Search Results - "Telford, Karen"

Multicenter, Open-Label, Randomized Phase II Controlled Trial of an Investigational Recombinant Meningococcal Serogroup B Vaccine With and Without Outer Membrane Vesicles, Administered in Infancy by Findlow, Jamie, Borrow, Ray, Snape, Matthew D., Dawson, Tom, Holland, Ann, John, Tessa M., Evans, Anita, Telford, Karen L., Ypma, Ellen, Toneatto, Daniela, Oster, Philipp, Miller, Elizabeth, Pollard, Andrew J.

“…Background. In the absence of an efficacious broadly protective vaccine, serogroup B Neisseria meningitidis (MenB) is the leading cause of bacterial meningitis…”
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Patient Satisfaction With Long-term Sacral Neuromodulation for Fecal Incontinence: Experience From a Single Tertiary Center by Martin, Sarah A, O'Connor, Alexander D, Selvakumar, Deepak, Baraza, Wal, Faulkner, Gemma, Mullins, Domini, Kiff, Edward S, Telford, Karen J, Sharma, Abhiram

“…Sacral neuromodulation is an effective treatment for fecal incontinence in the long term. Efficacy is typically assessed using bowel diary, symptom severity,…”
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The Long-term Outcomes of Sacral Neuromodulation for Fecal Incontinence: A Single-Center Experience by Martin, Sarah, O'Connor, Alexander D, Selvakumar, Deepak, Baraza, Wal, Faulkner, Gemma, Mullins, Domini, Kiff, Edward S, Telford, Karen Jane, Sharma, Abhiram

“…Sacral neuromodulation is an effective treatment for fecal incontinence. To assess the long-term outcomes of sacral neuromodulation and establish the outcomes…”
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Case report and narrative review of the literature: a rare colonic stent failure in a palliative patient by Bressington, Morgan, O’Connor, Alexander, Telford, Karen

“…Introduction With palliative patients, a holistic approach is important. Interventions should minimise length of hospital stay, maximise quality of life, and…”
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Continuous vs stepwise anal acoustic reflectometry: An improved technique for physiological measurement of anal sphincter function? by Heywood, Nick A., Nicholson, James E., Sharma, Abhiram, Kiff, Ed S., Klarskov, Niels, Telford, Karen J.

“…Background Anal acoustic reflectometry (AAR) is a technique for measuring the physiological profile of the anal canal, primarily the internal anal sphincter…”
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Methodologic Validation of a Faster Pelvic Floor Test: Two Randomized Studies in Anal Acoustic Reflectometry by Nicholson, James E, Klarskov, Niels, Heywood, Nick A, Sharma, Abhiram, Kiff, Edward S, Telford, Karen J

“…BACKGROUND:Anal acoustic reflectometry investigates the opening and closing function of the anal canal using reflected sound waves to measure a cross-sectional…”
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Use of Anal Acoustic Reflectometry in the Evaluation of Men With Passive Fecal Leakage by Hornung, Benjamin R, Telford, Karen J, Carlson, Gordon L, Mitchell, Peter J, Klarskov, Niels, Kiff, Edward S

“…Men with passive fecal leakage represent a distinct clinical entity in which the pathophysiology remains unclear. Standard anorectal investigations fail to…”
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Percutaneous tibial nerve stimulation versus sacral nerve stimulation for the treatment of faecal incontinence by O'Connor, Alexander, Reynolds, Elizabeth, Molyneux, Clare, Vasant, Dipesh H, Sharma, Abhiram, Faulkner, Gemma, McLaughlin, John, Kiff, Edward, Telford, Karen

“…Faecal incontinence (FI) is a common condition with a significant impact on quality of life (QoL). Neuromodulation treatments delivered by members of the…”
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The short-term effects of posterior tibial nerve stimulation on anorectal physiology in patients with faecal incontinence: a single centre experience by Heywood, Nick A., Pearson, James S., Nicholson, James E., Molyneux, Clare, Sharma, Abhiram, Kiff, Edward S., Whorwell, Peter J., Telford, Karen J.

“…Background: Posterior tibial nerve stimulation (PTNS) is a novel treatment for patients with faecal incontinence (FI) and may be effective in selected…”
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Anal Acoustic Reflectometry: A New Reproducible Technique Providing Physiological Assessment of Anal Sphincter Function by Mitchell, Peter J, Klarskov, Niels, Telford, Karen J, Hosker, Gordon L, Lose, Gunnar, Kiff, Edward S

“…BACKGROUND:Anal acoustic reflectometry is a new technique of assessing anal sphincter function. Five new variables reflecting anal canal function are…”
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Viscoelastic Assessment of Anal Canal Function Using Acoustic Reflectometry: A Clinically Useful Technique by Mitchell, Peter J, Klarskov, Niels, Telford, Karen J, Hosker, Gordon L, Lose, Gunnar, Kiff, Edward S

“…BACKGROUND:Anal acoustic reflectometry is a new reproducible technique that allows a viscoelastic assessment of anal canal function. Five new variables…”
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Complete circumferential rectal ulceration and haemorrhage secondary to the use of a faecal management system by Shaker, Hudhaifah, Maile, Edward J., Telford, Karen J.

“…This structured case report is a brief case report describing an episode of complete circumferential rectal ulceration and haemorrhage secondary to the use of…”
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Is Permanent Sacral nerve Stimulation Implantation Under Local Anaesthesia Feasible and Effective? by Sara Faily, Moez Zeiton, James Nicholson, Karen Telford, Abhiram Sharma

“…Background Sacral nerve stimulation (SNS) is a minimally invasive surgical technique that plays an important role in the treatment of disorders of the bladder…”
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Anterior anal sphincter repair can be of long term benefit: a 12-year case cohort from a single surgeon by Grey, Benjamin R, Sheldon, Rowena R, Telford, Karen J, Kiff, Edward S

“…Early surgical results of anterior sphincter repair for faecal incontinence can be good, but in the longer term are often disappointing. This study aimed to…”
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Trans-anal irrigation should be offered to patients with severe bowel dysfunction by Byrne, Caroline Mary, Sharma, Abhiram, Telford, Karen

“…Byrne et al discuss trans-anal irrigation (TAI) which should be offered to patients with severe bowel dysfunction. Severe bowel dysfunction can present with…”
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Anal sphincter function in rectal intussusception and high and low "take-off" external rectal prolapse-A prospective observational study by O'Connor, Alexander, Byrne, Caroline M, Heywood, Nick, Davenport, Matthew, Klarskov, Niels, Sharma, Abhiram, Kiff, Edward, Telford, Karen

“…Rectal intussusception (RI) and external rectal prolapse (ERP) are associated with anal sphincter dysfunction. The aim of this study was to examine sphincter…”
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Current and future perspectives on the utility of provocative tests of anal sphincter function: A state‐of‐the‐art summary by O'Connor, Alexander, Byrne, Caroline M., Vasant, Dipesh H., Sharma, Abhiram, Liao, Donghua, Klarskov, Niels, Kiff, Edward S., Telford, Karen

“…Background The maintenance of fecal continence depends upon coordinated interactions between the pelvic floor, anorectum, and anal sphincter complex…”
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A comparison of function lumen imaging probe measurements of anal sphincter function in fecal incontinence by O'Connor, Alexander, Liao, Donghua, Drewes, Asbjørn Mohr, Sharma, Abhiram, Vasant, Dipesh H., McLaughlin, John, Kiff, Edward, Telford, Karen

“…Background The functional lumen imaging probe (FLIP) is a test of anal sphincter distensibility under evaluation by specialist centers. Two measurement…”
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Seizing the opportunity to improve patient care: pelvic floor services in 2021 and beyond by Pakzad, Mahreen, Telford, Karen, Ward, Karen, Keighley, Michael

“…Patients requiring pelvic floor and functional urological, gynaecological and coloproctological surgery were viewed as a low priority even before COVID-19. A…”
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Sacral nerve stimulation—hidden costs (uncovered) by Zeiton, M., Faily, Sara, Nicholson, James, Telford, Karen, Sharma, Abhiram

“…Aim The aim of this study is to determine the occurrence of surgical revision in a cohort of patients treated with sacral nerve stimulation (SNS) for faecal…”
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