Search Results - "Temesvari, A."

Joining forces: Leveraging novel combination therapies to combat infections with eukaryotic pathogens by Ham, Rachel E, Temesvari, Lesly A

“…Table 1 summarizes the combinations discussed and includes information about whether the combinations were found to be additive (+) or synergistic (*) and…”
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Global estimated Disability-Adjusted Life-Years (DALYs) of diarrheal diseases: A systematic analysis of data from 28 years of the global burden of disease study by Karambizi, Natacha U, McMahan, Christopher S, Blue, Carl N, Temesvari, Lesly A

“…Diarrheal disease (DD)-associated mortality has declined since 1990; however, the incidence of DD has experienced a less-pronounced decrease. Thus, it is…”
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Reduced expression of a rhomboid protease, EhROM1, correlates with changes in the submembrane distribution and size of the Gal/GalNAc lectin subunits in the human protozoan parasite, Entamoeba histolytica by Welter, Brenda H, Walters, Heather A, Temesvari, Lesly A

“…Entamoeba histolytica is a food- and waterborne parasite that causes amebic dysentery and amoebic liver abscesses. Adhesion is one of the most important…”
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Flow cytometric characterization of encystation in Entamoeba invadens by Welter, Brenda H., Sehorn, Michael G., Temesvari, Lesly A.

“…[Display omitted] •Cysts of Entamoeba spp. have attributes that may be tracked by flow cytometry.•Flow cytometry was used to track chitin and cell size in…”
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Phosphorylation of Eukaryotic Initiation Factor-2α during Stress and Encystation in Entamoeba Species by Hendrick, Holland M, Welter, Brenda H, Hapstack, Matthew A, Sykes, Steven E, Sullivan, Jr, William J, Temesvari, Lesly A

“…Entamoeba histolytica is an enteric pathogen responsible for amoebic dysentery and liver abscess. It alternates between the host-restricted trophozoite form…”
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Localization of Phosphatidylinositol 4,5-Bisphosphate to Lipid Rafts and Uroids in the Human Protozoan Parasite Entamoeba histolytica by Koushik, Amrita B, Powell, Rhonda R, Temesvari, Lesly A

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A Genomewide Overexpression Screen Identifies Genes Involved in the Phosphatidylinositol 3-Kinase Pathway in the Human Protozoan Parasite Entamoeba histolytica by Koushik, Amrita B, Welter, Brenda H, Rock, Michelle L, Temesvari, Lesly A

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Eukaryotic Initiation Factor 2α Kinases Regulate Virulence Functions, Stage Conversion, and the Stress Response in Entamoeba invadens by Walters, Heather A, Welter, Brenda H, Moss, Harrison C, Villano, Martha A, Orobio-Hurtado, Ronny, Sullivan, Jr, William J, Temesvari, Lesly A

“…Entamoeba histolytica is a protozoan parasite that causes amoebic dysentery and liver abscess. This pathogen possesses a two-stage life cycle consisting of an…”
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Overexpression of a Mutant Form of EhRabA, a Unique Rab GTPase of Entamoeba histolytica, Alters Endoplasmic Reticulum Morphology and Localization of the Gal/GalNAc Adherence Lectin by Welter, B H, Temesvari, L A

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Localization of Phosphatidylinositol (3,4,5)-Trisphosphate to Phagosomes in Entamoeba histolytica Achieved Using Glutathione S-Transferase- and Green Fluorescent Protein-Tagged Lipid Biosensors by Byekova, Yevgeniya A, Powell, Rhonda R, Welter, Brenda H, Temesvari, Lesly A

“…Entamoeba histolytica is an intestinal protozoan parasite that causes amoebic dysentery and liver abscess. Phagocytosis by the parasite is a critical virulence…”
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Entamoeba histolytica Dmc1 Catalyzes Homologous DNA Pairing and Strand Exchange That Is Stimulated by Calcium and Hop2-Mnd1 by Kelso, Andrew A, Say, Amanda F, Sharma, Deepti, Ledford, LeAnna L, Turchick, Audrey, Saski, Christopher A, King, Ada V, Attaway, Christopher C, Temesvari, Lesly A, Sehorn, Michael G

“…Meiosis depends on homologous recombination (HR) in most sexually reproducing organisms. Efficient meiotic HR requires the activity of the meiosis-specific…”
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Exposure to Host Ligands Correlates with Colocalization of Gal/GalNAc Lectin Subunits in Lipid Rafts and Phosphatidylinositol (4,5)-Bisphosphate Signaling in Entamoeba histolytica by Goldston, Amanda M, Powell, Rhonda R, Koushik, Amrita B, Temesvari, Lesly A

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A genome-wide over-expression screen identifies genes involved in phagocytosis in the human protozoan parasite, Entamoeba histolytica by King, Ada V, Welter, Brenda H, Koushik, Amrita B, Gordon, Lindsay N, Temesvari, Lesly A

“…Functional genomics and forward genetics seek to assign function to all known genes in a genome. Entamoeba histolytica is a protozoan parasite for which…”
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Entamoeba histolytica: Lipid rafts are involved in adhesion of trophozoites to host extracellular matrix components by Mittal, K., Welter, B.H., Temesvari, L.A.

“…Adhesion is an important virulence function for Entamoeba histolytica, the causative agent of amoebic dysentery. Lipid rafts, cholesterol-rich domains,…”
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Involvement of Raft-Like Plasma Membrane Domains of Entamoeba histolytica in Pinocytosis and Adhesion by LAUGHLIN, Richard C, MCGUGAN, Glen C, POWELL, Rhonda R, WELTER, Brenda H, TEMESVARI, Lesly A

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Data on Rad51 amino acid sequences from higher and lower eukaryotic model organisms and parasites by Kelso, Andrew A., Goodson, Steven D., Temesvari, Lesly A., Sehorn, Michael G.

“…This paper contains data related to the research article titled “Characterization of the recombination activities of the Entamoeba histolytica Rad51…”
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Target acquired: transcriptional regulators as drug targets for protozoan parasites by Walters, H.A., Temesvari, L.A.

“…[Display omitted] •New therapeutics are urgently needed to treat parasitic diseases.•Transcription factors lie at the junction of many signalling pathways in…”
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The WASp-like protein scar regulates macropinocytosis, phagocytosis and endosomal membrane flow in Dictyostelium by Seastone, D J, Harris, E, Temesvari, L A, Bear, J E, Saxe, C L, Cardelli, J

“…Scar, a member of the WASp protein family, was discovered in Dictyostelium discoideum during a genetic screen for second-site mutations that suppressed a…”
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Involvement of a Rab8-like protein of Dictyostelium discoideum, Sas1, in the formation of membrane extensions, secretion and adhesion during development by Powell, Rhonda R, Temesvari, Lesly A

“…Department of Biological Sciences, 132 Long Hall, Clemson University, Clemson, SC 29634, USA Correspondence Lesly A. Temesvari LTEMESV{at}clemson.edu…”
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Phosphorylation of eukaryotic initiation factor-2α in response to endoplasmic reticulum and nitrosative stress in the human protozoan parasite, Entamoeba histolytica by Walters, Heather A., Welter, Brenda H., Sullivan, William J., Temesvari, Lesly A.

“…[Display omitted] •DTT induces ER stress in E. histolytica and induces the phosphorylation of eIF-2α.•Nitrosative stress doesn’t induce the phosphorylation of…”
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