Search Results - "Tejera, Noemi"
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Significance of long chain polyunsaturated fatty acids in human health
Published in Clinical and translational medicine (27-07-2017)“…In the last decades, the development of new technologies applied to lipidomics has revitalized the analysis of lipid profile alterations and the understanding…”
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2
Autoxidative and Cyclooxygenase-2 Catalyzed Transformation of the Dietary Chemopreventive Agent Curcumin
Published in The Journal of biological chemistry (14-01-2011)“…The efficacy of the diphenol curcumin as a cancer chemopreventive agent is limited by its chemical and metabolic instability. Non-enzymatic degradation has…”
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3
The effect of dietary fish oil on weight gain and insulin sensitivity is dependent on APOE genotype in humanized targeted replacement mice
Published in The FASEB journal (01-03-2017)“…ABSTRACT We investigated the independent and interactive impact of the common APOE genotype and marine n‐3 polyunsaturated fatty acids (PUFAs) on the…”
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4
Differential effects of EPA versus DHA on postprandial vascular function and the plasma oxylipin profile in men
Published in Journal of lipid research (01-09-2016)“…Our objective was to investigate the impact of EPA versus DHA on arterial stiffness and reactivity and underlying mechanisms (with a focus on plasma oxylipins)…”
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The Influence of APOE Genotype, DHA, and Flavanol Intervention on Brain DHA and Lipidomics Profile in Aged Transgenic Mice
Published in Nutrients (23-04-2023)“…The apolipoprotein E4 ( ) genotype is predictive of Alzheimer's disease (AD). The brain is highly enriched with the omega-3 polyunsaturated fatty acid…”
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6
Genome-Scale Metabolic Model Driven Design of a Defined Medium for Campylobacter jejuni M1cam
Published in Frontiers in microbiology (19-06-2020)“…Campylobacter jejuni , the most frequent cause of food-borne bacterial gastroenteritis, is a fastidious organism when grown in the laboratory. Oxygen is…”
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Genome-Scale Metabolic Modelling Approach to Understand the Metabolism of the Opportunistic Human Pathogen Staphylococcus epidermidis RP62A
Published in Metabolites (02-02-2022)“…is a common commensal of collagen-rich regions of the body, such as the skin, but also represents a threat to patients with medical implants (joints and…”
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Transactivation of EGFR by LPS induces COX-2 expression in enterocytes
Published in PloS one (31-05-2012)“…Necrotizing enterocolitis (NEC) is the leading cause of gastrointestinal morbidity and mortality in preterm infants. NEC is characterized by an exaggerated…”
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COX-2-dependent and -independent biosynthesis of dihydroxy-arachidonic acids in activated human leukocytes
Published in Journal of lipid research (01-01-2012)“…Biosynthesis of 5,15-dihydroxyeicosatetraenoic acid (5,15-diHETE) in leukocytes involves consecutive oxygenation of arachidonic acid by 5-lipoxygenase (LOX)…”
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Substrate Utilisation and Energy Metabolism in Non-Growing Campylobacter jejuni M1cam
Published in Microorganisms (Basel) (05-07-2022)“…, the major cause of bacterial foodborne illness, is also a fastidious organism that requires strict growth requirements in the laboratory. Our aim was to…”
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Biosynthesis of hemiketal eicosanoids by cross-over of the 5-lipoxygenase and cyclooxygenase-2 pathways
Published in Proceedings of the National Academy of Sciences - PNAS (26-04-2011)“…The prostaglandin and leukotriene families of lipid mediators are formed via two distinct biosynthetic pathways that are initiated by the oxygénation of…”
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Identification and absolute configuration of dihydroxy-arachidonic acids formed by oxygenation of 5S-HETE by native and aspirin-acetylated COX-2
Published in Journal of lipid research (01-03-2010)“…Biosynthesis of the prostaglandin endoperoxide by the cyclooxygenase (COX) enzymes is accompanied by formation of a small amount of 11R-hydroxyeicosatetraenoic…”
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MetaboLights: open data repository for metabolomics
Published in Nucleic acids research (05-01-2024)“…Abstract MetaboLights is a global database for metabolomics studies including the raw experimental data and the associated metadata. The database is…”
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A comparative analysis of nutritional quality, amino acid profile, and nutritional supplementations in plant-based products and their animal-based counterparts in the UK
Published in Food chemistry (01-08-2024)“…Plant-based (PB) food products have surged in popularity over the past decade. Available PB products in the UK market were extracted from NielsenIQ Brandbank…”
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APOE genotype influences the gut microbiome structure and function in humans and mice: relevance for Alzheimer's disease pathophysiology
Published in The FASEB journal (01-07-2019)“…ABSTRACT Apolipoprotein E (APOE) genotype is the strongest prevalent genetic risk factor for Alzheimer's disease (AD). Numerous studies have provided insights…”
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APOE4 genotype exacerbates the impact of menopause on cognition and synaptic plasticity in APOE‐TR mice
Published in The FASEB journal (01-05-2021)“…The impact of sex and menopausal status in Alzheimer’s disease remains understudied despite increasing evidence of greater female risk, particularly in APOE4…”
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Altered SPMs and age‐associated decrease in brain DHA in APOE4 female mice
Published in The FASEB journal (01-09-2019)“…ABSTRACTAn apolipoprotein E (APOE) 4 genotype is the most important, common genetic determinant for Alzheimer disease (AD), and female APOE4 carriers present…”
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Pigmentation, carotenoids, lipid peroxides and lipid composition of skin of red porgy ( Pagrus pagrus) fed diets supplemented with different astaxanthin sources
Published in Aquaculture (28-09-2007)“…A feeding experiment was carried out to determine the efficiency of different commercial sources, chemical forms and levels, of dietary astaxanthin, to…”
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The Influence of IAPOE/I Genotype, DHA, and Flavanol Intervention on Brain DHA and Lipidomics Profile in Aged Transgenic Mice
Published in Nutrients (01-04-2023)“…The apolipoprotein E4 (APOE4) genotype is predictive of Alzheimer's disease (AD). The brain is highly enriched with the omega-3 polyunsaturated fatty acid…”
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20
n-3 Fatty acids combined with flavan-3-ols prevent steatosis and liver injury in a murine model of NAFLD
Published in Biochimica et biophysica acta. Molecular basis of disease (01-01-2018)“…Non-alcoholic fatty liver disease (NAFLD) affects 25% of adults and at present no licensed medication has been approved. Despite its complex patho-physiology,…”
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