Search Results - "Tejedor, Juan R"
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DNA methylation reprogramming of human cancer cells by expression of a plant 5-methylcytosine DNA glycosylase
Published in Epigenetics (01-01-2018)“…Patterns of DNA methylation, an important epigenetic modification involved in gene silencing and development, are disrupted in cancer cells. Understanding the…”
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Epigenetic downregulation of TET3 reduces genome‐wide 5hmC levels and promotes glioblastoma tumorigenesis
Published in International journal of cancer (15-01-2020)“…Loss of 5‐hydroxymethylcytosine (5hmC) has been associated with mutations of the ten–eleven translocation (TET) enzymes in several types of cancer. However,…”
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Enhanced Detection of Viral RNA Species Using FokI-Assisted Digestion of DNA Duplexes and DNA/RNA Hybrids
Published in Analytical chemistry (Washington) (10-05-2022)“…The accurate detection of nucleic acids from certain biological pathogens is critical for the diagnosis of human diseases. However, amplified detection of RNA…”
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A FokI-driven signal amplification platform for the simultaneous detection of multiple viral RNA pathogens
Published in Sensors & diagnostics (14-03-2024)“…Accurate signal quantification is a critical parameter for precise pathogen diagnosis. Furthermore, the development of novel diagnostic methods amenable for…”
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