Search Results - "Tempestilli, Massimo"

Early expansion of myeloid-derived suppressor cells inhibits SARS-CoV-2 specific T-cell response and may predict fatal COVID-19 outcome by Sacchi, Alessandra, Grassi, Germana, Bordoni, Veronica, Lorenzini, Patrizia, Cimini, Eleonora, Casetti, Rita, Tartaglia, Eleonora, Marchioni, Luisa, Petrosillo, Nicola, Palmieri, Fabrizio, D’Offizi, Gianpiero, Notari, Stefania, Tempestilli, Massimo, Capobianchi, Maria Rosaria, Nicastri, Emanuele, Maeurer, Markus, Zumla, Alimuddin, Locatelli, Franco, Antinori, Andrea, Ippolito, Giuseppe, Agrati, Chiara

“…The immunological mechanisms underlying the clinical presentation of SARS-CoV-2 infection and those influencing the disease outcome remain to be defined…”
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Pharmacokinetics of remdesivir and GS-441524 in two critically ill patients who recovered from COVID-19 by Tempestilli, Massimo, Caputi, Priscilla, Avataneo, Valeria, Notari, Stefania, Forini, Olindo, Scorzolini, Laura, Marchioni, Luisa, Ascoli Bartoli, Tommaso, Castilletti, Concetta, Lalle, Eleonora, Capobianchi, Maria R, Nicastri, Emanuele, D’Avolio, Antonio, Ippolito, Giuseppe, Agrati, Chiara

“…Abstract Background Remdesivir is a prodrug of the nucleoside analogue GS-441524 and is under evaluation for treatment of SARS-CoV-2-infected patients…”
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Granulocytic myeloid derived suppressor cells expansion during active pulmonary tuberculosis is associated with high nitric oxide plasma level by El Daker, Sary, Sacchi, Alessandra, Tempestilli, Massimo, Carducci, Claudia, Goletti, Delia, Vanini, Valentina, Colizzi, Vittorio, Lauria, Francesco Nicola, Martini, Federico, Martino, Angelo

“…Tuberculosis (TB) is still the principal cause of death caused by a single infectious agent, and the balance between the bacillus and host defense mechanisms…”
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Plasma concentrations of remdesivir metabolite in a critical COVID-19 patient needing continuous venovenous haemodialysis by Tempestilli, Massimo, Stazi, Giulia Valeria, Maffongelli, Gaetano, Marini, Maria Cristina, Ascoli Bartoli, Tommaso, Ippolito, Giuseppe, Nicastri, Emanuele, Marchioni, Luisa, Agrati, Chiara

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Correction to: Plasma concentrations of remdesivir metabolite in a critical COVID-19 patient needing continuous venovenous haemodialysis by Tempestilli, Massimo, Stazi, Giulia Valeria, Maffongelli, Gaetano, Marini, Maria Cristina, Bartoli, Tommaso Ascoli, Ippolito, Giuseppe, Nicastri, Emanuele, Marchioni, Luisa, Agrati, Chiara

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Vitamin D as Modulator of Drug Concentrations: A Study on Two Italian Cohorts of People Living with HIV Administered with Efavirenz by Cusato, Jessica, Tempestilli, Massimo, Calcagno, Andrea, Vergori, Alessandra, Piselli, Pierluca, Antonucci, Miriam, Avataneo, Valeria, Palermiti, Alice, Notari, Stefania, Antinori, Andrea, Di Perri, Giovanni, Agrati, Chiara, D’Avolio, Antonio

“…To date, vitamin D seems to have a significant role in affecting the prevention and immunomodulation in COVID-19 disease. Nevertheless, it is important to…”
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Cross-subtype immunity against avian influenza in persons recently vaccinated for influenza by Gioia, Cristiana, Castilletti, Concetta, Tempestilli, Massimo, Piacentini, Paola, Bordi, Licia, Chiappini, Roberta, Agrati, Chiara, Squarcione, Salvatore, Ippolito, Giuseppe, Puro, Vincenzo, Capobianchi, Maria R, Poccia, Fabrizio

“…Avian influenza virus (H5N1) can be transmitted to humans, resulting in a severe or fatal disease. The aim of this study was to evaluate the immune…”
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Multicompartment vectors as novel drug delivery systems: selective activation of Tγδ lymphocytes after zoledronic acid delivery by Agrati, Chiara, PhD, Marianecci, Carlotta, PhD, Sennato, Simona, PhD, Carafa, Maria, PhD, Bordoni, Veronica, MSc, Cimini, Eleonora, MSc, Tempestilli, Massimo, MSc, Pucillo, Leopoldo P., MSc, Turchi, Federica, MSc, Martini, Federico, MSc, Borioni, Giorgio, MSc, Bordi, Federico, MSc

“…Abstract Multicompartment nanoscopic carriers can be easily assembled by inducing the aggregation of anionic “hybrid” niosomes by means of cationic…”
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Low Plasma Concentrations of Albumin Influence the Affinity Column―Mediated Immunoassay Method for the Measurement of Tacrolimus in Blood During the Early Period After Liver Transplantation by TEMPESTILLI, Massimo, DI STASIO, Enrico, ROSARIA BASILE, Maria, ELISEI, Federica, ANTONINI, Mario, ETTORRE, Giuseppe Maria, IAPPELLI, Massimo, PAOLO PUCILLO, Leopoldo

“…Monitoring of tacrolimus (TAC) concentrations in transplanted patients is necessary to ensure effective immunosuppression and to avoid adverse side effects…”
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Sildenafil plasma concentrations in two HIV patients with pulmonary hypertension treated with ritonavir-boosted protease inhibitors by Chinello, Pierangelo, Cicalini, Stefania, Pichini, Simona, Pacifici, Roberta, Tempestilli, Massimo, Petrosillo, Nicola

“…Sildenafil is increasingly used for the therapy of pulmonary arterial hypertension (PAH) in HIV infected patients. However, concerns exist about…”
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Simultaneous determination of maraviroc and raltegravir in human plasma by HPLC‐UV by Notari, Stefania, Tommasi, Chiara, Nicastri, Emanuele, Bellagamba, Rita, Tempestilli, Massimo, Pucillo, Leopoldo Paolo, Narciso, Pasquale, Ascenzi, Paolo

“…Therapeutic drug monitoring is pivotal to improve the management of HIV infection. Here, a new HPLC–UV method to quantify simultaneously maraviroc and…”
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Marked increase in etravirine and saquinavir plasma concentrations during atovaquone/proguanil prophylaxis by Tommasi, Chiara, Bellagamba, Rita, Tempestilli, Massimo, D'Avolio, Antonio, Gallo, Anna L, Ivanovic, Jelena, Nicastri, Emanuele, Pucillo, Leopoldo P, Narciso, Pasquale

“…The case of a 32-year-old Caucasian female with multi-drug resistant HIV-1 subtype B infection treated with a salvage regimen including maraviroc, raltegravir,…”
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Sildenafil and bosentan plasma concentrations in a human immunodeficiency virus-infected patient with pulmonary arterial hypertension treated with ritonavir-boosted protease inhibitor by Chinello, Pierangelo, Cicalini, Stefania, Pichini, Simona, Pacifici, Roberta, Tempestilli, Massimo, Cicini, Maria P., Pucillo, Leopoldo P., Petrosillo, Nicola

“…Sildenafil and bosentan are increasingly used for the treatment of pulmonary arterial hypertension (PAH) in HIV-infected patients. However, concerns exist…”
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Transplacental transfer of antiretroviral drugs and newborn birth weight in HIV-infected pregnant women by Ivanovic, Jelena, Nicastri, Emanuele, Anceschi, Maurizio M, Ascenzi, Paolo, Signore, Fabrizio, Pisani, Giuseppe, Vallone, Cristina, Mattia, Elisabetta, Notari, Stefania, Tempestilli, Massimo, Pucillo, Leopoldo P, Narciso, Pasquale

“…Although it is well known that antiretroviral drugs (ARVs) across the placenta in different extents, few data are available concerning the impact of the…”
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Antiretroviral therapeutic drug monitoring in HIV-infected pregnant women: maternal immunovirological outcome at delivery and during the 18 month follow-up period by Nicastri, Emanuele, Ivanovic, Jelena, Signore, Fabrizio, Tempestilli, Massimo, Bellagamba, Rita, Viscione, Magdalena, Pisani, Giuseppe, Vallone, Cristina, Tommasi, Chiara, Gallo, Anna L, De Nardo, Pasquale, Pucillo, Paolo L, Narciso, Pasquale

“…No data are available on the long-term immunovirological outcome of HIV-positive pregnant women experiencing sub-therapeutic antiretroviral drug (ARV)…”
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Interpatient variability in the pharmacokinetics of remdesivir and its main metabolite GS-441524 in treated COVID-19 subjects by Tempestilli, Massimo, Ascoli Bartoli, Tommaso, Benvenuto, Domenico, Stazi, Giulia Valeria, Marchioni, Luisa, Nicastri, Emanuele, Agrati, Chiara

“…Abstract Background Remdesivir is the first antiviral drug against SARS-CoV-2 approved for use in COVID-19 patients. Objectives To study the pharmacokinetic…”
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UPLC–MS/MS method for the simultaneous quantification of sofosbuvir, sofosbuvir metabolite (GS-331007) and daclatasvir in plasma of HIV/HCV co-infected patients by Notari, Stefania, Tempestilli, Massimo, Fabbri, Gabriele, Libertone, Raffaella, Antinori, Andrea, Ammassari, Adriana, Agrati, Chiara

“…•UPLC–MS/MS method for the quantification of SOF, GS-331007 and DCV in a small plasma samples.•Assay validation following FDA guidelines.•The method is…”
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Altered Brain Cholesterol/Isoprenoid Metabolism in a Rat Model of Autism Spectrum Disorders by Cartocci, Veronica, Catallo, Martina, Tempestilli, Massimo, Segatto, Marco, Pfrieger, Frank W., Bronzuoli, Maria Rosanna, Scuderi, Caterina, Servadio, Michela, Trezza, Viviana, Pallottini, Valentina

“…•Modification of cholesterol/isoprenoid homeostasis in brain regions of rats prenatally exposed to valproic acid.•In valproic acid-exposed rats, HMGCR…”
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Pharmacokinetics of bictegravir, emtricitabine and tenofovir alafenamide in a gastrectomized patient with HIV by Tempestilli, Massimo, D’Avolio, Antonio, De Nicolò, Amedeo, Agrati, Chiara, Antinori, Andrea, Cicalini, Stefania

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Mpox as AIDS-defining event with a severe and protracted course: clinical, immunological, and virological implications by Pinnetti, Carmela, Cimini, Eleonora, Mazzotta, Valentina, Matusali, Giulia, Vergori, Alessandra, Mondi, Annalisa, Rueca, Martina, Batzella, Sandro, Tartaglia, Eleonora, Bettini, Aurora, Notari, Stefania, Rubino, Marika, Tempestilli, Massimo, Pareo, Carlo, Falasca, Laura, Del Nonno, Franca, Scarabello, Alessandra, Camici, Marta, Gagliardini, Roberta, Girardi, Enrico, Vaia, Francesco, Maggi, Fabrizio, Agrati, Chiara, Antinori, Andrea

“…A 59-year-old treatment-naive patient with advanced HIV infection presented with a severe and protracted course of mpox (formerly known as monkeypox) that did…”
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