Search Results - "Tellaoui, Rayan Sleiman"
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Microskeletal stiffness promotes aortic aneurysm by sustaining pathological vascular smooth muscle cell mechanosensation via Piezo1
Published in Nature communications (26-01-2022)“…Mechanical overload of the vascular wall is a pathological hallmark of life-threatening abdominal aortic aneurysms (AAA). However, how this mechanical stress…”
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The Nonproteolytic Intracellular Domain of Membrane-Type 1 Matrix Metalloproteinase Coordinately Modulates Abdominal Aortic Aneurysm and Atherosclerosis in Mice—Brief Report
Published in Arteriosclerosis, thrombosis, and vascular biology (01-10-2022)“…MT1-MMP (membrane-type 1 matrix metalloproteinase, MMP-14) is a transmembrane-anchored protein with an extracellular proteinase domain and a cytoplasmic tail…”
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Abstract 15542: Immuno-Footprint of Myeloid Clusters in Human Abdominal Aortic Aneurysm
Published in Circulation (New York, N.Y.) (08-11-2022)“…Inflammation is a hallmark of abdominal aortic aneurysms (AAA) with central roles ascribed to myeloid lineage effector cells. However, the dynamics of…”
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Abstract 16808: Divergent Mature Vascular Smooth Muscle Cell Fates Are Directed by Platelet-Derived Transcriptomic Codes in Aortic Aneurysms
Published in Circulation (New York, N.Y.) (17-11-2020)“…IntroductionLoss of vascular smooth-muscle cells (vSMC) and subsequent defective replenishment of functional vSMC de novo are pathological hallmarks of…”
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Abstract 155: Divergent Mature Vascular Smooth Muscle Cell Fates Are Directed By Platelet-derived Transcriptomic Codes In Aortic Aneurysms
Published in Arteriosclerosis, thrombosis, and vascular biology (01-05-2022)“…IntroductionLoss of vascular smooth-muscle cells (vSMC) and subsequent defective replenishment of functional vSMC de novo are pathological hallmarks of…”
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