Search Results - "Tekie, Farnaz Sadat Mirzazadeh"
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Controlling evolution of protein corona: a prosperous approach to improve chitosan-based nanoparticle biodistribution and half-life
Published in Scientific reports (15-06-2020)“…Protein corona significantly affects in vivo fate of nanoparticles including biodistribution and half-life. Without manipulating the physicochemical properties…”
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The Antitumor Effect of Topotecan Loaded Thiolated Chitosan-Dextran Nanoparticles for Intravitreal Chemotherapy: A Xenograft Retinoblastoma Model
Published in Journal of ophthalmic & vision research (01-01-2023)“…This research intended to fabricate the thiolated chitosan-dextran nanoparticles (NPs) containing topotecan (TPH-CMD-TCS-NPs) to assess the ability of NPs in…”
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Carboxymethyl dextran‐trimethyl chitosan coated superparamagnetic iron oxide nanoparticles: An effective siRNA delivery system for HIV‐1 Nef
Published in Journal of cellular physiology (01-11-2019)“…Gene therapy, including small interfering RNA (siRNA) technology, is one of the leading strategies that help to improve the outcomes of the current therapeutic…”
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Intracellular delivery of anticancer agents using dual responsive nanomicelles synthesized via RAFT polymerization
Published in European polymer journal (17-10-2023)“…[Display omitted] •Diselenide core crosslinked micelles were developed for docetaxel (DTX) delivery, combining synergistic antitumor chemotherapy with…”
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Inhibition of HIF-1α/EP4 axis by hyaluronate-trimethyl chitosan-SPION nanoparticles markedly suppresses the growth and development of cancer cells
Published in International journal of biological macromolecules (15-01-2021)“…Increased expression of Hypoxia-inducible factor-1α (HIF-1α) in the tumor microenvironment, mainly due to tumor growth, plays a major role in the growth of…”
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Design and fabrication of dual‐targeted delivery system based on gemcitabine‐conjugated human serum albumin nanoparticles
Published in Chemical biology & drug design (01-08-2020)“…Dual‐targeted drug delivery system has established their reputation as potent vehicles for cancer chemotherapies. Herein, gemcitabine (Gem) was conjugated to…”
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Hydrogels Composed of Cyclodextrin Inclusion Complexes with PLGA-PEG-PLGA Triblock Copolymers as Drug Delivery Systems
Published in AAPS PharmSciTech (01-02-2014)“…Although conventional pharmaceuticals have many drug dosage forms on the market, the development of new therapeutic molecules and the low efficacy of instant…”
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In-vivo study of naltrexone hydrochloride release from an in-situ forming PLGA-PEG-PLGA system in the rabbit
Published in Journal of drug delivery science and technology (01-12-2016)“…A thermosensitive hydrogel of PLGA-PEG-PLGA triblock synthesized via ring opening polymerization using microwave irradiation method was used to control the…”
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Sustained release drug delivery using supramolecular hydrogels of the triblock copolymer PCL–PEG–PCL and α-cyclodextrin
Published in Journal of sol-gel science and technology (2014)“…Supramolecular hydrogels (SMGel) have attracted much attention as a drug and gene delivery system in recent years. In this study, SMGels based on the tri-block…”
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Preparation and analysis of a sustained drug delivery system by PLGA–PEG–PLGA triblock copolymers
Published in Polymer bulletin (Berlin, Germany) (01-08-2012)“…Traditional drug delivery systems that are based on multiple dosing are usually accompanied by many shortcomings, including unwanted fluctuations in the plasma…”
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Thiolated carboxymethyl dextran as a nanocarrier for colon delivery of hSET1 antisense: In vitro stability and efficiency study
Published in Materials Science & Engineering C (01-05-2016)“…Gene therapy is an optimistic approach in cancer treatment. However, for efficient delivery of gene materials, designing an appropriate vector is necessary…”
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Glutathione responsive chitosan-thiolated dextran conjugated miR-145 nanoparticles targeted with AS1411 aptamer for cancer treatment
Published in Carbohydrate polymers (01-12-2018)“…[Display omitted] •TD-miR redox responsive conjugates and PECs ensure miRNA stability against nucleases.•Nano PECs were easily obtained by electrostatic…”
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Nano polyelectrolyte complexes of carboxymethyl dextran and chitosan to improve chitosan-mediated delivery of miR-145
Published in Carbohydrate polymers (01-03-2017)“…•PEC stability and dissociation rate are crucial factors for gene delivery.•PEC preparation method affect its characteristics including size…”
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Development of a T Cell-targeted siRNA Delivery System Against HIV-1 Using Modified Superparamagnetic Iron Oxide Nanoparticles: An In Vitro Study
Published in Journal of pharmaceutical sciences (01-05-2022)“…In spite of the promising properties of small interfering RNAs (siRNAs) in the treatment of infectious diseases, safe and efficient siRNA delivery to target…”
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Reduced polydopamine coated graphene for delivery of Hset1 antisense as A photothermal and gene therapy of breast cancer
Published in Journal of drug delivery science and technology (01-07-2022)“…Breast cancer is the most prevalent type of cancer in women; hence, many researches have been focused on developing effective treatment protocols. In this…”
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Preparation and Investigation of Sustained Drug Delivery Systems Using an Injectable, Thermosensitive, In Situ Forming Hydrogel Composed of PLGA–PEG–PLGA
Published in AAPS PharmSciTech (01-06-2012)“…In situ gelling systems are very attractive for pharmaceutical applications due to their biodegradability and simple manufacturing processes. The synthesis and…”
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RETRACTED ARTICLE: Codelivery of HIF-1α siRNA and Dinaciclib by Carboxylated Graphene Oxide-Trimethyl Chitosan-Hyaluronate Nanoparticles Significantly Suppresses Cancer Cell Progression
Published in Pharmaceutical research (01-10-2020)“…Purpose Hypoxia-inducible factor (HIF) is one of the critical components of the tumor microenvironment that is involved in tumor development. HIF-1α…”
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Chitosan polyplex nanoparticle vector for miR-145 expression in MCF-7: Optimization by design of experiment
Published in International journal of biological macromolecules (01-11-2015)“…miR-145, a tumor suppressor micro RNA (miRNA), is down regulated in cancer and can be introduced as a therapeutic agent in various cancers including breast…”
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Preparation and investigation of smart hydrogels of thiolated dextran and miR-145
Published in Journal of controlled release (10-09-2015)Get full text
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