Search Results - "TeKoppele, JM"

MMP protein and activity levels in synovial fluid from patients with joint injury, inflammatory arthritis, and osteoarthritis by Tchetverikov, I, Lohmander, L S, Verzijl, N, Huizinga, T W J, TeKoppele, J M, Hanemaaijer, R, DeGroot, J

“…Objective: To determine protein and activity levels of matrix metalloproteinases 1 and 3 (MMP-1 and MMP-3) in synovial fluid of patients with knee joint…”
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Effect of Collagen Turnover on the Accumulation of Advanced Glycation End Products by Verzijl, Nicole, DeGroot, Jeroen, Thorpe, Suzanne R., Bank, Ruud A., Shaw, J. Nikki, Lyons, Timothy J., Bijlsma, Johannes W.J., Lafeber, Floris P.J.G., Baynes, John W., TeKoppele, Johan M.

“…Collagen molecules in articular cartilage have an exceptionally long lifetime, which makes them susceptible to the accumulation of advanced glycation end…”
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Identification of PLOD2 as Telopeptide Lysyl Hydroxylase, an Important Enzyme in Fibrosis by van der Slot, Annemarie J., Zuurmond, Anne-Marie, Bardoel, Alfons F.J., Wijmenga, Cisca, Pruijs, Hans E.H., Sillence, David O., Brinckmann, Jürgen, Abraham, David J., Black, Carol M., Verzijl, Nicole, DeGroot, Jeroen, Hanemaaijer, Roeland, TeKoppele, Johan M., Huizinga, Tom W.J., Bank, Ruud A.

“…The hallmark of fibrotic processes is an excessive accumulation of collagen. The deposited collagen shows an increase in pyridinoline cross-links, which are…”
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The role of collagen in determining bone mechanical properties by Wang, Xiaodu, Bank, Ruud A, TeKoppele, Johan M, Mauli Agrawal, C

“…The hypothesis of this study was that collagen denaturation would lead to a significant decrease in the toughness of bone, but has little effect on the…”
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MMP profile in paired serum and synovial fluid samples of patients with rheumatoid arthritis by Tchetverikov, I, Ronday, H K, van El, B, Kiers, G H, Verzijl, N, TeKoppele, J M, Huizinga, T W J, DeGroot, J, Hanemaaijer, R

“…Objective: To analyse matrix metalloproteinases (MMPs) and tissue inhibitor-1 of MMPs (TIMP-1) levels in the systemic circulation and synovial fluid (SF) of…”
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AGEing and osteoarthritis: a different perspective by Verzijl, Nicole, Bank, Ruud A, TeKoppele, Johan M, DeGroot, Jeroen

“…PURPOSE OF REVIEWAcross the world, osteoarthritis is the most commonly occurring musculoskeletal disease of the elderly, affecting more than 25% of the…”
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Extracellular mitochondrial DNA and oxidatively damaged DNA in synovial fluid of patients with rheumatoid arthritis by Hajizadeh, Shahin, DeGroot, Jeroen, TeKoppele, Johan M, Tarkowski, Andrej, Collins, L Vincent

“…We investigated whether plasma and synovial fluid (SF) samples from patients with rheumatoid arthritis (RA) contained extracellular mitochondrial DNA (mtDNA)…”
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Advanced glycation end product ligands for the receptor for advanced glycation end products: biochemical characterization and formation kinetics by Valencia, Jessica V, Weldon, Stephen C, Quinn, Douglas, Kiers, Geesje H, DeGroot, Jeroen, TeKoppele, Johan M, Hughes, Thomas E

“…Advanced glycation end products (AGEs) accumulate with age and at an accelerated rate in diabetes. AGEs bind cell-surface receptors including the receptor for…”
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Age-related accumulation of Maillard reaction products in human articular cartilage collagen by Verzijl, N, DeGroot, J, Oldehinkel, E, Bank, R A, Thorpe, S R, Baynes, J W, Bayliss, M T, Bijlsma, J W, Lafeber, F P, Tekoppele, J M

“…Non-enzymic modification of tissue proteins by reducing sugars, the so-called Maillard reaction, is a prominent feature of aging. In articular cartilage,…”
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Matrix metalloproteinases-3, -8, -9 as markers of disease activity and joint damage progression in early rheumatoid arthritis by Tchetverikov, I, Lard, L R, DeGroot, J, Verzijl, N, TeKoppele, J M, Breedveld, F C, Huizinga, T W J, Hanemaaijer, R

“…Objective: To analyse the relation between systemic levels of pro-MMP-3, -8, and -9 matrix metalloproteinase (MMP) activity in α2 macroglobulin (α2M)/MMP…”
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A comparative analysis of bone and cartilage metabolism in two strains of guinea-pig with varying degrees of naturally occurring osteoarthritis by Huebner, J.L., Hanes, M.A., Beekman, B., TeKoppele, J.M., Kraus, V.B.

“…Objective To evaluate the interaction of bone and cartilage in knee osteoarthritis (OA) pathogenesis in two guinea-pig strains with appreciable differences in…”
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Ageing and zonal variation in post-translational modification of collagen in normal human articular cartilage. The age-related increase in non-enzymatic glycation affects biomechanical properties of cartilage by Bank, R A, Bayliss, M T, Lafeber, F P, Maroudas, A, Tekoppele, J M

“…A biomechanical failure of the collagen network is postulated in many hypotheses of the development of osteoarthritis with advancing age. Here we investigate…”
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The canine ‘groove’ model, compared with the ACLT model of osteoarthritis by Marijnissen, A.C.A., van Roermund, P.M., TeKoppele, J.M., Bijlsma, J.W.J., Lafeber, F.P.J.G.

“…Objective The frequently used anterior cruciate ligament transection (ACLT) model of osteoarthritis (OA) in the dog, makes use of a permanent trigger (joint…”
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Accumulation of advanced glycation endproducts reduces chondrocyte-mediated extracellular matrix turnover in human articular cartilage by DeGroot, J., Verzijl, N., Jacobs, K.M.G., Budde, M., Bank, R.A., Bijlsma, J.W.J., TeKoppele, J.M., Lafeber, F.P.J.G.

“…Objective The prevalence of osteoarthritis (OAs) increases with age and coincides with the accumulation of advanced glycation endproducts (AGEs) in articular…”
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Compositional and metabolic changes in damaged cartilage are peak-stress, stress-rate, and loading-duration dependent by Chen, C T, Burton-Wurster, N, Lust, G, Bank, R A, Tekoppele, J M

“…The first objective of this study was to determine if the cumulative effects of impact or smoothly arising compression would damage the matrix of articular…”
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Defective Collagen Crosslinking in Bone, but Not in Ligament or Cartilage, in Bruck Syndrome: Indications for a Bone-Specific Telopeptide Lysyl Hydroxylase on Chromosome 17 by Bank, Ruud A., Robins, Simon P., Wijmenga, Cisca, Breslau-Siderius, Liesbeth J., Alfons F. J. Bardoel, Van der Sluijs, Hans A., Hans E. H. Pruijs, TeKoppele, Johan M.

“…Bruck syndrome is characterized by the presence of osteoporosis, joint contractures, fragile bones, and short stature. We report that lysine residues within…”
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Identification of disease- and nutrient-related metabolic fingerprints in osteoarthritic Guinea pigs by Lamers, Robert-Jan A N, DeGroot, Jeroen, Spies-Faber, Elly J, Jellema, Renger H, Kraus, Virginia B, Verzijl, Nicole, TeKoppele, Johan M, Spijksma, Gerwin K, Vogels, Jack T W E, van der Greef, Jan, van Nesselrooij, Joop H J

“…Osteoarthritis (OA), one of the most common diseases among the elderly, is characterized by the progressive destruction of joint tissues. Its etiology is…”
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Age-related accumulation of the advanced glycation endproduct pentosidine in human articular cartilage aggrecan: the use of pentosidine levels as a quantitative measure of protein turnover by Verzijl, Nicole, DeGroot, Jeroen, Bank, Ruud A., Bayliss, Michael T., Bijlsma, Johannes W.J., Lafeber, Floris P.J.G., Maroudas, Alice, TeKoppele, Johan M.

“…During aging, non-enzymatic glycation results in the formation and accumulation of the advanced glycation endproduct pentosidine in long-lived proteins, such…”
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Accumulation of Advanced Glycation End Products Decreases Collagen Turnover by Bovine Chondrocytes by DeGroot, Jeroen, Verzijl, Nicole, Budde, Marianne, Bijlsma, Johannes W.J., Lafeber, Floris P.J.G., TeKoppele, Johan M.

“…The integrity of the collagen network is essential for articular cartilage to fulfill its function in load support and distribution. Damage to the collagen…”
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Functional adaptation of equine articular cartilage: the formation of regional biochemical characteristics up to age one year by Brama, P. A. J., Tekoppele, J. M., Bank, R. A., Barneveld, A., Van Weeren, P. R.

“…Summary Biochemical heterogeneity of cartilage within a joint is well known in mature individuals. It has recently been reported that heterogeneity…”
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