nicke, Barbara, Downward, Julian, Swanton, Charles, Bell, Stephen D., Earl, Helena M., Laskey, Ronald A., Caldas, Carlos, Brenton, James D.

“…The extracellular matrix (ECM) can induce chemotherapy resistance via AKT-mediated inhibition of apoptosis. Here, we show that loss of the ECM protein TGFBI…”
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Frequent Recovery and Broad Genotype 2 Diversity Characterize Hepatitis C Virus Infection in Ghana, West Africa by Candotti, Daniel, Temple, Jillian, Sarkodie, Francis, Allain, Jean-Pierre

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Multiplex real-time quantitative RT-PCR assay for hepatitis B virus, hepatitis C virus, and human immunodeficiency virus type 1 by Candotti, Daniel, Temple, Jillian, Owusu-Ofori, Shirley, Allain, Jean-Pierre

“…A multiplex real-time quantitative reverse transcription (RT)-PCR assay was developed for simultaneous detection, identification and quantification of…”
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Identification of a novel GR-ARID1a-P53BP1 protein complex involved in DNA damage repair and cell cycle regulation by Stubbs, Felicity E., Flynn, Benjamin P., Rivers, Caroline A., Birnie, Matthew T., Herman, Andrew, Swinstead, Erin E., Baek, Songjoon, Fang, Hai, Temple, Jillian, Carroll, Jason S., Hager, Gordon L., Lightman, Stafford L., Conway-Campbell, Becky L.

“…ARID1a (BAF250), a component of human SWI/SNF chromatin remodeling complexes, is frequently mutated across numerous cancers, and its loss of function has been…”
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Genomic analysis of genetic heterogeneity and evolution in high-grade serous ovarian carcinoma by Cooke, S L, Ng, C K Y, Melnyk, N, Garcia, M J, Hardcastle, T, Temple, J, Langdon, S, Huntsman, D, Brenton, J D

“…Resistance to chemotherapy in ovarian cancer is poorly understood. Evolutionary models of cancer predict that, following treatment, resistance emerges either…”
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Molecular characterization of occult hepatitis B virus in genotype E-infected subjects by Zahn, Astrid, Li, Chengyao, Danso, Kwabena, Candotti, Daniel, Owusu-Ofori, Shirley, Temple, Jillian, Allain, Jean-Pierre

“…1 Division of Transfusion Medicine, Department of Haematology, University of Cambridge, Cambridge, UK 2 National Health Service Blood and Transplant, Cambridge…”
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The role of tandem duplicator phenotype in tumour evolution in high-grade serous ovarian cancer by Ng, Charlotte KY, Cooke, Susanna L, Howe, Kevin, Newman, Scott, Xian, Jian, Temple, Jillian, Batty, Elizabeth M, Pole, Jessica CM, Langdon, Simon P, Edwards, Paul AW, Brenton, James D

“…High‐grade serous ovarian carcinoma (HGSOC) is characterized by genomic instability, ubiquitous TP53 loss, and frequent development of platinum resistance…”
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β3 integrin modulates transforming growth factor beta induced (TGFBI) function and paclitaxel response in ovarian cancer cells by Tumbarello, David A, Temple, Jillian, Brenton, James D

“…Abstract Background The extracellular matrix (ECM) has a key role in facilitating the progression of ovarian cancer and we have shown recently that the…”
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3 integrin modulates transforming growth factor beta induced function and paclitaxel response in ovarian cancer cells by Tumbarello, David A, Temple, Jillian, Brenton, James D

“…Background The extracellular matrix (ECM) has a key role in facilitating the progression of ovarian cancer and we have shown recently that the secreted ECM…”
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Predonation screening of blood donors with rapid tests: implementation and efficacy of a novel approach to blood safety in resource-poor settings by Owusu-Ofori, Shirley, Temple, Jillian, Sarkodie, Francis, Anokwa, Margaret, Candotti, Daniel, Allain, Jean-Pierre

“…BACKGROUND:  In sub‐Saharan Africa, the percentage of screened blood is limited to approximately 75 percent for human immunodeficiency virus antibodies…”
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Spatial and Temporal Heterogeneity in High-Grade Serous Ovarian Cancer: A Phylogenetic Analysis: e1001789 by Schwarz, Roland F, Ng, Charlotte KY, Cooke, Susanna L, Newman, Scott, Temple, Jillian, Piskorz, Anna M, Gale, Davina, Sayal, Karen, Murtaza, Muhammed, Baldwin, Peter J, Rosenfeld, Nitzan, Earl, Helena M, Sala, Evis, Jimenez-Linan, Mercedes, Parkinson, Christine A, Markowetz, Florian, Brenton, James D

“…Background The major clinical challenge in the treatment of high-grade serous ovarian cancer (HGSOC) is the development of progressive resistance to…”
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Evaluation of a transcription-mediated amplification-based HCV and HIV-1 RNA duplex assay for screening individual blood donations: a comparison with a minipool testing system by Candotti, Daniel, Richetin, Aline, Cant, Barbara, Temple, Jillian, Sims, Cate, Reeves, Ian, Barbara, John A.J., Allain, Jean-Pierre

“…BACKGROUND : NAT was introduced for HCV RNA in 1999 to screen blood donations and improve the safety of the blood supply. STUDY DESIGN AND METHODS : The…”
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BLOOD DONORS AND BLOOD COLLECTION: Predonation screening of blood donors with rapid tests: implementation and efficacy of a novel approach to blood safety in resource-poor settings by Owusu-Ofori, Shirley, Temple, Jillian, Sarkodie, Francis, Anokwa, Margaret, Candotti, Daniel, Allain, Jean-Pierre

“…BACKGROUND:In sub-Saharan Africa, the percentage of screened blood is limited to approximately 75 percent for human immunodeficiency virus antibodies…”
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