Search Results - "Tebabi, Patricia"

A molecular mechanism for Wnt ligand-specific signaling by Eubelen, Marie, Bostaille, Naguissa, Cabochette, Pauline, Gauquier, Anne, Tebabi, Patricia, Dumitru, Andra C, Koehler, Melanie, Gut, Philipp, Alsteens, David, Stainier, Didier Y R, Garcia-Pino, Abel, Vanhollebeke, Benoit

“…Wnt signaling is key to many developmental, physiological and disease processes, in which cells seem able to discriminate between multiple Wnt ligands. This…”
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Coupling of lysosomal and mitochondrial membrane permeabilization in trypanolysis by APOL1 by Vanwalleghem, Gilles, Fontaine, Frédéric, Lecordier, Laurence, Tebabi, Patricia, Klewe, Kristoffer, Nolan, Derek P., Yamaryo-Botté, Yoshiki, Botté, Cyrille, Kremer, Anneke, Burkard, Gabriela Schumann, Rassow, Joachim, Roditi, Isabel, Pérez-Morga, David, Pays, Etienne

“…Humans resist infection by the African parasite Trypanosoma brucei owing to the trypanolytic activity of the serum apolipoprotein L1 (APOL1). Following uptake…”
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APOL1 C-Terminal Variants May Trigger Kidney Disease through Interference with APOL3 Control of Actomyosin by Uzureau, Sophie, Lecordier, Laurence, Uzureau, Pierrick, Hennig, Dorle, Graversen, Jonas H., Homblé, Fabrice, Mfutu, Pepe Ekulu, Oliveira Arcolino, Fanny, Ramos, Ana Raquel, La Rovere, Rita M., Luyten, Tomas, Vermeersch, Marjorie, Tebabi, Patricia, Dieu, Marc, Cuypers, Bart, Deborggraeve, Stijn, Rabant, Marion, Legendre, Christophe, Moestrup, Søren K., Levtchenko, Elena, Bultynck, Geert, Erneux, Christophe, Pérez-Morga, David, Pays, Etienne

“…The C-terminal variants G1 and G2 of apolipoprotein L1 (APOL1) confer human resistance to the sleeping sickness parasite Trypanosoma rhodesiense, but they also…”
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C-terminal mutants of apolipoprotein L-I efficiently kill both Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense by Lecordier, Laurence, Vanhollebeke, Benoit, Poelvoorde, Philippe, Tebabi, Patricia, Paturiaux-Hanocq, Francoise, Andris, Fabienne, Lins, Laurence, Pays, Etienne

“…Apolipoprotein L-I (apoL1) is a human-specific serum protein that kills Trypanosoma brucei through ionic pore formation in endosomal membranes of the parasite…”
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Apolipoprotein L-I is the trypanosome lytic factor of human serum by Pays, Etienne, Vanhamme, Luc, Paturiaux-Hanocq, Françoise, Poelvoorde, Philippe, Nolan, Derek P, Lins, Laurence, Van Den Abbeele, Jan, Pays, Annette, Tebabi, Patricia, Van Xong, Huang, Jacquet, Alain, Moguilevsky, Nicole, Dieu, Marc, Kane, John P, De Baetselier, Patrick, Brasseur, Robert

“…Human sleeping sickness in east Africa is caused by the parasite Trypanosoma brucei rhodesiense. The basis of this pathology is the resistance of these…”
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The Trypanosoma Brucei KIFC1 Kinesin Ensures the Fast Antibody Clearance Required for Parasite Infectivity by Lecordier, Laurence, Uzureau, Sophie, Vanwalleghem, Gilles, Deleu, Magali, Crowet, Jean-Marc, Barry, Paul, Moran, Barry, Voorheis, Paul, Dumitru, Andra-Cristina, Yamaryo-Botté, Yoshiki, Dieu, Marc, Tebabi, Patricia, Vanhollebeke, Benoit, Lins, Laurence, Botté, Cyrille Y., Alsteens, David, Dufrêne, Yves, Pérez-Morga, David, Nolan, Derek P., Pays, Etienne

“…Human innate immunity to Trypanosoma brucei involves the trypanosome C-terminal kinesin TbKIFC1, which transports internalized trypanolytic factor…”
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Engineered Wnt ligands enable blood-brain barrier repair in neurological disorders by Martin, Maud, Vermeiren, Simon, Bostaille, Naguissa, Eubelen, Marie, Spitzer, Daniel, Vermeersch, Marjorie, Profaci, Caterina P, Pozuelo, Elisa, Toussay, Xavier, Raman-Nair, Joanna, Tebabi, Patricia, America, Michelle, De Groote, Aurélie, Sanderson, Leslie E, Cabochette, Pauline, Germano, Raoul F V, Torres, David, Boutry, Sébastien, de Kerchove d'Exaerde, Alban, Bellefroid, Eric J, Phoenix, Timothy N, Devraj, Kavi, Lacoste, Baptiste, Daneman, Richard, Liebner, Stefan, Vanhollebeke, Benoit

“…The blood-brain barrier (BBB) protects the central nervous system (CNS) from harmful blood-borne factors. Although BBB dysfunction is a hallmark of several…”
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Apolipoprotein L-I Promotes Trypanosome Lysis by Forming Pores in Lysosomal Membranes by Pérez-Morga, David, Vanhollebeke, Benoit, Paturiaux-Hanocq, Françoise, Nolan, Derek P, Lins, Laurence, Homblé, Fabrice, Vanhamme, Luc, Tebabi, Patricia, Pays, Annette, Poelvoorde, Philippe, Jacquet, Alain, Brasseur, Robert, Pays, Etienne

“…Apolipoprotein L-I is the trypanolytic factor of human serum. Here we show that this protein contains a membrane pore-forming domain functionally similar to…”
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Haptoglobin-Hemoglobin Receptor Conveys Innate Immunity to Trypanosoma brucei in Humans by Vanhollebeke, Benoit, De Muylder, Géraldine, Nielsen, Marianne J, Pays, Annette, Tebabi, Patricia, Dieu, Marc, Raes, Martine, Moestrup, Soren K, Pays, Etienne

“…The protozoan parasite Trypanosoma brucei is lysed by apolipoprotein L-I, a component of human high-density lipoprotein (HDL) particles that are also…”
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Mechanism of Trypanosoma brucei gambiense resistance to human serum by Uzureau, Pierrick, Uzureau, Sophie, Lecordier, Laurence, Fontaine, Frédéric, Tebabi, Patricia, Homblé, Fabrice, Grélard, Axelle, Zhendre, Vanessa, Nolan, Derek P., Lins, Laurence, Crowet, Jean-Marc, Pays, Annette, Felu, Cécile, Poelvoorde, Philippe, Vanhollebeke, Benoit, Moestrup, Soren K., Lyngsø, Jeppe, Pedersen, Jan Skov, Mottram, Jeremy C., Dufourc, Erick J., Pérez-Morga, David, Pays, Etienne

“…This study shows that Trypanosoma brucei gambiense resists trypanolytic factors (TLFs) in a multifactorial manner, relying on a hydrophobic β-sheet of the…”
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Adaptation of Trypanosoma rhodesiense to hypohaptoglobinaemic serum requires transcription of the APOL1 resistance gene in a RNA polymerase I locus by Lecordier, Laurence, Uzureau, Pierrick, Tebabi, Patricia, Brauner, Jonathan, Benghiat, Fleur Samantha, Vanhollebeke, Benoit, Pays, Etienne

“…Summary Human apolipoprotein L1 (APOL1) kills African trypanosomes except Trypanosoma rhodesiense and Trypanosoma gambiense, the parasites causing sleeping…”
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Adaptation of T rypanosoma rhodesiense to hypohaptoglobinaemic serum requires transcription of the APOL 1 resistance gene in a RNA polymerase I locus by Lecordier, Laurence, Uzureau, Pierrick, Tebabi, Patricia, Brauner, Jonathan, Benghiat, Fleur Samantha, Vanhollebeke, Benoit, Pays, Etienne

“…Summary Human apolipoprotein L 1 ( APOL 1) kills African trypanosomes except T rypanosoma rhodesiense and T rypanosoma gambiense , the parasites causing…”
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Apolipoprotein L-1 Promotes Trypanosome Lysis By Forming Pores In Lysosomal Membranes by Perez-Morga, David, Vanhollebeke, Benoit, Paturiaux-Hanocq, Françoise, Nolan, Derek P., Lins, Laurence, Homble, Fabrice, Vanhamme, Luc, Tebabi, Patricia, Pays, Annette, Poelvoorde, Philippe, Jacquet, Alain, Brasseur, Robert, Pays, Etienne

“…Apolipoprotein L-I is the trypanolytic factor of human serum. Here we show that this protein contains a membrane pore-forming domain functionally similar to…”
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Identification of Trypanosoma brucei components involved in trypanolysis by normal human serum by Lecordier, Laurence, Uzureau, Pierrick, Tebabi, Patricia, Pérez‐Morga, David, Nolan, Derek, Schumann Burkard, Gabriela, Roditi, Isabel, Pays, Etienne

“…Summary Normal human serum (NHS) confers human resistance to infection by the parasite Trypanosoma brucei owing to the trypanolytic activity of apolipoprotein…”
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Identification of T rypanosoma brucei components involved in trypanolysis by normal human serum by Lecordier, Laurence, Uzureau, Pierrick, Tebabi, Patricia, Pérez‐Morga, David, Nolan, Derek, Schumann Burkard, Gabriela, Roditi, Isabel, Pays, Etienne

“…Summary Normal human serum ( NHS ) confers human resistance to infection by the parasite T rypanosoma brucei owing to the trypanolytic activity of…”
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APOLs with low pH dependence can kill all African trypanosomes by Fontaine, Frédéric, Lecordier, Laurence, Vanwalleghem, Gilles, Uzureau, Pierrick, Van Reet, Nick, Fontaine, Martina, Tebabi, Patricia, Vanhollebeke, Benoit, Büscher, Philippe, Pérez-Morga, David, Pays, Etienne

“…The primate-specific serum protein apolipoprotein L1 (APOL1) is the only secreted member of a family of cell death promoting proteins 1 – 4 . APOL1 kills the…”
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A chromosomal SIR2 homologue with both histone NAD-dependent ADP-ribosyltransferase and deacetylase activities is involved in DNA repair in Trypanosoma brucei by García-Salcedo, José A., Gijón, Purificación, Nolan, Derek P., Tebabi, Patricia, Pays, Etienne

“…SIR2‐like proteins have been implicated in a wide range of cellular events including chromosome silencing, chromosome segregation, DNA recombination and the…”
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A molecular mechanism for Wnt ligand-specific signaling by Eubelen, Marie, Bostaille, Naguissa, Cabochette, Pauline, Gauquier, Anne, Tebabi, Patricia, Dumitru, Andra-Cristina, Kohler, Melanie, Gut, Philipp, Alsteens, David, Stainier, Didier, Garcia Pino, Abel, Vanhollebeke, Benoit

“…Abstract only…”
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C-Terminal Mutants of Apolipoprotein L-I Efficiently Kill Both Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense: e1000685 by Lecordier, Laurence, Vanhollebeke, Benoit, Poelvoorde, Philippe, Tebabi, Patricia, Paturiaux-Hanocq, Françoise, Andris, Fabienne, Lins, Laurence, Pays, Etienne

“…Apolipoprotein L-I (apoL1) is a human-specific serum protein that kills Trypanosoma brucei through ionic pore formation in endosomal membranes of the parasite…”
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Differential RNA elongation controls the variant surface glycoprotein gene expression sites of Trypanosoma brucei by Vanhamme, L, Poelvoorde, P, Pays, A, Tebabi, P, Xong, H.V, Pays, E

“…The protozoan parasite Trypanosoma brucei develops antigenic variation to escape the immune response of its host. To this end, the trypanosome genome contains…”
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