Search Results - "Teku, Gabriel"

Pan-cancer analysis of neoepitopes by Teku, Gabriel N., Vihinen, Mauno

“…Somatic variations are frequent and important drivers in cancers. Amino acid substitutions can yield neoantigens that are detected by the immune system…”
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Simulation of the dynamics of primary immunodeficiencies in CD4+ T-cells by Teku, Gabriel N, Vihinen, Mauno

“…Primary immunodeficiencies (PIDs) form a large and heterogeneous group of mainly rare disorders that affect the immune system. T-cell deficiencies account for…”
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TNF-α and α-synuclein fibrils differently regulate human astrocyte immune reactivity and impair mitochondrial respiration by Russ, Kaspar, Teku, Gabriel, Bousset, Luc, Redeker, Virginie, Piel, Sara, Savchenko, Ekaterina, Pomeshchik, Yuriy, Savistchenko, Jimmy, Stummann, Tina C., Azevedo, Carla, Collin, Anna, Goldwurm, Stefano, Fog, Karina, Elmer, Eskil, Vihinen, Mauno, Melki, Ronald, Roybon, Laurent

“…Here, we examine the cellular changes triggered by tumor necrosis factor alpha (TNF-α) and different alpha-synuclein (αSYN) species in astrocytes derived from…”
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FGF family members differentially regulate maturation and proliferation of stem cell-derived astrocytes by Savchenko, Ekaterina, Teku, Gabriel N., Boza-Serrano, Antonio, Russ, Kaspar, Berns, Manon, Deierborg, Tomas, Lamas, Nuno J., Wichterle, Hynek, Rothstein, Jeffrey, Henderson, Christopher E., Vihinen, Mauno, Roybon, Laurent

“…The glutamate transporter 1 (GLT1) is upregulated during astrocyte development and maturation in vivo and is vital for astrocyte function. Yet it is expressed…”
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Identification of core T cell network based on immunome interactome by Teku, Gabriel N, Ortutay, Csaba, Vihinen, Mauno

“…Data-driven studies on the dynamics of reconstructed protein-protein interaction (PPI) networks facilitate investigation and identification of proteins…”
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Simulation of the Dynamics of Primary Immunodeficiencies in B Cells by Teku, Gabriel Ndipagbornchi, Vihinen, Mauno

“…Primary immunodeficiencies (PIDs) are a group of over 300 hereditary, heterogeneous, and mainly rare disorders that affect the immune system. Various aspects…”
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NF-Y influences directionality of transcription from the bidirectional Mrps12/ Sarsm promoter in both mouse and human cells by Zanotto, Ernesto, Häkkinen, Antti, Teku, Gabriel, Shen, Bairong, Ribeiro, Andre S., Jacobs, Howard T.

“…The bidirectional mammalian promoter for mitoribosomal protein S12 (Mrps12) and mitochondrial seryl-tRNA ligase (Sarsm) contains an array of four CCAAT boxes…”
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Insertion of the CXXC domain of KMT2A into YAP1: An unusual mechanism behind the formation of a chimeric oncogenic protein by Teku, Gabriel, Nilsson, Jenny, Magnusson, Linda, Sydow, Saskia, Flucke, Uta, Puls, Florian, Mitra, Shamik, Mertens, Fredrik

“…Most neoplasia-associated gene fusions are formed through the fusion of the 5'-part of one gene with the 3'-part of another. We here describe a unique…”
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Parkinson's disease and multiple system atrophy patient iPSC-derived oligodendrocytes exhibit alpha-synuclein-induced changes in maturation and immune reactive properties by Azevedo, Carla, Teku, Gabriel, Pomeshchik, Yuriy, Reyes, Juan F, Chumarina, Margarita, Russ, Kaspar, Savchenko, Ekaterina, Hammarberg, Anna, Lamas, Nuno Jorge, Collin, Anna, Gouras, Gunnar K, Klementieva, Oxana, Hallbeck, Martin, Taipa, Ricardo, Vihinen, Mauno, Roybon, Laurent

“…SignificanceOur results demonstrate the existence of early cellular pathways and network alterations in oligodendrocytes in the alpha-synucleinopathies…”
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Circulating plasma microRNAs in systemic sclerosis-associated pulmonary arterial hypertension by Wuttge, Dirk M, Carlsen, Anting L, Teku, Gabriel, Wildt, Marie, Rådegran, Göran, Vihinen, Mauno, Heegaard, Niels H H, Hesselstrand, Roger

“…Abstract Objectives SSc-associated pulmonary arterial hypertension (SSc-APAH) is a late but devastating complication of SSc. Early identification of SSc-APAH…”
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Specific autoantibody profiles and disease subgroups correlate with circulating micro-RNA in systemic sclerosis by Wuttge, Dirk M, Carlsen, Anting Liu, Teku, Gabriel, Steen, Samantha O, Wildt, Marie, Vihinen, Mauno, Hesselstrand, Roger, Heegaard, Niels H H

“…To evaluate the expression profiles of cell-free plasma miRNAs in SSc and to characterize their correlation with disease subgroups (lcSSc and dcSSc) and with…”
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