Search Results - "Teipel, Stefan"

Spatial patterns of atrophy, hypometabolism, and amyloid deposition in Alzheimer's disease correspond to dissociable functional brain networks by Grothe, Michel J., Teipel, Stefan J.

“…Recent neuroimaging studies of Alzheimer's disease (AD) have emphasized topographical similarities between AD‐related brain changes and a prominent cortical…”
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Atrophy of the Cholinergic Basal Forebrain Over the Adult Age Range and in Early Stages of Alzheimer's Disease by Grothe, Michel, Heinsen, Helmut, Teipel, Stefan J

“…Background The basal forebrain cholinergic system (BFCS) is known to undergo moderate neurodegenerative changes during normal aging as well as severe atrophy…”
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Multimodal analysis of functional and structural disconnection in Alzheimer's disease using multiple kernel SVM by Dyrba, Martin, Grothe, Michel, Kirste, Thomas, Teipel, Stefan J.

“…Alzheimer's disease (AD) patients exhibit alterations in the functional connectivity between spatially segregated brain regions which may be related to both…”
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Longitudinal validity of PET‐based staging of regional amyloid deposition by Jelistratova, Irina, Teipel, Stefan J., Grothe, Michel J.

“…Positron emission tomography (PET)‐based staging of regional amyloid deposition has recently emerged as a promising tool for sensitive detection and…”
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In vivo cholinergic basal forebrain atrophy predicts cognitive decline in de novo Parkinson's disease by Ray, Nicola J, Bradburn, Steven, Murgatroyd, Christopher, Toseeb, Umar, Mir, Pablo, Kountouriotis, George K, Teipel, Stefan J, Grothe, Michel J

“…See Gratwicke and Foltynie (doi:10.1093/brain/awx333) for a scientific commentary on this article. Cognitive impairments in Parkinson's disease show variable…”
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Molecular properties underlying regional vulnerability to Alzheimer's disease pathology by Grothe, Michel J, Sepulcre, Jorge, Gonzalez-Escamilla, Gabriel, Jelistratova, Irina, Schöll, Michael, Hansson, Oskar, Teipel, Stefan J

“…See Lowe et al. (doi:10.1093/brain/awy226) for a scientific commentary on this article. Alzheimer's disease targets discrete neural systems, but the mechanisms…”
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Longitudinal measures of cholinergic forebrain atrophy in the transition from healthy aging to Alzheimer's disease by Grothe, Michel, Heinsen, Helmut, Teipel, Stefan

“…Abstract Recent evidence from cross-sectional in vivo imaging studies suggests that atrophy of the cholinergic basal forebrain (BF) in Alzheimer's disease (AD)…”
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MRI-based basal forebrain atrophy and volumetric signatures associated with limbic TDP-43 compared to Alzheimer's disease pathology by Teipel, Stefan, Grothe, Michel J.

“…It is not clear to which degree limbic TDP-43 pathology associates with a cholinergic deficit in the absence of Alzheimer's disease (AD) pathology. Replicate…”
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Cognitive Correlates of Basal Forebrain Atrophy and Associated Cortical Hypometabolism in Mild Cognitive Impairment by Grothe, Michel J, Heinsen, Helmut, Amaro, Jr, Edson, Grinberg, Lea T, Teipel, Stefan J

“…Degeneration of basal forebrain (BF) cholinergic nuclei is associated with cognitive decline, and this effect is believed to be mediated by neuronal…”
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Relationship between Basal Forebrain Resting-State Functional Connectivity and Brain Amyloid-β Deposition in Cognitively Intact Older Adults with Subjective Memory Complaints by Chiesa, Patrizia A, Cavedo, Enrica, Grothe, Michel J, Houot, Marion, Teipel, Stefan J, Potier, Marie-Claude, Habert, Marie-Odile, Lista, Simone, Dubois, Bruno, Hampel, Harald

“…Purpose To evaluate the association between the global fibrillary amyloid-β pathology and the basal forebrain connectivity at rest in cognitively intact older…”
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Relevance of Magnetic Resonance Imaging for Early Detection and Diagnosis of Alzheimer Disease by Teipel, Stefan J., MD, Grothe, Michel, PhD, Lista, Simone, PhD, Toschi, Nicola, PhD, Garaci, Francesco G., PhD, Hampel, Harald, MD

“…Magnetic resonance imaging (MRI)-based indicators of regional and global brain atrophy and more advanced measures of cortical functional and structural…”
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Atrophy of the cholinergic basal forebrain in dementia with Lewy bodies and Alzheimer’s disease dementia by Grothe, Michel J., Schuster, Christina, Bauer, Florian, Heinsen, Helmut, Prudlo, Johannes, Teipel, Stefan J.

“…Similar to Alzheimer’s disease (AD), dementia with Lewy bodies (DLB) is characterized by a profound degeneration of cortically-projecting cholinergic neurons…”
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“A brutal disadvantage for my wife [living with dementia] That has set us back years”: Results of a quantitative survey of caring relatives of people living with dementia during the Covid‐19 pandemic in Germany by Kowe, Antonia, Teipel, Stefan J

“…Background The Covid‐19 pandemic poses a major challenge to the entire population. People living with dementia and their caring relatives, mostly older people,…”
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“For whom the watch tolls”: Usability and feasibility of a smartwatch‐based intervention for people with dementia by Köhler, Stefanie, Goerss, Doreen, Teipel, Stefan J.

“…Background Zero‐effort technologies (ZET) are promising for supporting people with cognitive impairment. One needs to consider the user’s cognitive abilities,…”
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Public involvement to disseminate scientific findings in dementia care research: A quantitative survey on informal caregivers of people living with dementia by Kowe, Antonia, Lüthje, Corinna, Teipel, Stefan J

“…Background People living with dementia and their caring relatives can be involved in all phases of research, including the dissemination of research results…”
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Longitudinal trajectories of cognitive reserve in hypometabolic subtypes of Alzheimer's disease by Levin, Fedor, Grothe, Michel J, Dyrba, Martin, Franzmeier, Nicolai, Teipel, Stefan J

“…Previous studies have demonstrated resilience to AD-related neuropathology in a form of cognitive reserve (CR). In this study we investigated a relationship…”
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The effects of 7-week cognitive training in patients with vascular cognitive impairment, no dementia (the Cog-VACCINE study): A randomized controlled trial by Tang, Yi, Xing, Yi, Zhu, Zude, He, Yong, Li, Fang, Yang, Jianwei, Liu, Qing, Li, Fangyu, Teipel, Stefan J., Zhao, Guoguang, Jia, Jianping

“…Evidence for the efficacy of cognitive training in patients with subcortical vascular cognitive impairment no dementia is still lacking. A randomized, active…”
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Antemortem basal forebrain atrophy in pure limbic TAR DNA‐binding protein 43 pathology compared with pure Alzheimer pathology by Teipel, Stefan J., Grothe, Michel J.

“…Background and purpose Currently, the extent of cholinergic basal forebrain atrophy in relatively pure limbic TAR DNA‐binding protein 43 (TDP‐43) pathology…”
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Resting-state posterior alpha rhythms are abnormal in subjective memory complaint seniors with preclinical Alzheimer's neuropathology and high education level: the INSIGHT-preAD study by Babiloni, Claudio, Lopez, Susanna, Del Percio, Claudio, Noce, Giuseppe, Pascarelli, Maria Teresa, Lizio, Roberta, Teipel, Stefan J., González-Escamilla, Gabriel, Bakardjian, Hovagim, George, Nathalie, Cavedo, Enrica, Lista, Simone, Chiesa, Patrizia Andrea, Vergallo, Andrea, Lemercier, Pablo, Spinelli, Giuseppe, Grothe, Michel J., Potier, Marie-Claude, Stocchi, Fabrizio, Ferri, Raffaele, Habert, Marie-Odile, Fraga, Francisco J., Dubois, Bruno, Hampel, Harald

“…Cognitive reserve is present in Alzheimer's disease (AD) seniors with high education attainment making them clinically resilient to extended brain…”
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Neuropathologic features associated with basal forebrain atrophy in Alzheimer disease by Teipel, Stefan J., Fritz, H.-Christian, Grothe, Michel J.

“…To study the neuropathologic correlates of cholinergic basal forebrain (BF) atrophy as determined using antemortem MRI in the Alzheimer disease (AD) spectrum…”
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