Search Results - "Telen, Dries"

Robust multi-objective dynamic optimization of chemical processes using the Sigma Point method by Vallerio, Mattia, Telen, Dries, Cabianca, Lorenzo, Manenti, Flavio, Impe, Jan Van, Logist, Filip

“…Dynamic optimization solutions largely rely on the accuracy of the underlying mathematical models. However, these models only represent an approximation of the…”
Get full text

Towards quality by design in pharmaceutical manufacturing: modelling and control of air jet mills by Bhonsale, Satyajeet, Telen, Dries, Stokbroekx, Bard, Van Impe, Jan

“…Milling is an important step in pharmaceutical manufacturing as it not only determines the final formulation of the drug product, but also influences the…”
Get full text

Optimal experiment design under parametric uncertainty: A comparison of a sensitivities based approach versus a polynomial chaos based stochastic approach by Nimmegeers, Philippe, Bhonsale, Satyajeet, Telen, Dries, Van Impe, Jan

“…•Efficient approach for stochastic OED based on polynomial chaos expansion.•Comparison of stochastic OED with sensitivities based OED formulation.•Robustness…”
Get full text

Dynamic optimization of biological networks under parametric uncertainty by Nimmegeers, Philippe, Telen, Dries, Logist, Filip, Impe, Jan Van

“…Micro-organisms play an important role in various industrial sectors (including biochemical, food and pharmaceutical industries). A profound insight in the…”
Get full text

Effect of chyme viscosity and nutrient feedback mechanism on gastric emptying by Moxon, Thomas E., Nimmegeers, Philippe, Telen, Dries, Fryer, Peter J., Van Impe, Jan, Bakalis, Serafim

“…•Gastric emptying rate linked to intestinal bioaccessability by feedback mechanism.•Gastric secretion model links the secretion rate to the gastric…”
Get full text

Comparison of numerical solution strategies for population balance model of continuous cone mill by Bhonsale, Satyajeet S., Telen, Dries, Stokbroekx, Bard, Van Impe, Jan

“…Population balance models are routinely used for modeling particulate processes involving breakage, agglomeration, crystallisation, etc. In this study, a…”
Get full text

A process simulator interface for multiobjective optimization of chemical processes by Muñoz López, Carlos André, Telen, Dries, Nimmegeers, Philippe, Cabianca, Lorenzo, Logist, Filip, Van Impe, Jan

“…•A novel interface for gradient-based multiobjective optimization of processes.•Multiple relevant tradeoffs in the Pareto front can be evaluated for complex…”
Get full text

Interactive Multi‐objective Dynamic Optimization of Bioreactors under Parametric Uncertainty by Nimmegeers, Philippe, Vallerio, Mattia, Telen, Dries, Impe, Jan, Logist, Filip

“…Model‐based optimization techniques play a key role in achieving a sustainable operation of biochemical processes. Models are an approximation of the real…”
Get full text

Identifiability of large-scale non-linear dynamic network models applied to the ADM1-case study by Nimmegeers, Philippe, Lauwers, Joost, Telen, Dries, Logist, Filip, Impe, Jan Van

“…•The structural identifiability of a large-scale biochemical model is investigated.•The probabilistic algorithm of Sedoglavic is adapted to handle…”
Get full text

A differentiable reformulation for E-optimal design of experiments in nonlinear dynamic biosystems by Telen, Dries, Van Riet, Nick, Logist, Flip, Van Impe, Jan

“…•Reformulation strategy for minimum eigenvalue maximization in optimal experiment design.•Nonlinear matrix inequality is enforced by Sylverster’s…”
Get full text

An economic objective for the optimal experiment design of nonlinear dynamic processes by Houska, Boris, Telen, Dries, Logist, Filip, Diehl, Moritz, Van Impe, Jan F.M.

“…State-of-the-art formulations of optimal experiment design problems are typically based on a design criterion which allows us to optimize a scalar map of the…”
Get full text

Optimal experiment design for nonlinear dynamic (bio)chemical systems using sequential semidefinite programming by Telen, Dries, Logist, Filip, Quirynen, Rien, Houska, Boris, Diehl, Moritz, Van Impe, Jan

“…Optimal experiment design (OED) for parameter estimation in nonlinear dynamic (bio)chemical processes is studied in this work. To reduce the uncertainty in an…”
Get full text

Multi-objective optimal control of dynamic bioprocesses using ACADO Toolkit by Logist, Filip, Telen, Dries, Houska, Boris, Diehl, Moritz, Van Impe, Jan

“…The optimal design and operation of dynamic bioprocesses gives in practice often rise to optimisation problems with multiple and conflicting objectives. As a…”
Get full text

On the implementation of generalized polynomial chaos in dynamic optimization under stochastic uncertainty: a user perspective by Bhonsale, Satyajeet, Nimmegeers, Philippe, Telen, Dries, Paulson, Joel A., Mesbah, Ali, Van Impe, Jan

“…Throughout the past century, numerous frameworks have been presented to address different types of uncertainty in model-based (dynamic) optimization. One of…”
Get full text

Optimal experiment design under process noise using Riccati differential equations by Telen, D., Houska, B., Logist, F., Van Derlinden, E., Diehl, M., Van Impe, J.

“…► Novel numerical method for computing variance–covariance matrix with Riccati-based ordinary differential equations. ► Process noise is taken into account in…”
Get full text

Reformulating the Minimum Eigenvalue Maximization in Optimal Experiment Design of Nonlinear Dynamic Biosystems by Telen, Dries, Van Riet, Nick, Logist, Filip, Van Impe, Jan

“…Experiments that yield as much information as possible are desired for estimating parameters in nonlinear dynamic bioprocesses. Techniques for optimal…”
Get full text

Investigating practical aspects of the exergy based multi-objective optimization of chemical processes by Muñoz, Carlos A., Telen, Dries, Nimmegeers, Philippe, Cabianca, Lorenzo, Logist, Filip, Van Impe, Jan

“…When optimizing chemical processes, conflicting objectives are often present (Logist et al, 2011). In industry, the trend towards sustainable development…”
Get full text

Robust multi-objective optimal control of dynamic biological networks by Nimmegeers, Philippe, Telen, Dries, Beetens, Mickey, Logist, Filip, Van Impe, Jan

“…For a sustainable biochemical industry, an improved design and operation of processes with respect to economic, environmental and safety aspects is vital. In…”
Get full text

SolACE: An Open Source Package for Nolinear Model Predictive Control and State Estimation for (Bio)Chemical Processes by Bhonsale, Satyajeet S., Vallerio, Mattia, Telen, Dries, Vercammen, Dominique, Logist, Filip, van Impe, Jan

“…In spite of the wide spread use of Nonlinear Model Predictive Control (NMPC) in large chemical companies, the small and medium enterprises (SMEs) remain…”
Get full text

GASDS: a Kinetic-Based Package for Biomass and Coal Gasification by L. Cabianca, A. Bassani, A.F. Amaral, F. Rossi, G. Bozzano, E. Ranzi, D. Telen, F. Logist, J. Van Impe, F. Manenti

“…In this paper, a simulation package called GASDS is introduced. It is particularly suited to evaluate the pyrolysis, gasification and combustion of biomass and…”
Get full text