Percutaneous treatments of primary aneurysmal bone cysts: systematic review and meta-analysis

Purpose To systematically review the literature to determine recurrence rates of percutaneous treatments for primary aneurysmal bone cysts (ABC). Methods Search strategies were performed in the following databases: PubMed, SCIELO, LILACS and BVS, using terms in English, Spanish and Portuguese (PROSP...

Full description

Saved in:

Bibliographic Details
Published in:	European journal of orthopaedic surgery & traumatology Vol. 31; no. 7; pp. 1287 - 1295
Main Authors:	Cruz, Gabriel Schmitt, Cuevas-Suárez, Carlos Enrique, Saavedra, Juan Pablo Aitken, Giorgis, Rafael, Teixeira, Matheus Ricardo Kishimoto, Muniz, Francisco Wilker Mustafa Gomes
Format:	Journal Article
Language:	English
Published:	Paris Springer Paris 01-10-2021 Springer Nature B.V
Subjects:	Clinical trials Cysts Embolization General Review Medicine Medicine & Public Health Meta-analysis Sclerotherapy Surgical Orthopedics Traumatic Surgery Bone cysts Recurrence Embolization Sclerotherapy
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Purpose To systematically review the literature to determine recurrence rates of percutaneous treatments for primary aneurysmal bone cysts (ABC). Methods Search strategies were performed in the following databases: PubMed, SCIELO, LILACS and BVS, using terms in English, Spanish and Portuguese (PROSPERO Registration Number: CRD42020170340). Longitudinal studies, either observational or clinical trials, with at least five patients and with a mean of 18 months of follow-up were included. Studies had to use any type of percutaneous treatments and report the recurrence rates of primary ABC treatment. Studies selection, data extraction and risk of bias assessment were performed independently by two researchers. A global meta-analysis was carried out to assess the proportion of recurrence. Studies were categorized into two subgroups: selective arterial embolization and sclerotherapy. Results Thirteen studies were included in the present study. The average success rate of percutaneous treatments for ABC was 91.11%, with a total of 37 lesions recurrences in the 416 patients. The sex ratio was 1:1. The subgroup of sclerotherapies presented a lower proportion of recurrence. The proportion of recurrence in the subgroup of selective arterial embolization was 19% (95%IC 12.11–27.54) and that of sclerotherapies was 6% (95%IC 3.65–9.19). Conclusions Both percutaneous treatments for ABC are effective, showing a lower rate of recurrence. Sclerotherapy treatments seem to be promising, but further clinical trials must be conducted with a longer follow-up.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 ObjectType-Review-4 content type line 23 ObjectType-Undefined-3
ISSN:	1633-8065 1432-1068
DOI:	10.1007/s00590-021-02893-6