Search Results - "Tekinay, Ayse B"

Intracellular Accumulation of Gold Nanoparticles Leads to Inhibition of Macropinocytosis to Reduce the Endoplasmic Reticulum Stress by Gunduz, Nuray, Ceylan, Hakan, Guler, Mustafa O., Tekinay, Ayse B.

“…Understanding the toxicity of nanomaterials remains largely limited to acute cellular response, i.e., short-term in vitro cell-death based assays, and analyses…”
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Selective adhesion and growth of vascular endothelial cells on bioactive peptide nanofiber functionalized stainless steel surface by Ceylan, Hakan, Tekinay, Ayse B, Guler, Mustafa O

“…Abstract Metal-based scaffolds such as stents are the most preferred treatment methods for coronary artery disease. However, impaired endothelialization on the…”
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Heparin mimetic peptide nanofiber gel promotes regeneration of full thickness burn injury by Yergoz, Fatih, Hastar, Nurcan, Cimenci, Cagla Eren, Ozkan, Alper Devrim, Tekinay, Turgay, Guler, Mustafa O, Tekinay, Ayse B

“…Abstract Burn injuries are one of the most common types of trauma worldwide, and their unique physiology requires the development of specialized therapeutic…”
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Growth Factor Binding on Heparin Mimetic Peptide Nanofibers by Mammadov, Rashad, Mammadov, Busra, Guler, Mustafa O, Tekinay, Ayse B

“…Immobilization of growth factors in scaffolds is important for controlling their dose and bioactivity for regenerative medicine applications. Although numerous…”
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Supramolecular GAG-like Self-Assembled Glycopeptide Nanofibers Induce Chondrogenesis and Cartilage Regeneration by Ustun Yaylaci, Seher, Sardan Ekiz, Melis, Arslan, Elif, Can, Nuray, Kilic, Erden, Ozkan, Huseyin, Orujalipoor, Ilghar, Ide, Semra, Tekinay, Ayse B, Guler, Mustafa O

“…Glycosaminoglycans (GAGs) and glycoproteins are vital components of the extracellular matrix, directing cell proliferation, differentiation, and migration and…”
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Heparin Mimetic Peptide Nanofibers Promote Angiogenesis by Mammadov, Rashad, Mammadov, Busra, Toksoz, Sila, Aydin, Bahri, Yagci, Ramazan, Tekinay, Ayse B, Guler, Mustafa O

“…New blood vessel formation (angiogenesis) is one of the most important processes required for functional tissue formation. Induction of angiogenesis is usually…”
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Mitochondrial serine protease HTRA2 p.G399S in a kindred with essential tremor and Parkinson disease by Gulsuner, Hilal Unal, Gulsuner, Suleyman, Mercan, Fatma Nazli, Onat, Onur Emre, Walsh, Tom, Shahin, Hashem, Lee, Ming K., Dogu, Okan, Kansu, Tulay, Topaloglu, Haluk, Elibol, Bulent, Akbostanci, Cenk, King, Mary-Claire, Ozcelik, Tayfun, Tekinay, Ayse B.

“…Significance Essential tremor is one of the most frequent movement disorders of humans, but its causes remain largely unknown. In a six-generation family with…”
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Self-Assembled Proteins and Peptides as Scaffolds for Tissue Regeneration by Loo, Yihua, Goktas, Melis, Tekinay, Ayse B., Guler, Mustafa O., Hauser, Charlotte A. E., Mitraki, Anna

“…Self‐assembling proteins and peptides are increasingly gaining interest for potential use as scaffolds in tissue engineering applications. They self‐organize…”
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Glycosaminoglycan-Mimetic Signals Direct the Osteo/Chondrogenic Differentiation of Mesenchymal Stem Cells in a Three-Dimensional Peptide Nanofiber Extracellular Matrix Mimetic Environment by Arslan, Elif, Guler, Mustafa O, Tekinay, Ayse B

“…Recent efforts in bioactive scaffold development focus strongly on the elucidation of complex cellular responses through the use of synthetic systems…”
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Alkaline Phosphatase-Mimicking Peptide Nanofibers for Osteogenic Differentiation by Gulseren, Gulcihan, Yasa, I. Ceren, Ustahuseyin, Oya, Tekin, E. Deniz, Tekinay, Ayse B, Guler, Mustafa O

“…Recognition of molecules and regulation of extracellular matrix synthesis are some of the functions of enzymes in addition to their catalytic activity. While a…”
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Cellular Internalization of Therapeutic Oligonucleotides by Peptide Amphiphile Nanofibers and Nanospheres by Mumcuoglu, Didem, Sardan Ekiz, Melis, Gunay, Gokhan, Tekinay, Turgay, Tekinay, Ayse B, Guler, Mustafa O

“…Oligonucleotides are promising drug candidates due to the exceptionally high specificity they exhibit toward their target DNA and RNA sequences. However, their…”
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Peptide Nanofiber System for Sustained Delivery of Anti-VEGF Proteins to the Eye Vitreous by Yaylaci, Seher, Dinç, Erdem, Aydın, Bahri, Tekinay, Ayse B, Guler, Mustafa O

“…Ranibizumab is a recombinant VEGF-A antibody used to treat the wet form of age-related macular degeneration. It is intravitreally administered to ocular…”
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Bioactive Supramolecular Peptide Nanofibers for Regenerative Medicine by Arslan, Elif, Garip, I. Ceren, Gulseren, Gulcihan, Tekinay, Ayse B., Guler, Mustafa O.

“…Recent advances in understanding of cell–matrix interactions and the role of the extracellular matrix (ECM) in regulation of cellular behavior have created new…”
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role for LYNX2 in anxiety-related behavior by Tekinay, Ayse B, Nong, Yi, Miwa, Julie M, Lieberam, Ivo, Ibanez-Tallon, Ines, Greengard, Paul, Heintz, Nathaniel

“…Anxiety disorders are the most prevalent mental disorders in developed societies. Although roles for the prefrontal cortex, amygdala, hippocampus and…”
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Multi-Domain Short Peptide Molecules for in Situ Synthesis and Biofunctionalization of Gold Nanoparticles for Integrin-Targeted Cell Uptake by Unal Gulsuner, Hilal, Ceylan, Hakan, Guler, Mustafa O, Tekinay, Ayse B

“…We describe design and synthesis model of multidomain (modular) peptides (MDPs), which direct a reaction cascade coupling the synthesis and surface…”
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Atomic force microscopy for the investigation of molecular and cellular behavior by Ozkan, Alper D., Topal, Ahmet E., Dana, Aykutlu, Guler, Mustafa O., Tekinay, Ayse B.

“…The present review details the methods used for the measurement of cells and their exudates using atomic force microscopy (AFM) and outlines the general…”
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Basal Lamina Mimetic Nanofibrous Peptide Networks for Skeletal Myogenesis by Yasa, I. Ceren, Gunduz, Nuray, Kilinc, Murat, Guler, Mustafa O., Tekinay, Ayse B.

“…Extracellular matrix (ECM) is crucial for the coordination and regulation of cell adhesion, recruitment, differentiation and death. Therefore, equilibrium…”
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Chondrogenic Differentiation of Mesenchymal Stem Cells on Glycosaminoglycan-Mimetic Peptide Nanofibers by Yaylaci, Seher Ustun, Sen, Merve, Bulut, Ozlem, Arslan, Elif, Guler, Mustafa O, Tekinay, Ayse B

“…Glycosaminoglycans (GAGs) are important extracellular matrix components of cartilage tissue and provide biological signals to stem cells and chondrocytes for…”
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Recent Advances in Bioactive 1D and 2D Carbon Nanomaterials for Biomedical Applications by Erol, Ozlem, Uyan, Idil, Hatip, Meryem, Yilmaz, Canelif, Tekinay, Ayse B, Guler, Mustafa O

“…Abstract One-dimensional (1D) carbon nanotubes (CNTs) and the two-dimensional (2D) graphene represent the most widely studied allotropes of carbon. Due to…”
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Reply to Tzoulis et al: Genetic and clinical heterogeneity of essential tremor by Gulsuner, Hilal Unal, Gulsuner, Suleyman, Mercan, Fatma Nazli, Onat, Onur Emre, Walsh, Tom, Shahin, Hashem, Lee, Ming K., Dogu, Okan, Kansu, Tulay, Topaloglu, Haluk, Elibol, Bulent, Akbostanci, Cenk, King, Mary-Claire, Ozcelik, Tayfun, Tekinay, Ayse B.

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