Search Results - "Telegin, G. B."
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A new mouse unilateral model of diffuse alveolar damage of the lung
Published in Inflammation research (01-06-2022)“…Objective and design The existing biological models of diffuse alveolar damage (DAD) in mice have many shortcomings. To offset these shortcomings, we have…”
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2
BarnaseBarstar-guided two-step targeting approach for drug delivery to tumor cells in vivo
Published in Journal of controlled release (10-12-2021)“…For precise ligation of a targeting and cytotoxic moiety, the use of Barnase-Barstar pair as a molecular glue is proposed for the first time. Targeting was…”
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3
Peripherally Applied Synthetic Peptide isoAsp7-Aβ(1-42) Triggers Cerebral β-Amyloidosis
Published in Neurotoxicity research (01-10-2013)“…Intracerebral and intraperitoneal inoculation with β-amyloid-rich brain extracts originating from patients with Alzheimer’s disease as well as intracerebral…”
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4
Proof-of-Concept Study of Liposomes with a Set of SARS-CoV-2 Viral Peptidic T-Cell Epitopes as a Vaccine
Published in Russian journal of bioorganic chemistry (01-12-2022)“…Potential nonameric epitopes of CD8 + T lymphocytes were selected from the composition of structural, accessory, and nonstructural proteins of the SARS-CoV-2…”
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Barnase-barstar Specific Interaction Regulates Car-T Cells Cytotoxic Activity toward Malignancy
Published in Doklady. Biochemistry and biophysics (01-02-2023)“…The development of CAR-T specific therapy made a revolution in modern oncology. Despite the pronounced therapeutic effects, this novel approach displayed…”
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6
Experimental Models of Spinal Cord Injury in Laboratory Rats
Published in Actanaturae (01-07-2018)“…Pathologies associated with spinal cord injury are some of the leading diseases in the world. The search for new therapeutic agents and 3D biodegradable…”
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Cytokine profile as a marker of cell damage and immune dysfunction after spinal cord injury
Published in Actanaturae (01-07-2020)“…This study reviews the findings of recent experiments designed to investigate the cytokine profile after a spinal cord injury. The role played by key cytokines…”
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Surgical Simulation of a Posttraumatic Spinal Cord Glial Scar in Rats
Published in Actanaturae (01-07-2019)“…We developed and verified an original, minimally invasive method for surgical simulation of a posttraumatic spinal cord glial scar in rats. The model is…”
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Analysis of Immunogenicity of Intracellular CTAR Fragments of Epstein—Barr Virus Latent Phase Protein LMP1
Published in Bulletin of experimental biology and medicine (01-10-2017)“…Intracellular fragments of latent phase protein LMP1 of Epstein—Barr virus, denoted as CTAR1/2/3, can trigger a variety of cell cascades and contribute to the…”
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Studying the Specific Activity of the Amide Form of HLDF-6 Peptide using the Transgenic Model of Alzheimer's Disease
Published in Actanaturae (01-07-2017)“…The neuroprotective and nootropic activities of the amide form (AF) of the HLDF-6 peptide (TGENHR-NH ) were studied in transgenic mice of the…”
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Specific Depletion of Myelin-Reactive B Cells via BCR-Targeting
Published in Actanaturae (01-04-2015)“…B cells play a crucial role in the development and pathogenesis of systemic and organ-specific autoimmune diseases. Autoreactive B cells not only produce…”
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12
Antibody proteases: induction of catalytic response
Published in Biochemistry (Moscow) (01-10-2002)“…Most of the data accumulated throughout the years on investigation of catalytic antibodies indicate that their production increases on the background of…”
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13
Modeling myocardial infarction in mice: methodology, monitoring, pathomorphology
Published in Actanaturae (01-01-2011)“…Myocardial infarction is one of the most serious and widespread diseases in the world. In this work, a minimally invasive method for simulating myocardial…”
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14
Catalytic activity of autoantibodies toward myelin basic protein correlates with the scores on the multiple sclerosis expanded disability status scale
Published in Immunology Letters (28-02-2006)“…Autoantibodies toward myelin basic protein (MBP) evidently emerge in sera and cerebrospinal fluid of the patients with multiple sclerosis (MS), as well as in a…”
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15
New experimental model of multiple myeloma
Published in Bulletin of experimental biology and medicine (01-06-2001)“…NSO/1 (P3x63Ay 8Ut) and SP20 myeloma cells were inoculated to BALB/c OlaHsd mice. NSO/1 cells allowed adequate stage-by-stage monitoring of tumor development…”
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Induction of a Protein-Targeted Catalytic Response in Autoimmune Prone Mice: Antibody-Mediated Cleavage of HIV-1 Glycoprotein GP120
Published in Biochemistry (Easton) (10-01-2006)“…We have induced a polyclonal IgG that degrades the HIV-1 surface antigen, glycoprotein gp120, by taking advantage of the susceptibility of SJL mice to a…”
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Catalytic antibodies in clinical and experimental pathology: human and mouse models
Published in Journal of immunological methods (01-11-2002)“…Most of the data accumulated through studies on natural catalytic autoantibodies indicate that production scales up markedly in pathological abnormalities. We…”
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Substrate specificity of catalytic autoantibodies in neurodegenerative processes
Published in Doklady. Biochemistry and biophysics (01-04-2007)“…(ProQuest: Abstract omitted; see image)[PUBLICATION ABSTRACT]…”
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Surgical Simulation of a Posttraumatic Spinal Cord Glial Scar in Rats
Published in Actanaturae (01-09-2019)Get full text
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20
Natural antibody catalytic activities in mice with autoimmune disorders
Published in Doklady. Biochemistry (01-11-2000)“…(ProQuest: Abstract omitted; see image)[PUBLICATION ABSTRACT]…”
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