Search Results - "Temple, C S"

4-Aminomethylbenzoic acid is a non-translocated competitive inhibitor of the epithelial peptide transporter PepT1 by Meredith, D., Boyd, C. A. R., Bronk, J. R., Bailey, P. D., Morgan, K. M., Collier, I. D., Temple, C. S.

“…4-Aminomethylbenzoic acid, a molecule which mimics the spatial configuration of a dipeptide, competitively inhibits peptide influx in both Xenopus laevis…”
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Proton-coupled oligopeptide transport by rat renal cortical brush border membrane vesicles: a functional analysis using ACE inhibitors to determine the isoform of the transporter by Temple, C.S., Boyd, C.A.R.

“…We demonstrate that the angiotensin-converting enzyme inhibitors enalapril and captopril inhibit the transport of D-Phe-L-Gln into PepT1-expressing Xenopus…”
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A model for the kinetics of neutral and anionic dipeptide-proton cotransport by the apical membrane of rat kidney cortex by Temple, C S, Bailey, P D, Bronk, J R, Boyd, C A

“…1. Kinetics of influx (mediated through peptide-proton cotransport) of two labelled dipeptides has been studied in apical membrane vesicles isolated from rat…”
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Substrate-charge dependence of stoichiometry shows membrane potential is the driving force for proton-peptide cotransport in rat renal cortex by Temple, C S, Bronk, J R, Bailey, P D, Boyd, C A

“…The proton dependence of the transport of three labelled, hydrolysis-resistant synthetic dipeptides carrying a net charge of -1, 0 or +1 has been investigated…”
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Calcitonin and insulin in isobutylcyanoacrylate nanocapsules: protection against proteases and effect on intestinal absorption in rats by Lowe, P J, Temple, C S

“…One of the major limiting steps for the absorption of peptide drugs from the intestine is proteolytic degradation. To slow this degradation, human calcitonin…”
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Peptide Mimics as Substrates for the Intestinal Peptide Transporter by Temple, Catherine S., Stewart, Andrew K., Meredith, David, Lister, Norma A., Morgan, Keith M., Collier, Ian D., Vaughan-Jones, Richard D., Boyd, C. A.R., Bailey, Patrick D., Bronk, J. Ramsey

“…4-Aminophenylacetic acid (4-APAA), a peptide mimic lacking a peptide bond, has been shown to interact with a proton-coupled oligopeptide transporter using a…”
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Modified amino acids and peptides as substrates for the intestinal peptide transporter PepT1 by Meredith, David, Temple, Catherine S., Guha, Nishan, Sword, Corinna J., Boyd, C. A. Richard, Collier, Ian D., Morgan, Keith M., Bailey, Patrick D.

“…The binding affinities of a number of amino‐acid and peptide derivatives by the mammalian intestinal peptide transporter PepT1 were investigated, using the…”
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How to Make Drugs Orally Active: A Substrate Template for Peptide Transporter PepT1 by Bailey, Patrick D., Boyd, C. A. Richard, Bronk, J. Ramsey, Collier, Ian D., Meredith, David, Morgan, Keith M., Temple, Catherine S.

“…By building key structural features into hydrophilic drugs, they can be recognized by the PepT1 transporter system of the small intestine and rendered orally…”
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Recoveries of Banded Ospreys in the West Indies (Recuperación en las Antillas de especímenes anillados de Pandion haliaetus) by Eduardo Santana C., Temple, Stanley A.

“…Of 109 banded Ospreys recovered in the West Indies, 106 (97%) were from eastern continental North America and 74 (68%) were captured between September and…”
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