Search Results - "Teixeira, Jose M"

ARID1A and PI3-kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion by Wilson, Mike R., Reske, Jake J., Holladay, Jeanne, Wilber, Genna E., Rhodes, Mary, Koeman, Julie, Adams, Marie, Johnson, Ben, Su, Ren-Wei, Joshi, Niraj R., Patterson, Amanda L., Shen, Hui, Leach, Richard E., Teixeira, Jose M., Fazleabas, Asgerally T., Chandler, Ronald L.

“…ARID1A and PI3-Kinase (PI3K) pathway alterations are common in neoplasms originating from the uterine endometrium. Here we show that monoallelic loss of ARID1A…”
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Putative human myometrial and fibroid stem-like cells have mesenchymal stem cell and endometrial stromal cell properties by Patterson, Amanda L, George, Jitu W, Chatterjee, Anindita, Carpenter, Tyler J, Wolfrum, Emily, Chesla, David W, Teixeira, Jose M

“…Abstract STUDY QUESTION Can endometrial stromal stem/progenitor cell markers, SUSD2 and CD146/CD140b, enrich for human myometrial and fibroid stem/progenitor…”
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PIK3CA mutation in endometriotic epithelial cells promotes viperin-dependent inflammatory response to insulin by Wilson, Mike R, Harkins, Shannon, Reske, Jake J, Siwicki, Rebecca A, Adams, Marie, Bae-Jump, Victoria L, Teixeira, Jose M, Chandler, Ronald L

“…Endometrial epithelia are known to harbor cancer driver mutations in the absence of any pathologies, including mutations in PIK3CA. Insulin plays an important…”
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Transcriptome Analyses of Myometrium from Fibroid Patients Reveals Phenotypic Differences Compared to Non-Diseased Myometrium by Paul, Emmanuel N, Burns, Gregory W, Carpenter, Tyler J, Grey, Joshua A, Fazleabas, Asgerally T, Teixeira, Jose M

“…Uterine fibroid tissues are often compared to their matched myometrium in an effort to understand their pathophysiology, but it is not clear whether the…”
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Obesity alters the mouse endometrial transcriptome in a cell context-dependent manner by Wilson, Mike R, Skalski, Hilary, Reske, Jake J, Wegener, Marc, Adams, Marie, Hostetter, Galen, Hoffmann, Hanne M, Bernard, Jamie J, Bae-Jump, Victoria L, Teixeira, Jose M, Chandler, Ronald L

“…Obesity impacts fertility and is positively correlated with endometrial hyperplasia and endometrial cancer occurrence. Endometrial epithelia often harbor…”
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Stromal liver kinase B1 [STK11] signaling loss induces oviductal adenomas and endometrial cancer by activating mammalian Target of Rapamycin Complex 1 by Tanwar, Pradeep S, Kaneko-Tarui, Tomoko, Zhang, Lihua, Tanaka, Yoshihiro, Crum, Christopher P, Teixeira, Jose M

“…Germline mutations of the Liver Kinase b1 (LKB1/STK11) tumor suppressor gene have been linked to Peutz-Jeghers Syndrome (PJS), an autosomal-dominant,…”
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Constitutive Activation of Beta-Catenin in Uterine Stroma and Smooth Muscle Leads to the Development of Mesenchymal Tumors in Mice by Tanwar, Pradeep S, Lee, Ho-Joon, Zhang, LiHua, Zukerberg, Lawrence R, Taketo, Makoto M, Rueda, Bo R, Teixeira, Jose M

“…Leiomyomas and other mesenchymally derived tumors are the most common neoplasms of the female reproductive tract. Presently, very little is known about the…”
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Stromal Deletion of the APC Tumor Suppressor in Mice Triggers Development of Endometrial Cancer by TANWAR, Pradeep S, LIHUA ZHANG, ROBERTS, Drucilla J, TEIXEIRA, Jose M

“…The contribution of the stromal microenvironment to the progression of endometrial cancer has not been well explored. We have conditionally expressed a mutant…”
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Cysteine-rich intestinal protein 1 is a novel surface marker for human myometrial stem/progenitor cells by Paul, Emmanuel N., Carpenter, Tyler J., Fitch, Sarah, Sheridan, Rachael, Lau, Kin H., Arora, Ripla, Teixeira, Jose M.

“…Myometrial stem/progenitor cells (MyoSPCs) have been proposed as the cells of origin for uterine fibroids, but the identity of the MyoSPC has not been well…”
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Ni-Co Alloy and Multisegmented Ni/Co Nanowire Arrays Modulated in Composition: Structural Characterization and Magnetic Properties by Méndez, Miguel, González, Silvia, Vega, Víctor, Teixeira, Jose, Hernando, Blanca, Luna, Carlos, Prida, Víctor

“…Design of novel multisegmented magnetic nanowires can pave the way for the next generation of data storage media and logical devices, magnonic crystals, or in…”
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Deletion of Tuberous Sclerosis 1 in Somatic Cells of the Murine Reproductive Tract Causes Female Infertility by Tanaka, Yoshihiro, Park, Joo Hyun, Tanwar, Pradeep S, Kaneko-Tarui, Tomoko, Mittal, Shilpi, Lee, Ho-Joon, Teixeira, Jose M

“…Tumors develop with dysregulated activation of mammalian target of rapamycin (mTOR), the kinase activity of which is kept in an inactive state by a tumor…”
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Transcriptome and DNA methylome analyses reveal underlying mechanisms for the racial disparity in uterine fibroids by Paul, Emmanuel N, Grey, Joshua A, Carpenter, Tyler J, Madaj, Zachary B, Lau, Kin H, Givan, Scott A, Burns, Gregory W, Chandler, Ronald L, Wegienka, Ganesa R, Shen, Hui, Teixeira, Jose M

“…Uterine fibroids (leiomyomas) affect Black women disproportionately compared with women of other races and ethnicities in terms of prevalence, incidence, and…”
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A model for identifying owner's needs in the building life cycle by Alshubbak, Ali, Pellicer, Eugenio, Catalá, Joaquín, Teixeira, José M. C.

“…Building life cycle is a process which covers not only the construction phase but also the feasibility, the de- sign and the operation phases. Identifying the…”
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Endometrial stromal beta-catenin is required for steroid-dependent mesenchymal-epithelial cross talk and decidualization by Zhang, Ling, Patterson, Amanda L, Zhang, Lihua, Teixeira, Jose M, Pru, James K

“…Beta-catenin is part of a protein complex associated with adherens junctions. When allowed to accumulate to sufficient levels in its dephosphorylated form,…”
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Mammalian target of rapamycin is a therapeutic target for murine ovarian endometrioid adenocarcinomas with dysregulated Wnt/β-catenin and PTEN by Tanwar, Pradeep S, Zhang, LiHua, Kaneko-Tarui, Tomoko, Curley, Michael D, Taketo, Makoto M, Rani, Poonam, Roberts, Drucilla J, Teixeira, Jose M

“…Despite the fact that epithelial ovarian cancers are the leading cause of death from gynecological cancer, very little is known about the pathophysiology of…”
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Induction of WNT inhibitory factor 1 expression by Müllerian inhibiting substance/antiMullerian hormone in the Müllerian duct mesenchyme is linked to Müllerian duct regression by Park, Joo Hyun, Tanaka, Yoshihiro, Arango, Nelson A., Zhang, Lihua, Benedict, L. Andrew, Roh, Mi In, Donahoe, Patricia K., Teixeira, Jose M.

“…A key event during mammalian sexual development is regression of the Müllerian ducts (MDs) in the bipotential urogenital ridges (UGRs) of fetal males, which is…”
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Two new begomoviruses that infect non-cultivated malvaceae in Brazil by Passos, Laíse S., Teixeira, José Wilgney M., Teixeira, Kelvin Josemar M. L., Xavier, César Augusto D., Zerbini, F. Murilo, Araújo, Ademir Sergio F., Beserra, José Evando A.

“…A high diversity of begomoviruses that infect non-cultivated plants has been noted in Brazil. Here, we report the complete sequences of two new species of…”
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Epidemiological and genetic clues for molecular mechanisms involved in uterine leiomyoma development and growth by Commandeur, Arno E, Styer, Aaron K, Teixeira, Jose M

“…Uterine leiomyomas (fibroids) are highly prevalent benign smooth muscle tumors of the uterus. In the USA, the lifetime risk for women developing uterine…”
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Focal Müllerian duct retention in male mice with constitutively activated β-catenin expression in the Müllerian duct mesenchyme by Tanwar, Pradeep S., Zhang, LiHua, Tanaka, Yoshihiro, Taketo, Makoto M., Donahoe, Patricia K., Teixeira, Jose M.

“…Müllerian-inhibiting substance (MIS), which is produced by fetal Sertoli cells shortly after commitment of the bipotential gonads to testicular…”
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Pathogenic Anti-Müllerian Hormone Variants in Polycystic Ovary Syndrome by Gorsic, Lidija K, Kosova, Gulum, Werstein, Brian, Sisk, Ryan, Legro, Richard S, Hayes, M Geoffrey, Teixeira, Jose M, Dunaif, Andrea, Urbanek, Margrit

“…Abstract Context Polycystic ovary syndrome (PCOS), a common endocrine condition, is the leading cause of anovulatory infertility. Objective Given that common…”
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