Search Results - "Teixeira, Fabio G"

Impact of the Secretome of Human Mesenchymal Stem Cells on Brain Structure and Animal behavior in a Rat Model of Parkinson’s Disease by Teixeira, Fábio Gabriel Rodrigues, Carvalho, Miguel M., Panchalingam, K. M., Rodrigues, Ana João, Pinheiro, Bárbara Filipa Mendes, Anjo, Sandra, Manadas, Bruno, Behie, Leo A., Sousa, Nuno, Salgado, A. J.

“…Research in the last decade strongly suggests that mesenchymal stem cell (MSC)-mediated therapeutic benefits are mainly due to their secretome, which has been…”
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Unveiling the Differences of Secretome of Human Bone Marrow Mesenchymal Stem Cells, Adipose Tissue-Derived Stem Cells, and Human Umbilical Cord Perivascular Cells: A Proteomic Analysis by Pires, Ana O, Mendes-Pinheiro, Barbara, Teixeira, Fábio G, Anjo, Sandra I, Ribeiro-Samy, Silvina, Gomes, Eduardo D, Serra, Sofia C, Silva, Nuno A, Manadas, Bruno, Sousa, Nuno, Salgado, Antonio J

“…The use of human mesenchymal stem cells (hMSCs) has emerged as a possible therapeutic strategy for CNS-related conditions. Research in the last decade strongly…”
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Co-Transplantation of Adipose Tissue-Derived Stromal Cells and Olfactory Ensheathing Cells for Spinal Cord Injury Repair by Gomes, Eduardo D., Mendes, Sofia Silva, Silva, Rita Catarina Assunção Ribeiro, Teixeira, Fábio Gabriel Rodrigues, Pires, Ana O., Anjo, Sandra I., Manadas, Bruno, Leite-Almeida, Hugo, Gimble, Jeffrey M., Sousa, Nuno, Lepore, Angelo C., Silva, Nuno André Martins, Salgado, A. J.

“…Patients suffering from spinal cord injury (SCI) still have a dismal prognosis. Despite all the efforts developed in this area, currently there are no…”
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Impact of aging on the 6-OHDA-induced rat model of Parkinson’s disease by Barata-Antunes, Sandra, Teixeira, Fábio G., Mendes-Pinheiro, Bárbara, Domingues, Ana V., Vilaça-Faria, Helena, Marote, Ana, Silva, Deolinda, Sousa, R. A., Salgado, A. J.

“…Parkinson’s disease (PD) is the second most common age-related neurodegenerative disorder. The neurodegeneration leading to incapacitating motor abnormalities…”
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Modulation of the mesenchymal stem cell secretome using computer-controlled bioreactors: impact on neuronal cell proliferation, survival and differentiation by Teixeira, Fábio Gabriel Rodrigues, Panchalingam, Krishna M., Silva, Rita Catarina Assunção Ribeiro, Serra, Sofia Cravino, Pinheiro, Bárbara Filipa Mendes, Patrício, P., Jung, Sunghoon, Anjo, Sandra I., Manadas, Bruno, Pinto, Luísa, Sousa, Nuno, Behie, Leo A., Salgado, A. J.

“…In recent years it has been shown that the therapeutic benefits of human mesenchymal stem/ stromal cells (hMSCs) in the Central Nervous System (CNS) are mainly…”
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Glial-restricted precursors stimulate endogenous cytogenesis and effectively recover emotional deficits in a model of cytogenesis ablation by Martins-Macedo, Joana, Araújo, Bruna, Anjo, Sandra I., Silveira-Rosa, Tiago, Patrício, Patrícia, Alves, Nuno Dinis, Silva, Joana M., Teixeira, Fábio G., Manadas, Bruno, Rodrigues, Ana J., Lepore, Angelo C., Salgado, António J., Gomes, Eduardo D., Pinto, Luísa

“…Adult cytogenesis, the continuous generation of newly-born neurons (neurogenesis) and glial cells (gliogenesis) throughout life, is highly impaired in several…”
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Bone marrow mesenchymal stem cells' secretome exerts neuroprotective effects in a Parkinson's disease rat model by Pinheiro, Bárbara Filipa Mendes, Anjo, Sandra I., Manadas, Bruno, da Silva, Jorge D., Marote, Ana Maria Franco Aveiro, Behie, Leo A., Teixeira, Fábio G., Salgado, A. J.

“…Parkinson's disease (PD) is characterized by a selective loss of dopamine (DA) neurons in the human midbrain causing motor dysfunctions. The exact mechanism…”
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Mesenchymal stem cells secretome-induced axonal outgrowth is mediated by BDNF by Martins, Luís F., Costa, Rui O., Pedro, Joana R., Aguiar, Paulo, Serra, Sofia Cravino, Teixeira, Fábio Gabriel Rodrigues, Sousa, Nuno, Salgado, A. J., Almeida, Ramiro D.

“…Mesenchymal stem cells (MSCs) have been used for cell-based therapies in regenerative medicine, with increasing importance in central and peripheral nervous…”
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Mesenchymal stem cells in the umbilical cord: phenotypic characterization, secretome and applications in central nervous system regenerative medicine by Carvalho, Miguel M, Teixeira, Fábio G, Reis, Rui L, Sousa, Nuno, Salgado, António J

“…Mesenchymal Stem Cells (MSCs), have been defined and characterized by: 1) their ability to adhere to plastic culture flasks; 2) the positive expression of…”
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Influence of passage number on the impact of the secretome of adipose tissue stem cells on neural survival, neurodifferentiation and axonal growth by Serra, Sofia C., Costa, João C., Assunção-Silva, Rita C., Teixeira, Fábio G., Silva, Nuno A., Anjo, Sandro I., Manadas, Bruno, Gimble, Jeffrey M., Behie, Leo A., Salgado, António J.

“…Mesenchymal stem cells (MSCs), and within them adipose tissue derived stem cells (ASCs), have been shown to have therapeutic effects on central nervous system…”
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From the Gut to the Brain: Is Microbiota a New Paradigm in Parkinson's Disease Treatment? by Vilela, Cristiana, Araújo, Bruna, Soares-Guedes, Carla, Caridade-Silva, Rita, Martins-Macedo, Joana, Teixeira, Catarina, Gomes, Eduardo D, Prudêncio, Cristina, Vieira, Mónica, Teixeira, Fábio G

“…Parkinson's disease (PD) is recognized as the second most prevalent primary chronic neurodegenerative disorder of the central nervous system. Clinically, PD is…”
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Bioengineered cell culture systems of central nervous system injury and disease by Teixeira, Fábio G., Vasconcelos, Natália L., Gomes, Eduardo D., Marques, Fernanda, Sousa, João C., Sousa, Nuno, Silva, Nuno A., Assunção-Silva, Rita, Lima, Rui, Salgado, António J.

“…•3D cell culture models are needed in as current 2D models do not recapitulate the CNS niche.•Combinatory strategies using cells, hydrogels and microfluidics…”
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Mesenchymal stem cells secretome: a new paradigm for central nervous system regeneration? by Teixeira, Fábio G, Carvalho, Miguel M, Sousa, Nuno, Salgado, António J

“…The low regeneration potential of the central nervous system (CNS) represents a challenge for the development of new therapeutic strategies. Mesenchymal stem…”
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Mesenchymal stem cells secretome: current trends and future challenges by Teixeira, Fábio, Salgado, António

“…[...]over the last decade, the use of stem cells has remarkably been proposed as a regenerative tool, and within it, MSCs have emerged as a promising…”
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Mesenchymal Stem Cells-derived Exosomes: A New Possible Therapeutic Strategy for Parkinson's Disease? by Vilaça-Faria, Helena, Salgado, António J, Teixeira, Fábio G

“…Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder worldwide. Clinically, it is characterized by severe motor complications…”
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MSCs-Derived Exosomes: Cell-Secreted Nanovesicles with Regenerative Potential by Marote, Ana, Teixeira, Fábio G, Mendes-Pinheiro, Bárbara, Salgado, António J

“…Exosomes are membrane-enclosed nanovesicles (30-150 nm) that shuttle active cargoes between different cells. These tiny extracellular vesicles have been…”
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Neuroinflammation and Parkinson’s disease—from neurodegeneration to therapeutic opportunities by Araújo, Bruna, Caridade-Silva, Rita, Soares-Guedes, Carla, Martins-Macedo, Joana, Gomes, Eduardo D., Monteiro, Susana, Teixeira, Fábio G.

“…Parkinson’s disease (PD) is the second most prevalent neurodegenerative disorder world wide. Clinically, it is characterized by a progressive degeneration of…”
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Secretome of Mesenchymal Progenitors from the Umbilical Cord Acts as Modulator of Neural/Glial Proliferation and Differentiation by Teixeira, Fábio Gabriel Rodrigues, Carvalho, Miguel Moreira, Carvalho, Andreia Alexandra Neves, Panchalingam, Krishna M., Behie, Leo A., Pinto, Luísa, Sousa, Nuno, Salgado, A. J.

“…It was recently shown that the conditioned media (CM) of Human Umbilical Cord Perivascular Cells (HUCPVCs), a mesenchymal progenitor population residing within…”
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Glial cells in Parkinson´s disease: protective or deleterious? by Domingues, Ana V., Pereira, Inês M., Vilaça-Faria, Helena, Salgado, António J., Rodrigues, Ana J., Teixeira, Fábio G.

“…Glial cells have been identified more than 100 years ago, and are known to play a key role in the central nervous system (CNS) function. A recent piece of…”
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Do hypoxia/normoxia culturing conditions change the neuroregulatory profile of Wharton Jelly mesenchymal stem cell secretome? by Teixeira, Fábio G, Panchalingam, Krishna M, Anjo, Sandra Isabel, Manadas, Bruno, Pereira, Ricardo, Sousa, Nuno, Salgado, António J, Behie, Leo A

“…The use of human umbilical cord Wharton Jelly-derived mesenchymal stem cells (hWJ-MSCs) has been considered a new potential source for future safe applications…”
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