Search Results - "Teare, M.D"

Genetic Heterogeneity and Penetrance Analysis of the BRCA1 and BRCA2 Genes in Breast Cancer Families by Ford, D., Easton, D.F., Stratton, M., Narod, S., Goldgar, D., Devilee, P., Bishop, D.T., Weber, B., Lenoir, G., Chang-Claude, J., Sobol, H., Teare, M.D., Struewing, J., Arason, A., Scherneck, S., Peto, J., Rebbeck, T.R., Tonin, P., Neuhausen, S., Barkardottir, R., Eyfjord, J., Lynch, H., Ponder, B.A.J., Gayther, S.A., Birch, J.M., Lindblom, A., Stoppa-Lyonnet, D., Bignon, Y., Borg, A., Hamann, U., Haites, N., Scott, R.J., Maugard, C.M., Vasen, H., Seitz, S., Cannon-Albright, L.A., Schofield, A., Zelada-Hedman, M.

“…The contribution of BRCA1 and BRCA2 to inherited breast cancer was assessed by linkage and mutation analysis in 237 families, each with at least four cases of…”
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Airway clearance techniques used by people with cystic fibrosis in the UK by Hoo, Z.H, Daniels, T, Wildman, M.J, Teare, M.D, Bradley, J.M

“…Abstract Objectives To describe the current use of airway clearance techniques among people with cystic fibrosis (CF) in the UK, and the baseline…”
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288 Airway clearance techniques used by people with cystic fibrosis in the UK by Hoo, Z.H, Daniels, T, Wildman, M, Teare, M.D, Bradley, J.M

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358 CF registry mortality analysis to understand the effects of widespread genetic testing on the trend of median age at death: Is the increased life-expectancy related to increased prevalence of mild phenotypes? by Hoo, Z.H, Wildman, M, Teare, M.D

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Exploration of the impact of ‘mild phenotypes’ ON median age at death IN the UK CF registry by Hoo, Z.H, Wildman, M.J, Teare, M.D

“…Summary Background The widespread availability of genetic testing allowing the identification of “milder” individuals with CF coincided with improvements in CF…”
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The angiotensin-converting enzyme gene insertion/deletion polymorphism in Indian patients with vitiligo: a case-control study and meta-analysis: ACE gene I/D polymorphism in vitiligo by Patwardhan, M., Pradhan, V., Taylor, L.H., Thakkar, V., Kharkar, V., Khopkar, U., Ghosh, K., Gawkrodger, D.J., Teare, M.D., Weetman, A.P., Kemp, E.H.

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The angiotensin-converting enzyme gene insertion/deletion polymorphism in Indian patients with vitiligo: a case-control study and meta-analysis by Patwardhan, M., Pradhan, V., Taylor, L.H., Thakkar, V., Kharkar, V., Khopkar, U., Ghosh, K., Gawkrodger, D.J., Teare, M.D., Weetman, A.P., Kemp, E.H.

“…Summary Background  Vitiligo is a common, acquired, idiopathic depigmenting skin disorder. Although the exact pathogenesis remains unknown, genetic…”
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An Expectation-Maximization Algorithm for the Analysis of Allelic Expression Imbalance by Teare, M.D., Heighway, J., Santibáñez Koref, M.F.

“…A significant proportion of the variation between individuals in gene expression levels is genetic, and it is likely that these differences correlate with…”
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Family based studies and genetic epidemiology: theory and practice by Barrett, J H, Sheehan, N A, Cox, A, Worthington, J, Cannings, C, Teare, M D

“…Family based studies have underpinned many successes in uncovering the causes of monogenic and oligogenic diseases. Now research is focussing on the…”
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Clinical and genetic heterogeneity in peroneal muscular atrophy associated with vocal cord weakness by McEntagart, M, Dunstan, M, Bell, C, Boltshauser, E, Donaghy, M, Harper, P S, Williams, N, Teare, M D, Rahman, N

“…Background: The peroneal muscular atrophy syndrome is the most common inherited disorder of the peripheral nervous system and has extensive clinical and…”
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Analysis of Genetic Linkage and Somatic Loss of Heterozygosity in Affected Pairs of First-Degree Relatives by Rohde, K., Teare, M.D., Koref, M. Santibáñez

“…Recently, data on loss of constitutional heterozygosity (LOH) have been used by several groups to increase the power to detect linkage in pedigrees with an…”
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A program using loss-of-constitutional-heterozygosity data to ascertain the location of predisposing genes in cancer families by Rohde, K, Teare, M D, Scherneck, S, Santibáñez Koref, M

“…We present a modification of the MLINK program, which enables the formal incorporation of data on loss of constitutional heterozygosity (LOCH) into likelihood…”
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A linkage study in seven breast cancer families by Teare, M D, Santibáñez-Koref, M F, Wallace, S A, White, G R, Evans, D G, Burnell, L D, Harris, M, Howell, A, Birch, J M

“…Seven breast cancer families are examined for evidence of linkage to a site in the region of 17q12-q21, by using five markers. The families constitute a subset…”
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