Search Results - "Teh, Evelyn M"
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1
Comparative performance of different methods for circulating tumor cell enrichment in metastatic breast cancer patients
Published in PloS one (13-08-2020)“…The isolation and analysis of circulating tumor cells (CTC) has the potential to provide minimally invasive diagnostic, prognostic and predictive information…”
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2
Carboxypeptidase A5 identifies a novel mast cell lineage in the zebrafish providing new insight into mast cell fate determination
Published in Blood (01-10-2008)“…Mast cells (MCs) play critical roles in allergy and inflammation, yet their development remains controversial due to limitations posed by traditional animal…”
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3
Identification of the epitope of a monoclonal antibody that disrupts binding of human transferrin to the human transferrin receptor
Published in The FEBS journal (01-12-2005)“…The molecular basis of the transferrin (TF)–transferrin receptor (TFR) interaction is not known. The C‐lobe of TF is required to facilitate binding to the TFR…”
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4
A transgenic zebrafish model expressing KIT‐D816V recapitulates features of aggressive systemic mastocytosis
Published in British journal of haematology (01-10-2014)“…Summary Systemic mastocytosis (SM) is a rare myeloproliferative disease without curative therapy. Despite clinical variability, the majority of patients…”
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5
Zebrafish mast cells possess an FcɛRI-like receptor and participate in innate and adaptive immune responses
Published in Developmental and comparative immunology (2011)“…We previously identified a zebrafish mast cell (MC) lineage and now aim to determine if these cells function analogously in innate and adaptive immunity like…”
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6
Human plasma CETP deficiency: identification of a novel mutation in exon 9 of the CETP gene in a Caucasian subject from North America
Published in Journal of lipid research (01-02-1998)“…Human plasma cholesteryl ester transfer protein (CETP) is a 476-residue hydrophobic glycoprotein that catalyzes the heterotransfer of cholesteryl esters and…”
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7
Novel Ubiquitin Fusion Proteins: Ribosomal Protein P1 and Actin
Published in Journal of molecular biology (09-05-2003)“…Ubiquitin is a small, highly conserved protein found in all eukaryotic cells. Through its covalent attachment to other proteins, ubiquitin regulates numerous…”
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8
Deletion of N-terminal amino acids from human lecithin:cholesterol acyltransferase differentially affects enzyme activity toward α- and β-substrate lipoproteins
Published in Biochimica et biophysica acta (21-03-2003)“…Lecithin:cholesterol acyltransferase (LCAT) is the enzyme responsible for generation of the majority of the cholesteryl esters (CE) in human plasma. Although…”
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A transgenic zebrafish model expressing KIT ‐ D 816 V recapitulates features of aggressive systemic mastocytosis
Published in British journal of haematology (01-10-2014)“…Summary Systemic mastocytosis ( SM ) is a rare myeloproliferative disease without curative therapy. Despite clinical variability, the majority of patients…”
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10
Notch Signaling Is Required for Mast Cell Development In the Zebrafish and May Represent a Novel Therapeutic Strategy In Systemic Mastocytosis
Published in Blood (19-11-2010)“…Abstract 930 We have been exploiting the advantages provided by the zebrafish system to elucidate the molecular pathways regulating mast cell (MC) development…”
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Zebrafish Mast Cells Demonstrate Conserved Innate and Adaptive Immune Responses
Published in Blood (16-11-2008)“…Mast cells (MCs) are multifunctional immune cells derived from hematopoietic stem cells that uniquely complete maturation where they take up residence, namely…”
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Zebrafish mast cells possess an FcRI-like receptor and participate in innate and adaptive immune responses
Published in Developmental and comparative immunology (01-01-2011)“…We previously identified a zebrafish mast cell (MC) lineage and now aim to determine if these cells function analogously in innate and adaptive immunity like…”
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Classical LCAT deficiency resulting from a novel homozygous dinucleotide deletion in exon 4 of the human lecithin: cholesterol acyltransferase gene causing a frameshift and stop codon at residue 144
Published in Atherosclerosis (01-09-1999)“…Lecithin: cholesterolacyltransferase (LCAT) transacylates the fatty acid at the sn-2 position of lecithin to the 3β-OH group of cholesterol forming…”
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14
Linked genes for calmodulin and E2 ubiquitin-conjugating enzyme in Trichomonas vaginalis
Published in The Journal of eukaryotic microbiology (01-11-1996)“…In searching the genomes of early-diverging protists to study whether the possession of calmodulin is ancestral to all eukaryotes, the gene for calmodulin was…”
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