Search Results - "Taylor, Wayne E."

Androgens Stimulate Myogenic Differentiation and Inhibit Adipogenesis in C3H 10T1/2 Pluripotent Cells through an Androgen Receptor-Mediated Pathway by Singh, Rajan, Artaza, Jorge N, Taylor, Wayne E, Gonzalez-Cadavid, Nestor F, Bhasin, Shalender

“…Testosterone supplementation increases skeletal muscle mass and decreases fat mass; however, the underlying mechanisms are unknown. We hypothesized that…”
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Myostatin inhibits cell proliferation and protein synthesis in C2C12 muscle cells by Taylor, W E, Bhasin, S, Artaza, J, Byhower, F, Azam, M, Willard, Jr, D H, Kull, Jr, F C, Gonzalez-Cadavid, N

“…Myostatin mutations in mice and cattle are associated with increased muscularity, suggesting that myostatin is a negative regulator of skeletal muscle mass. To…”
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Organization of the Human Myostatin Gene and Expression in Healthy Men and HIV-Infected Men with Muscle Wasting by Gonzalez-Cadavid, Nestor F., Taylor, Wayne E., Yarasheski, Kevin, Sinha-Hikim, Indrani, Ma, Kun, Ezzat, Shereen, Shen, Ruoqing, Lalani, Rukhsana, Asa, Sylvia, Mamita, Mohamad, Nair, Gouri, Arver, Stefan, Bhasin, Shalender

“…Myostatin, a member of the transforming growth factor-β superfamily, is a genetic determinant of skeletal muscle growth. Mice and cattle with inactivating…”
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Skeletal muscle mRNA for IGF-IEa, IGF-II, and IGF-I receptor is decreased in sedentary chronic hemodialysis patients by Wang, Huiyuan, Casaburi, Richard, Taylor, Wayne E., Aboellail, Hesham, Storer, Thomas W., Kopple, Joel D.

“…Skeletal muscle mRNA for IGF-IEa, IGF-II, and IGF-I receptor is decreased in sedentary chronic hemodialysis patients. Maintenance hemodialysis patients often…”
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Testosterone Inhibits Adipogenic Differentiation in 3T3-L1 Cells: Nuclear Translocation of Androgen Receptor Complex with β-Catenin and T-Cell Factor 4 May Bypass Canonical Wnt Signaling to Down-Regulate Adipogenic Transcription Factors by Singh, Rajan, Artaza, Jorge N, Taylor, Wayne E, Braga, Melissa, Yuan, Xin, Gonzalez-Cadavid, Nestor F, Bhasin, Shalender

“…Testosterone supplementation in men decreases fat mass; however, the mechanisms by which it inhibits fat mass are unknown. We hypothesized that testosterone…”
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Regulation of Myogenic Differentiation by Androgens: Cross Talk between Androgen Receptor/ β-Catenin and Follistatin/Transforming Growth Factor-β Signaling Pathways by Singh, Rajan, Bhasin, Shalender, Braga, Melissa, Artaza, Jorge N, Pervin, Shehla, Taylor, Wayne E, Krishnan, Venkatesh, Sinha, Satyesh K, Rajavashisth, Tripathi B, Jasuja, Ravi

“…Androgens are important regulators of body composition and promote myogenic differentiation and inhibit adipogenesis of mesenchymal, multipotent cells. Here,…”
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Human KIT ligand promoter is positively regulated by HMGA1 in breast and ovarian cancer cells by TREFF, Nathan R, DEMENT, Gregory A, ADAIR, Jennifer E, BRITT, Rachel L, RONG NIE, SHIMA, James E, TAYLOR, Wayne E, REEVES, Raymond

“…KIT ligand (KL) and its receptor, c-kit, are coexpressed in many types of cancer cells and have been implicated in tumor growth and angiogenesis. While Sertoli…”
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Androgen Receptor in Human Skeletal Muscle and Cultured Muscle Satellite Cells: Up-Regulation by Androgen Treatment by Sinha-Hikim, Indrani, Taylor, Wayne E., Gonzalez-Cadavid, Nestor F., Zheng, Wei, Bhasin, Shalender

“…Androgens stimulate myogenesis, but we do not know what cell types within human skeletal muscle express the androgen receptor (AR) protein and are the target…”
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The effect of glutamine on prevention of glucocorticoid-induced skeletal muscle atrophy is associated with myostatin suppression by Salehian, Behrouz, Mahabadi, Vahid, Bilas, Josephine, Taylor, Wayne E., Ma, Kun

“…Excess glucocorticoids (GCs) cause muscle atrophy. Glucocorticoid-induced muscle atrophy is associated with increased intramuscular myostatin expression…”
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The Mechanisms of Androgen Effects on Body Composition: Mesenchymal Pluripotent Cell as the Target of Androgen Action by Bhasin, Shalender, Taylor, Wayne E., Singh, Rajan, Artaza, Jorge, Sinha-Hikim, Indrani, Jasuja, Ravi, Choi, Helen, Gonzalez-Cadavid, Nestor F.

“…Testosterone supplementation increases muscle mass primarily by inducing muscle fiber hypertrophy; however, the mechanisms by which testosterone exerts its…”
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Zinc-Dependent Structure of a Single-Finger Domain of Yeast ADR1 by Párraga, Grace, Horvath, Suzanna J., Eisen, Arri, Taylor, Wayne E., Hood, Leroy, Young, Elton T., Klevit, Rachel E.

“…In the proposed ``zinc finger'' DNA-binding motif, each repeat unit binds a zinc metal ion through invariant Cys and His residues and this drives the folding…”
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Δ-4-Androstene-3,17-Dione Binds Androgen Receptor, Promotes Myogenesis in Vitro, and Increases Serum Testosterone Levels, Fat-Free Mass, and Muscle Strength in Hypogonadal Men by Jasuja, Ravi, Ramaraj, Pandurangan, Mac, Ricky Phong, Singh, Atam B., Storer, Thomas W., Artaza, Jorge, Miller, Aria, Singh, Rajan, Taylor, Wayne E., Lee, Martin L., Davidson, Tina, Sinha-Hikim, Indrani, Gonzalez-Cadavid, Nestor, Bhasin, Shalender

“…Previous studies of Δ4-androstene-3,17-dione (4-androstenedione) administration in men have not demonstrated sustained increments in testosterone levels,…”
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Didanosine-induced hepatitis by Ware, Athol J, Berggren, Ruth A, Taylor, Wayne E

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Didanosine-induced hepatitis by Ware, Athol J, Berggren, Ruth A, Taylor, Wayne E

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Alteration of gene expression profiles in skeletal muscle of rats exposed to microgravity during a spaceflight by Taylor, Wayne E, Bhasin, Shalender, Lalani, Rukhsana, Datta, Anuj, Gonzalez-Cadavid, Nestor F

“…To clarify the mechanism of skeletal muscle wasting during spaceflights, we investigated whether intramuscular gene expression profiles are affected, by using…”
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Expression of heterologous proteins in Saccharomyces cerevisiae using the ADH2 promoter by Price, V L, Taylor, W E, Clevenger, W, Worthington, M, Young, E T

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Stringent response in Escherichia coli induces expression of heat shock proteins by Grossman, A D, Taylor, W E, Burton, Z F, Burgess, R R, Gross, C A

“…The rpoD gene (encoding the 70,000 Mr sigma subunit of Escherichia coli RNA polymerase) is the most distal gene in an operon that contains three genes. The…”
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Designing Zinc-Finger ADR1 Mutants with Altered Specificity of DNA Binding to T in UAS1 Sequences by Taylor, Wayne E, Suruki, Hubert K, Lin, Amy Hsiu Ti, Naraghi-Arani, Pejman, Igarashi, Robert Y, Younessian, Maziar, Katkus, Pamela, Vo, Nam V

“…Yeast ADR1 contains two Cys2,His2 zinc fingers needed for DNA binding to the upstream activation sequence UAS1, with bases T5T6G7-G8A9G10 in the ADH2 promoter…”
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Testosterone Effects in Stimulating Cardiomyocyte Transcription Factor Expression in Murine Embryonic Stem Cell Differentiation by Preigo, Armando, Taylor, Wayne E

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Transcription from a heat-inducible promoter causes heat shock regulation of the sigma subunit of E. coli RNA polymerase by Taylor, W E, Straus, D B, Grossman, A D, Burton, Z F, Gross, C A, Burgess, R R

“…The rpoD gene encoding the sigma subunit of E. coli RNA polymerase is cotranscribed with rpsU and dnaG, encoding ribosomal protein S21 and DNA primase,…”
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