Search Results - "Tayrac, Marie de"

MITF reprograms the extracellular matrix and focal adhesion in melanoma by Dilshat, Ramile, Fock, Valerie, Kenny, Colin, Gerritsen, Ilse, Lasseur, Romain Maurice Jacques, Travnickova, Jana, Eichhoff, Ossia M, Cerny, Philipp, Möller, Katrin, Sigurbjörnsdóttir, Sara, Kirty, Kritika, Einarsdottir, Berglind Ósk, Cheng, Phil F, Levesque, Mitchell, Cornell, Robert A, Patton, E Elizabeth, Larue, Lionel, de Tayrac, Marie, Magnúsdóttir, Erna, Ögmundsdóttir, Margrét Helga, Steingrimsson, Eirikur

“…The microphthalmia-associated transcription factor (MITF) is a critical regulator of melanocyte development and differentiation. It also plays an important…”
Get full text

DNA methylation in glioblastoma: impact on gene expression and clinical outcome by Etcheverry, Amandine, Aubry, Marc, de Tayrac, Marie, Vauleon, Elodie, Boniface, Rachel, Guenot, Frederique, Saikali, Stephan, Hamlat, Abderrahmane, Riffaud, Laurent, Menei, Philippe, Quillien, Veronique, Mosser, Jean

“…Changes in promoter DNA methylation pattern of genes involved in key biological pathways have been reported in glioblastoma. Genome-wide assessments of DNA…”
Get full text

Automated Analysis of 1p/19q Status by FISH in Oligodendroglial Tumors: Rationale and Proposal of an Algorithm by Duval, Céline, de Tayrac, Marie, Michaud, Karine, Cabillic, Florian, Paquet, Claudie, Gould, Peter Vincent, Saikali, Stéphan

“…To propose a new algorithm facilitating automated analysis of 1p and 19q status by FISH technique in oligodendroglial tumors with software packages available…”
Get full text

Contribution of 1p, 19q, 9p and 10q Automated Analysis by FISH to the Diagnosis and Prognosis of Oligodendroglial Tumors According to WHO 2016 Guidelines by Michaud, Karine, de Tayrac, Marie, D'Astous, Myreille, Duval, Céline, Paquet, Claudie, Samassekou, Oumar, Gould, Peter Vincent, Saikali, Stéphan

“…To study the feasibility and the diagnostic and prognostic interest of automated analysis of 1p, 19q, 9p and 10q status by FISH technique in oligodendroglial…”
Get full text

Implementation of a molecular tumor board at a regional level to improve access to targeted therapy by Bourien, Héloïse, Lespagnol, Alexandra, Campillo-Gimenez, Boris, Felten-Vinot, Ingrid, Metges, Jean-Philippe, Corre, Romain, Lesimple, Thierry, le Marechal, Cédric, Boussemart, Lise, Kammerer-Jacquet, Solène-Florence, le Gall, Edouard, Denoual, Florent, de Tayrac, Marie, Galibert, Marie-Dominique, Mosser, Jean, Edeline, Julien

“…Background With the development of precision oncology, Molecular Tumor Boards (MTB) are developing in many institutions. However, the implementation of MTB in…”
Get full text

ImmunoFISH is a reliable technique for the assessment of 1p and 19q status in oligodendrogliomas by Duval, Céline, de Tayrac, Marie, Sanschagrin, François, Michaud, Karine, Gould, Peter Vincent, Saikali, Stéphan

“…To develop a new ImmunoFISH technique for the study of oligodendrogliomas by combining a standard immunohistochemical stain using MIB-1 antibody with a…”
Get full text

Five distinct biological processes and 14 differentially expressed genes characterize TEL/AML1-positive leukemia by Gandemer, Virginie, Rio, Anne-Gaëlle, de Tayrac, Marie, Sibut, Vonnick, Mottier, Stéphanie, Ly Sunnaram, Béatrice, Henry, Catherine, Monnier, Annabelle, Berthou, Christian, Le Gall, Edouard, Le Treut, André, Schmitt, Claudine, Le Gall, Jean-Yves, Mosser, Jean, Galibert, Marie-Dominique

“…The t(12;21)(p13;q22) translocation is found in 20 to 25% of cases of childhood B-lineage acute lymphoblastic leukemia (B-ALL). This rearrangement results in…”
Get full text

GNPAT Variant associated with severe iron overload in HFE hemochromatosis by Bardou‐Jacquet, Edouard, de Tayrac, Marie, Mosser, Jean, Deugnier, Yves

Get full text

Disrupted Hypothalamo-Pituitary Axis in Association With Reduced SHH Underlies the Pathogenesis of NOTCH-Deficiency by Hamdi-Rozé, Houda, Ware, Michelle, Guyodo, Hélène, Rizzo, Aurélie, Ratié, Leslie, Rupin, Maïlys, Carré, Wilfrid, Kim, Artem, Odent, Sylvie, Dubourg, Christèle, David, Véronique, de Tayrac, Marie, Dupé, Valérie

“…In human, Sonic hedgehog (SHH) haploinsufficiency is the predominant cause of holoprosencephaly, a structural malformation of the forebrain midline…”
Get full text

Depicting the genetic architecture of pediatric cancers through an integrative gene network approach by Savary, Clara, Kim, Artem, Lespagnol, Alexandra, Gandemer, Virginie, Pellier, Isabelle, Andrieu, Charlotte, Pagès, Gilles, Galibert, Marie-Dominique, Blum, Yuna, de Tayrac, Marie

“…The genetic etiology of childhood cancers still remains largely unknown. It is therefore essential to develop novel strategies to unravel the spectrum of…”
Get full text

Mutational Spectrum in Holoprosencephaly Shows That FGF is a New Major Signaling Pathway by Dubourg, Christèle, Carré, Wilfrid, Hamdi-Rozé, Houda, Mouden, Charlotte, Roume, Joëlle, Abdelmajid, Benmansour, Amram, Daniel, Baumann, Clarisse, Chassaing, Nicolas, Coubes, Christine, Faivre-Olivier, Laurence, Ginglinger, Emmanuelle, Gonzales, Marie, Levy-Mozziconacci, Annie, Lynch, Sally-Ann, Naudion, Sophie, Pasquier, Laurent, Poidvin, Amélie, Prieur, Fabienne, Sarda, Pierre, Toutain, Annick, Dupé, Valérie, Akloul, Linda, Odent, Sylvie, de Tayrac, Marie, David, Véronique

“…ABSTRACT Holoprosencephaly (HPE) is the most common congenital cerebral malformation in humans, characterized by impaired forebrain cleavage and midline facial…”
Get full text

A framework for validating AI in precision medicine: considerations from the European ITFoC consortium by Tsopra, Rosy, Fernandez, Xose, Luchinat, Claudio, Alberghina, Lilia, Lehrach, Hans, Vanoni, Marco, Dreher, Felix, Sezerman, O.Ugur, Cuggia, Marc, de Tayrac, Marie, Miklasevics, Edvins, Itu, Lucian Mihai, Geanta, Marius, Ogilvie, Lesley, Godey, Florence, Boldisor, Cristian Nicolae, Campillo-Gimenez, Boris, Cioroboiu, Cosmina, Ciusdel, Costin Florian, Coman, Simona, Hijano Cubelos, Oliver, Itu, Alina, Lange, Bodo, Le Gallo, Matthieu, Lespagnol, Alexandra, Mauri, Giancarlo, Soykam, H.Okan, Rance, Bastien, Turano, Paola, Tenori, Leonardo, Vignoli, Alessia, Wierling, Christoph, Benhabiles, Nora, Burgun, Anita

“…Background Artificial intelligence (AI) has the potential to transform our healthcare systems significantly. New AI technologies based on machine learning…”
Get full text

Characterizing the peritumoral brain zone in glioblastoma: a multidisciplinary analysis by Lemée, Jean-Michel, Clavreul, Anne, Aubry, Marc, Com, Emmanuelle, de Tayrac, Marie, Eliat, Pierre-Antoine, Henry, Cécile, Rousseau, Audrey, Mosser, Jean, Menei, Philippe

“…Glioblastoma (GB) is the most frequent and aggressive type of primary brain tumor. Recurrences are mostly located at the margin of the resection cavity in the…”
Get full text

Simultaneous analysis of distinct Omics data sets with integration of biological knowledge: Multiple Factor Analysis approach by de Tayrac, Marie, Lê, Sébastien, Aubry, Marc, Mosser, Jean, Husson, François

“…Genomic analysis will greatly benefit from considering in a global way various sources of molecular data with the related biological knowledge. It is thus of…”
Get full text

Prognostic significance of EDN/RB, HJURP, p60/CAF-1 and PDLI4, four new markers in high-grade gliomas by de Tayrac, Marie, Saikali, Stephan, Aubry, Marc, Bellaud, Pascale, Boniface, Rachel, Quillien, Véronique, Mosser, Jean

“…Recent studies have highlighted the heterogeneity of gliomas and demonstrated that molecular and genetic analysis could help in their classification and in the…”
Get full text

Impact of 9p deletion and p16, Cyclin D1, and Myc hyperexpression on the outcome of anaplastic oligodendrogliomas by Michaud, Karine, de Tayrac, Marie, D'Astous, Myreille, Paquet, Claudie, Gould, Peter Vincent, Saikali, Stéphan

“…To study the presence of 9p deletion and p16, cyclin D1 and Myc expression and their respective diagnostic and prognostic interest in oligodendrogliomas. We…”
Get full text

Genome-wide association study identifies TF as a significant modifier gene of iron metabolism in HFE hemochromatosis by de Tayrac, Marie, Roth, Marie-Paule, Jouanolle, Anne-Marie, Coppin, Hélène, le Gac, Gérald, Piperno, Alberto, Férec, Claude, Pelucchi, Sara, Scotet, Virginie, Bardou-Jacquet, Edouard, Ropert, Martine, Bouvet, Régis, Génin, Emmanuelle, Mosser, Jean, Deugnier, Yves

“…Background & Aims Hereditary hemochromatosis (HH) is the most common form of genetic iron loading disease. It is mainly related to the homozygous C282Y/C282Y…”
Get full text

Homozygous STIL mutation causes holoprosencephaly and microcephaly in two siblings by Mouden, Charlotte, de Tayrac, Marie, Dubourg, Christèle, Rose, Sophie, Carré, Wilfrid, Hamdi-Rozé, Houda, Babron, Marie-Claude, Akloul, Linda, Héron-Longe, Bénédicte, Odent, Sylvie, Dupé, Valérie, Giet, Régis, David, Véronique

“…Holoprosencephaly (HPE) is a frequent congenital malformation of the brain characterized by impaired forebrain cleavage and midline facial anomalies…”
Get full text

DGKI methylation status modulates the prognostic value of MGMT in glioblastoma patients treated with combined radio-chemotherapy with temozolomide by Etcheverry, Amandine, Aubry, Marc, Idbaih, Ahmed, Vauleon, Elodie, Marie, Yannick, Menei, Philippe, Boniface, Rachel, Figarella-Branger, Dominique, Karayan-Tapon, Lucie, Quillien, Veronique, Sanson, Marc, de Tayrac, Marie, Delattre, Jean-Yves, Mosser, Jean

“…Consistently reported prognostic factors for glioblastoma (GBM) are age, extent of surgery, performance status, IDH1 mutational status, and MGMT promoter…”
Get full text

Mouse genetic background impacts both on iron and non-iron metals parameters and on their relationships by Cavey, Thibault, Ropert, Martine, de Tayrac, Marie, Bardou-Jacquet, Edouard, Island, Marie-Laure, Leroyer, Patricia, Bendavid, Claude, Brissot, Pierre, Loréal, Olivier

“…Iron is reported to interact with other metals. In addition, it has been shown that genetic background may impact iron metabolism. Our objective was to…”
Get full text