Search Results - "Teixeira da Rosa, Nevton"

Upregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction in tafazzin-deficient cells by Liang, Zhuqing, Ralph-Epps, Tyler, Schmidtke, Michael W., Lazcano, Pablo, Denis, Simone W., Balážová, Mária, Teixeira da Rosa, Nevton, Chakkour, Mohamed, Hazime, Sanaa, Ren, Mindong, Schlame, Michael, Houtkooper, Riekelt H., Greenberg, Miriam L.

“…Barth syndrome (BTHS) is a rare disorder caused by mutations in the TAFAZZIN gene. Previous studies from both patients and model systems have established…”
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Author Correction: Upregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction in tafazzin-deficient cells by Liang, Zhuqing, Ralph-Epps, Tyler, Schmidtke, Michael W., Lazcano, Pablo, Denis, Simone W., Balážová, Mária, Teixeira da Rosa, Nevton, Chakkour, Mohamed, Hazime, Sanaa, Ren, Mindong, Schlame, Michael, Houtkooper, Riekelt H., Greenberg, Miriam L.

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The mitochondrial‐targeted reactive species scavenger JP4‐039 prevents sulfite‐induced alterations in antioxidant defenses, energy transfer, and cell death signaling in striatum of rats by Glänzel, Nícolas Manzke, Grings, Mateus, da Rosa‐Junior, Nevton Teixeira, Carvalho, Leila Maria Cereta, Mohsen, Al‐Walid, Wipf, Peter, Wajner, Moacir, Vockley, Jerry, Leipnitz, Guilhian

“…Sulfite oxidase (SO) deficiency is a disorder caused either by isolated deficiency of SO or by defects in the synthesis of its molybdenum cofactor. It is…”
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Bezafibrate Prevents Glycine-Induced Increase of Antioxidant Enzyme Activities in Rat Striatum by Parmeggiani, Belisa, Grings, Mateus, da Rosa-Junior, Nevton Teixeira, Britto, Renata, Wajner, Moacir, Leipnitz, Guilhian

“…Non-ketotic hyperglycinemia (NKH) is a severe neurological disorder caused by defects in glycine (GLY) catabolism and characterized by a high cerebrospinal…”
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TRF1 as a major contributor for telomeres' shortening in the context of obesity by Grun, Lucas Kich, Teixeira, Nevton da Rosa, Mengden, Lúcia von, de Bastiani, Marco Antônio, Parisi, Mariana Migliorini, Bortolin, Rafael, Lavandoski, Patrícia, Pierdoná, Vinícius, Alves, Letícia Biscaino, Moreira, José Cláudio Fonseca, Mottin, Cláudio Corá, Jones, Marcus Herbert, Klamt, Fábio, Padoin, Alexandre Vontobel, Guma, Fátima Costa Rodrigues, Barbé-Tuana, Florencia María

“…Obesity is a prevalent multifactorial chronic disorder characterized by metabolic dysregulation. Sustained pro-oxidative mediators trigger harmful consequences…”
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Antioxidant system disturbances and mitochondrial dysfunction induced by 3-methyglutaric acid in rat heart are prevented by bezafibrate by da Rosa-Junior, Nevton Teixeira, Parmeggiani, Belisa, Glänzel, Nícolas Manzke, de Moura Alvorcem, Leonardo, Brondani, Morgana, Britto, Renata, Grings, Mateus, Ortiz, Vanessa Duarte, Turck, Patrick, da Rosa Araujo, Alex Sander, Wajner, Moacir, Leipnitz, Guilhian

“…Barth syndrome (BTHS) and dilated cardiomyopathy with ataxia syndrome (DCMA) are biochemically characterized by high levels of 3-methylglutaric acid (MGA) in…”
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In vivo evidence that bezafibrate prevents oxidative stress and mitochondrial dysfunction caused by 3-methylglutaric acid in rat liver by da Rosa-Junior, Nevton Teixeira, Parmeggiani, Belisa, Glänzel, Nícolas Manzke, de Moura Alvorcem, Leonardo, Frusciante, Marina Rocha, Dutra Filho, Carlos Severo, Wajner, Moacir, Leipnitz, Guilhian

“…High urinary excretion and tissue accumulation of 3-methylglutaric acid (MGA) are observed in patients affected by 3-hydroxy-3-methylglutaric (HMGA) and…”
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Bezafibrate In Vivo Administration Prevents 3-Methylglutaric Acid-Induced Impairment of Redox Status, Mitochondrial Biogenesis, and Neural Injury in Brain of Developing Rats by da Rosa-Junior, Nevton Teixeira, Parmeggiani, Belisa, da Rosa, Mateus Struecker, Glänzel, Nícolas Manzke, de Moura Alvorcem, Leonardo, Wajner, Moacir, Leipnitz, Guilhian

“…3-Methylglutaric acid (MGA) is an organic acid that accumulates in 3-methylglutaconic (MGTA) and 3-hydroxy-3-methylglutaric (HMGA) acidurias. Patients affected…”
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3-Hydroxy-3-Methylglutaric Acid Impairs Redox and Energy Homeostasis, Mitochondrial Dynamics, and Endoplasmic Reticulum–Mitochondria Crosstalk in Rat Brain by da Rosa, Mateus Struecker, da Rosa-Junior, Nevton Teixeira, Parmeggiani, Belisa, Glänzel, Nícolas Manzke, de Moura Alvorcem, Leonardo, Ribeiro, Rafael Teixeira, Grings, Mateus, Wajner, Moacir, Leipnitz, Guilhian

“…3-Hydroxy-3-methylglutaryl-CoA lyase (HL) deficiency is a neurometabolic disorder characterized by predominant accumulation of 3-hydroxy-3-methylglutaric acid…”
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Evidence that thiol group modification and reactive oxygen species are involved in hydrogen sulfide-induced mitochondrial permeability transition pore opening in rat cerebellum by de Moura Alvorcem, Leonardo, Britto, Renata, Parmeggiani, Belisa, Glanzel, Nícolas Manzke, da Rosa-Junior, Nevton Teixeira, Cecatto, Cristiane, Bobermin, Larissa Daniele, Amaral, Alexandre Umpierrez, Wajner, Moacir, Leipnitz, Guilhian

“…We report here the effects of hydrogen sulfide (sulfide), that accumulates in ETHE1 deficiency, in rat cerebellum. Sulfide impaired electron transfer and…”
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