Search Results - "Telaprolu, Krishna"
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Evaluation of Quantum Dot Skin Penetration in Porcine Skin: Effect of Age and Anatomical Site of Topical Application
Published in Skin pharmacology and physiology (01-01-2019)“…Pig skin is a widely acknowledged surrogate for human skin for in vitro/ex vivo skin penetration studies with application for small molecules and nanosystems…”
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Human Skin Drug Metabolism: Relationships between Methyl Salicylate Metabolism and Esterase Activities in IVPT Skin Membranes
Published in Metabolites (01-08-2023)“…The presence of esterase enzymes in human skin and their role in drug metabolism has been reported, but their distribution in the various skin layers and the…”
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Vegetable moisturizing raw material from “Caatinga” Brazilian biome: safety and efficacy evaluations of O/W cosmetic emulsions containing Kalanchoe brasiliensis extract
Published in Brazilian Journal of Pharmaceutical Sciences (01-01-2018)“…The purpose of this study was to evaluate the safety of Kalanchoe brasiliensis extract, followed by the development of an oil in water emulsion containing the…”
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Development and verification of mechanistic vaginal absorption and metabolism model to predict systemic exposure after vaginal ring and gel application
Published in British journal of clinical pharmacology (01-06-2024)“…Aims The current work describes the development of mechanistic vaginal absorption and metabolism model within Simcyp Simulator to predict systemic…”
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Skin models for the testing of transdermal drugs
Published in Clinical pharmacology: advances and applications (01-01-2016)“…The assessment of percutaneous permeation of molecules is a key step in the evaluation of dermal or transdermal delivery systems. If the drugs are intended for…”
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Mechanistic Model for Drug Release from PLGA-Based Biodegradable Implants for In Vitro Release Testing: Development and Validation
Published in ACS applied bio materials (18-11-2024)“…Several factors can affect drug release from polylactide coglycolide (PLGA)-based formulations, including polymer and drug properties, formulation components,…”
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Using a simple equation to predict the microporation-enhanced transdermal drug flux
Published in European journal of pharmaceutics and biopharmaceutics (01-06-2018)“…[Display omitted] The mathematical model describing drug flux through microporated skin was previously developed. Based on this model, two mathematical…”
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Microcontroller based automation of variable electronic speed governor
Published in 2009 IEEE International Conference on Vehicular Electronics and Safety (ICVES) (01-11-2009)“…This paper is researched and documented so as to be realizable in the form of a practical solution for the impending traffic problem presently observed in…”
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