Search Results - "Teipel, J."

Spatial patterns of atrophy, hypometabolism, and amyloid deposition in Alzheimer's disease correspond to dissociable functional brain networks by Grothe, Michel J., Teipel, Stefan J.

“…Recent neuroimaging studies of Alzheimer's disease (AD) have emphasized topographical similarities between AD‐related brain changes and a prominent cortical…”
Get full text

Atrophy of the Cholinergic Basal Forebrain Over the Adult Age Range and in Early Stages of Alzheimer's Disease by Grothe, Michel, Heinsen, Helmut, Teipel, Stefan J

“…Background The basal forebrain cholinergic system (BFCS) is known to undergo moderate neurodegenerative changes during normal aging as well as severe atrophy…”
Get full text

Multimodal analysis of functional and structural disconnection in Alzheimer's disease using multiple kernel SVM by Dyrba, Martin, Grothe, Michel, Kirste, Thomas, Teipel, Stefan J.

“…Alzheimer's disease (AD) patients exhibit alterations in the functional connectivity between spatially segregated brain regions which may be related to both…”
Get full text

In vivo cholinergic basal forebrain atrophy predicts cognitive decline in de novo Parkinson's disease by Ray, Nicola J, Bradburn, Steven, Murgatroyd, Christopher, Toseeb, Umar, Mir, Pablo, Kountouriotis, George K, Teipel, Stefan J, Grothe, Michel J

“…See Gratwicke and Foltynie (doi:10.1093/brain/awx333) for a scientific commentary on this article. Cognitive impairments in Parkinson's disease show variable…”
Get full text

Cognitive Correlates of Basal Forebrain Atrophy and Associated Cortical Hypometabolism in Mild Cognitive Impairment by Grothe, Michel J, Heinsen, Helmut, Amaro, Jr, Edson, Grinberg, Lea T, Teipel, Stefan J

“…Degeneration of basal forebrain (BF) cholinergic nuclei is associated with cognitive decline, and this effect is believed to be mediated by neuronal…”
Get full text

Relevance of Magnetic Resonance Imaging for Early Detection and Diagnosis of Alzheimer Disease by Teipel, Stefan J., MD, Grothe, Michel, PhD, Lista, Simone, PhD, Toschi, Nicola, PhD, Garaci, Francesco G., PhD, Hampel, Harald, MD

“…Magnetic resonance imaging (MRI)-based indicators of regional and global brain atrophy and more advanced measures of cortical functional and structural…”
Get full text

Data-driven FDG-PET subtypes of Alzheimer's disease-related neurodegeneration by Levin, Fedor, Ferreira, Daniel, Lange, Catharina, Dyrba, Martin, Westman, Eric, Buchert, Ralph, Teipel, Stefan J, Grothe, Michel J

“…Previous research has described distinct subtypes of Alzheimer's disease (AD) based on the differences in regional patterns of brain atrophy on MRI. We…”
Get full text

Automated detection of brain atrophy patterns based on MRI for the prediction of Alzheimer's disease by Plant, Claudia, Teipel, Stefan J., Oswald, Annahita, Böhm, Christian, Meindl, Thomas, Mourao-Miranda, Janaina, Bokde, Arun W., Hampel, Harald, Ewers, Michael

“…Subjects with mild cognitive impairment (MCI) have an increased risk to develop Alzheimer's disease (AD). Voxel-based MRI studies have demonstrated that widely…”
Get full text

Alzheimer's disease biomarker-guided diagnostic workflow using the added value of six combined cerebrospinal fluid candidates: Aβ1–42, total-tau, phosphorylated-tau, NFL, neurogranin, and YKL-40 by Hampel, Harald, Toschi, Nicola, Baldacci, Filippo, Zetterberg, Henrik, Blennow, Kaj, Kilimann, Ingo, Teipel, Stefan J., Cavedo, Enrica, Melo dos Santos, Antonio, Epelbaum, Stéphane, Lamari, Foudil, Genthon, Remy, Dubois, Bruno, Floris, Roberto, Garaci, Francesco, Lista, Simone

“…The diagnostic and classificatory performances of all combinations of three core (amyloid β peptide [i.e., Aβ1–42], total tau [t-tau], and phosphorylated tau)…”
Get full text

Basal forebrain atrophy and cortical amyloid deposition in nondemented elderly subjects by Grothe, Michel J, Ewers, Michael, Krause, Bernd, Heinsen, Helmut, Teipel, Stefan J

“…Abstract Background Both neurodegeneration of the cholinergic basal forebrain (BF) and deposition of β-amyloid are early events in the course of Alzheimer's…”
Get full text

Alkylphenolethoxylate in Antigen‐Schnelltests by Karlsruhe, Kosmetik‐Team, Teipel, J.

Get full text

Focal Decline of Cortical Thickness in Alzheimer's Disease Identified by Computational Neuroanatomy by Lerch, Jason P., Pruessner, Jens C., Zijdenbos, Alex, Hampel, Harald, Teipel, Stefan J., Evans, Alan C.

“…Alzheimer's disease (AD) is characterized by a heterogeneous distribution of pathological changes throughout the brain. Magnetic resonance imaging can be used…”
Get full text

Locus coeruleus MRI contrast is reduced in Alzheimer's disease dementia and correlates with CSF Aβ levels by Betts, Matthew J., Cardenas-Blanco, Arturo, Kanowski, Martin, Spottke, Annika, Teipel, Stefan J., Kilimann, Ingo, Jessen, Frank, Düzel, Emrah

“…This study aimed to assess how interindividual differences in locus coeruleus (LC) magnetic resonance imaging (MRI) contrast relate to cerebrospinal fluid…”
Get full text

The relative importance of imaging markers for the prediction of Alzheimer's disease dementia in mild cognitive impairment - Beyond classical regression by Teipel, Stefan J, Kurth, Jens, Krause, Bernd, Grothe, Michel J

“…Selecting a set of relevant markers to predict conversion from mild cognitive impairment (MCI) to Alzheimer's disease (AD) has become a challenging task given…”
Get full text

Which features of subjective cognitive decline are related to amyloid pathology? Findings from the DELCODE study by Miebach, Lisa, Wolfsgruber, Steffen, Polcher, Alexandra, Peters, Oliver, Menne, Felix, Luther, Katja, Incesoy, Enise, Priller, Josef, Spruth, Eike, Altenstein, Slawek, Buerger, Katharina, Catak, Cihan, Janowitz, Daniel, Perneczky, Robert, Utecht, Julia, Laske, Christoph, Buchmann, Martina, Schneider, Anja, Fliessbach, Klaus, Kalbhen, Pascal, Heneka, Michael T, Brosseron, Frederic, Spottke, Annika, Roy, Nina, Teipel, Stefan J, Kilimann, Ingo, Wiltfang, Jens, Bartels, Claudia, Düzel, Emrah, Dobisch, Laura, Metzger, Coraline, Meiberth, Dix, Ramirez, Alfredo, Jessen, Frank, Wagner, Michael

“…Subjective cognitive decline (SCD) has been proposed as a pre-MCI at-risk condition of Alzheimer's disease (AD). Current research is focusing on a refined…”
Get full text

The cholinergic system in mild cognitive impairment and Alzheimer's disease: An in vivo MRI and DTI study by Teipel, Stefan J., Meindl, Thomas, Grinberg, Lea, Grothe, Michel, Cantero, Jose L., Reiser, Maximilian F., Möller, Hans-Jürgen, Heinsen, Helmut, Hampel, Harald

“…Few studies have investigated in vivo changes of the cholinergic basal forebrain in Alzheimer's disease (AD) and amnestic mild cognitive impairment (MCI), an…”
Get full text

CSF phosphorylated tau protein correlates with neocortical neurofibrillary pathology in Alzheimer's disease by Buerger, Katharina, Ewers, Michael, Pirttilä, Tuula, Zinkowski, Raymond, Alafuzoff, Irina, Teipel, Stefan J., DeBernardis, John, Kerkman, Daniel, McCulloch, Cheryl, Soininen, Hilkka, Hampel, Harald

“…Hyperphosphorylated tau protein (P-tau) in CSF is a core biomarker candidate of Alzheimer's disease. Hyperphosphorylation of tau is thought to lead to…”
Get full text

Core candidate neurochemical and imaging biomarkers of Alzheimer’s disease by Hampel, Harald, Bürger, Katharina, Teipel, Stefan J, Bokde, Arun L.W, Zetterberg, Henrik, Blennow, Kaj

“…Abstract Background In the earliest clinical stages of Alzheimer’s disease (AD) when symptoms are mild, clinical diagnosis can be difficult. AD pathology most…”
Get full text

White matter microstructure underlying default mode network connectivity in the human brain by Teipel, Stefan J., Bokde, Arun L.W., Meindl, Thomas, Amaro, Edson, Soldner, Jasmin, Reiser, Maximilian F., Herpertz, Sabine C., Möller, Hans-Jürgen, Hampel, Harald

“…Resting state functional magnetic resonance imaging (fMRI) reveals a distinct network of correlated brain function representing a default mode state of the…”
Get full text

Ethics, design, and implementation criteria of digital assistive technologies for people with dementia from a multiple stakeholder perspective: a qualitative study by Köhler, Stefanie, Perry, Julia, Biernetzky, Olga A, Kirste, Thomas, Teipel, Stefan J

“…Dementia impairs the ability of people with dementia to be autonomous and independent. They need support from third parties, who should ideally respect their…”
Get full text