Search Results - "Tellis, Meenakshi B."

Repurposing the McoTI-II Rigid Molecular Scaffold in to Inhibitor of 'Papain Superfamily' Cysteine Proteases by Mishra, Manasi, Singh, Vigyasa, Tellis, Meenakshi B, Joshi, Rakesh S, Singh, Shailja

“…Clan C1A or 'papain superfamily' cysteine proteases are key players in many important physiological processes and diseases in most living systems. Novel…”
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Discovery of potential multi-target-directed ligands by targeting host-specific SARS-CoV-2 structurally conserved main protease by Joshi, Rakesh S., Jagdale, Shounak S., Bansode, Sneha B., Shankar, S. Shiva, Tellis, Meenakshi B., Pandya, Vaibhav Kumar, Chugh, Anita, Giri, Ashok P., Kulkarni, Mahesh J.

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in the current COVID-19 pandemic. Worldwide this disease has infected over…”
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Regulation of trehalose metabolism in insects: from genes to the metabolite window by Tellis, Meenakshi B, Kotkar, Hemlata M, Joshi, Rakesh S

“…Abstract Trehalose is a major circulatory sugar in the haemolymph of insects. It provides instant energy and protection against stress. Trehalose metabolism is…”
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Molecular phylogeny, structure modeling and in silico screening of putative inhibitors of aerolysin of Aeromonas hydrophila EUS112 by Yadav, Sunita Kumari, Panwar, Deepak, Singh, Ankita, Tellis, Meenakshi B, Joshi, Rakesh Shamsunder, Dixit, Aparna

“…Aeromonas hydrophila, a Gram-negative bacterium, causes diseases in fish, resulting in excessive loss to the aquaculture industry. Aeromonas is a highly…”
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Functional Diversity of the Lepidopteran ATP-Binding Cassette Transporters by Barve, Pranoti R., Tellis, Meenakshi B., Barvkar, Vitthal T., Joshi, Rakesh S., Giri, Ashok P., Kotkar, Hemlata M.

“…The ATP-binding cassette (ABC) transporter gene family is ubiquitous in the living world. ABC proteins bind and hydrolyze ATP to transport a myriad of…”
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Trehalose transporter-like gene diversity and dynamics enhances stress response and recovery in Helicoverpa armigera by Tellis, Meenakshi B., Chaudhari, Bhagyashri Y., Deshpande, Shweta V., Nikam, Sanika V., Barvkar, Vitthal T., Kotkar, Hemlata M., Joshi, Rakesh S.

“…[Display omitted] •Tret-like sugar transporters (ST) show remarkable sequence and structure diversity.•Diverse HaSTs exhibited spatio-temporal dynamic…”
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Cyclic peptide engineered from phytocystatin inhibitory hairpin loop as an effective modulator of falcipains and potent antimalarial by Mishra, Manasi, Singh, Vigyasa, Tellis, Meenakshi B., Joshi, Rakesh S., Pandey, Kailash C., Singh, Shailja

“…Cystatins are classical competitive inhibitors of C1 family cysteine proteases (papain family). Phytocystatin superfamily shares high sequence homology and…”
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Evolutionary and structure-function analysis elucidates diversification of prokaryotic and eukaryotic trehalases by Tellis, Meenakshi B., Gujar, Nidhi N., Joshi, Rakesh S.

“…Trehalase catalyses the breakdown of trehalose into two glucose moieties and is ubiquitous in all organisms. Here, we provide insights into the enigmatic…”
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Inhibition of Trehalose Synthesis in Lepidoptera Reduces Larval Fitness by Tellis, Meenakshi B., Mohite, Sharada D., Nair, Vineetkumar S., Chaudhari, Bhagyashri Y., Ahmed, Shadab, Kotkar, Hemlata M., Joshi, Rakesh S.

“…Trehalose is synthesized in insects through the trehalose 6‐phosphate synthase and phosphatase (TPS/TPP) pathway. TPP dephosphorylates trehalose 6‐phosphate to…”
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