Search Results - "Tedford, Clark E."

Quantitative analysis of transcranial and intraparenchymal light penetration in human cadaver brain tissue by Tedford, Clark E., DeLapp, Scott, Jacques, Steven, Anders, Juanita

“…Background and Objective Photobiomodulation (PBM) also known as low‐level light therapy has been used successfully for the treatment of injury and disease of…”
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Targeting of mannan-binding lectin-associated serine protease-2 confers protection from myocardial and gastrointestinal ischemia/reperfusion injury by Schwaeble, Wilhelm J, Lynch, Nicholas J, Clark, James E, Marber, Michael, Samani, Nilesh J, Ali, Youssif Mohammed, Dudler, Thomas, Parent, Brian, Lhotta, Karl, Wallis, Russell, Farrar, Conrad A, Sacks, Steven, Lee, Haekyung, Zhang, Ming, Iwaki, Daisuke, Takahashi, Minoru, Fujita, Teizo, Tedford, Clark E, Stover, Cordula M

“…Complement research experienced a renaissance with the discovery of a third activation route, the lectin pathway. We developed a unique model of total lectin…”
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LIGHTSITE II Randomized Multicenter Trial: Evaluation of Multiwavelength Photobiomodulation in Non-exudative Age-Related Macular Degeneration by Burton, Ben, Parodi, Maurizio Battaglia, Jürgens, Ignasi, Zanlonghi, Xavier, Hornan, Dan, Roider, Johann, Lorenz, Katrin, Munk, Marion R., Croissant, Cindy L., Tedford, Stephanie E., Walker, Michael, Ruckert, Rene, Tedford, Clark E.

“…Introduction Photobiomodulation (PBM) represents a potential treatment for non-exudative age-related macular degeneration (AMD). PBM uses wavelengths of light…”
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Photobiomodulation use in ophthalmology - an overview of translational research from bench to bedside by Valter, Krisztina, Tedford, Stephanie E, Eells, Janis T, Tedford, Clark E

“…Photobiomodulation (PBM) refers to the process in which wavelengths of light are absorbed by intracellular photoacceptors, resulting in the activation of…”
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A Response to: Letter to the Editor Regarding “LIGHTSITE II Randomized Multicenter Trial: Evaluation of Multiwavelength Photobiomodulation in Non-exudative Age-Related Macular Degeneration” by Burton, Ben, Munk, Marion R., Tedford, Stephanie E., Croissant, Cindy L., Rückert, Rene, Tedford, Clark E.

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" LIGHTSITE III: 13-Month Efficacy and Safety Evaluation of Multiwavelength Photobiomodulation in Nonexudative (Dry) Age-Related Macular Degeneration Using the LumiThera Valeda Light Delivery System " by Boyer, David, Munk, Marion R, Tedford, Stephanie E, Croissant, Cindy L, Rückert, Rene, Tedford, Clark E

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Low-level laser therapy (LLLT) reduces oxidative stress in primary cortical neurons in vitro by Huang, Ying-Ying, Nagata, Kazuya, Tedford, Clark E., McCarthy, Thomas, Hamblin, Michael R.

“…Low‐level laser (light) therapy (LLLT) involves absorption of photons being in the mitochondria of cells leading to improvement in electron transport,…”
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A DOUBLE-MASKED, RANDOMIZED, SHAM-CONTROLLED, SINGLE-CENTER STUDY WITH PHOTOBIOMODULATION FOR THE TREATMENT OF DRY AGE-RELATED MACULAR DEGENERATION by Markowitz, Samuel N., Devenyi, Robert G., Munk, Marion R., Croissant, Cindy L., Tedford, Stephanie E., Rückert, Rene, Walker, Michael G., Patino, Beatriz E., Chen, Lina, Nido, Monica, Tedford, Clark E.

“…The LIGHTSITE I study investigated the efficacy and safety of photobiomodulation (PBM) treatment in subjects with dry age-related macular degeneration. Thirty…”
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LIGHTSITE III: 13-Month Efficacy and Safety Evaluation of Multiwavelength Photobiomodulation in Nonexudative (Dry) Age-Related Macular Degeneration Using the Lumithera Valeda Light Delivery System by Boyer, David, Hu, Allen, Warrow, David, Xavier, Samantha, Gonzalez, Victor, Lad, Eleonora, Rosen, Richard B, Do, Diana, Schneiderman, Todd, Ho, Allen, Munk, Marion R, Jaffe, Glenn, Tedford, Stephanie E, Croissant, Cindy L, Walker, Michael, Rückert, Rene, Tedford, Clark E

“…The LIGHTSITE III study evaluated multiwavelength photobiomodulation (PBM) therapy in nonexudative (dry) age-related macular degeneration (AMD) using the…”
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Low-level laser therapy (810 nm) protects primary cortical neurons against excitotoxicity in vitro by Huang, Ying-Ying, Nagata, Kazuya, Tedford, Clark E, Hamblin, Michael R.

“…Excitotoxicity describes a pathogenic process whereby death of neurons releases large amounts of the excitatory neurotransmitter glutamate, which then proceeds…”
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Non-Invasive Treatment of Early Diabetic Macular Edema by Multiwavelength Photobiomodulation with the Valeda Light Delivery System by Kaymak, Hakan, Munk, Marion R, Tedford, Stephanie E, Croissant, Cindy L, Tedford, Clark E, Ruckert, Rene, Schwahn, Hartmut

“…Purpose: Diabetes is associated with ocular complications including diabetic macular edema (DME). Current therapies are invasive and include repeated…”
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Pulsed Light Irradiation Improves Behavioral Outcome in a Rat Model of Chronic Mild Stress by Wu, Xingjia, Alberico, Stephanie L., Moges, Helina, De Taboada, Luis, Tedford, Clark E., Anders, Juanita J.

“…Background and Objective Transcranial laser therapy (TLT) has been used successfully for the treatment of stroke in animal models and clinical trials. These…”
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Re: "Quantitative analysis of transcranial and intraparenchymal light penetration in human cadaver brain tissue" Lasers in Surgery and Medicine, 2015;47(4):312-322 by Tedford, Clark E., DeLapp, Scott, Jacques, Steven, Anders, Juanita

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Near infrared radiation rescues mitochondrial dysfunction in cortical neurons after oxygen-glucose deprivation by Yu, Zhanyang, Liu, Ning, Zhao, Jianhua, Li, Yadan, McCarthy, Thomas J., Tedford, Clark E., Lo, Eng H., Wang, Xiaoying

“…Near infrared radiation (NIR) is known to penetrate and affect biological systems in multiple ways. Recently, a series of experimental studies suggested that…”
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Design, Synthesis, and Structure−Activity Relationships of Acetylene-Based Histamine H3 Receptor Antagonists by Ali, Syed M, Tedford, Clark E, Gregory, Rosilyn, Handley, Michael K, Yates, Stephen L, Hirth, Walter W, Phillips, James G

“…New, potent, and selective histamine H3 receptor antagonists have been synthesized by employing the use of (1) an appropriately positioned nonpolar acetylene…”
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Near infrared radiation protects against oxygen-glucose deprivation-induced neurotoxicity by down-regulating neuronal nitric oxide synthase (nNOS) activity in vitro by Yu, Zhanyang, Li, Zhaoyu, Liu, Ning, Jizhang, Yunneng, McCarthy, Thomas J., Tedford, Clark E., Lo, Eng H., Wang, Xiaoying

“…Near infrared radiation (NIR) has been shown to be neuroprotective against neurological diseases including stroke and brain trauma, but the underlying…”
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Mirtazapine treatment after conditioning with methamphetamine alters subsequent expression of place preference by Herrold, Amy A, Shen, Fei, Graham, Martin P, Harper, Laura K, Specio, Sheila E, Tedford, Clark E, Napier, T. Celeste

“…Abstract Methamphetamine (MP) is a widely abused psychostimulant. There are currently no FDA approved pharmacotherapies for the MP addict. The antidepressant,…”
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Reply by Boyer, David S., Munk, Marion R., Tedford, Stephanie E., Croissant, Cindy L., Rückert, Rene, Tedford, Clark E.

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High antagonist potency of GT-2227 and GT-2331, new histamine H3 receptor antagonists, in two functional models by TEDFORD, C. E, HOFFMANN, M, SEYEDI, N, MARUYAMA, R, LEVI, R, YATES, S. L, ALI, S. M, PHILLIPS, J. G

“…GT-2227 (4-(6-cyclohexylhex-cis-3-enyl)imidazole) and GT-2331 ((1R,2R)-4-(2-(5,5-dimethylhex-1-ynyl)cyclopropyl)imidazole) were developed as new potent…”
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Identification and pharmacological characterization of a series of new 1H-4-substituted-imidazoyl histamine H3 receptor ligands by Yates, S L, Phillips, J G, Gregory, R, Pawlowski, G P, Fadnis, L, Khan, M A, Ali, S M, Tedford, C E

“…A new series of 1H-4-substituted imidazole compounds were synthesized and identified as potent and selective histamine (HA) H3 receptor ligands. These ligands…”
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