Search Results - "Taylor, Verdon"

Notch: an interactive player in neurogenesis and disease by Zhang, Runrui, Engler, Anna, Taylor, Verdon

“…Notch signaling is evolutionarily conserved from Drosophila to human. It plays critical roles in neural stem cell maintenance and neurogenesis in the embryonic…”
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Notch signaling as a master regulator of adult neurogenesis by Lampada, Aikaterini, Taylor, Verdon

“…Neurogenesis ceases in most regions of the mammalian brain before or shortly after birth, however, in a few restricted brain regions, the production of new…”
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Differential interactions between Notch and ID factors control neurogenesis by modulating Hes factor autoregulation by Boareto, Marcelo, Iber, Dagmar, Taylor, Verdon

“…During embryonic and adult neurogenesis, neural stem cells (NSCs) generate the correct number and types of neurons in a temporospatial fashion. Control of NSC…”
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Id4 Downstream of Notch2 Maintains Neural Stem Cell Quiescence in the Adult Hippocampus by Zhang, Runrui, Boareto, Marcelo, Engler, Anna, Louvi, Angeliki, Giachino, Claudio, Iber, Dagmar, Taylor, Verdon

“…Neural stem cells (NSCs) in the adult mouse hippocampal dentate gyrus (DG) are mostly quiescent, and only a few are in cell cycle at any point in time. DG NSCs…”
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Dynamic transcriptional programs define distinct mammalian cortical lineages by Mukhtar, Tanzila, Taylor, Verdon

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Oncogenic and Tumor-Suppressive Functions of NOTCH Signaling in Glioma by Parmigiani, Elena, Taylor, Verdon, Giachino, Claudio

“…Although the role of NOTCH signaling has been extensively studied in health and disease, many questions still remain unresolved. Being crucial for tissue…”
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Identification of self-replicating multipotent progenitors in the embryonic nervous system by high Notch activity and Hes5 expression by Basak, Onur, Taylor, Verdon

“…Discrimination of neural stem cells from other progenitors in the developing mammalian brain has been hampered by the lack of specific markers. Identifying the…”
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Spinal astrocytes in superficial laminae gate brainstem descending control of mechanosensory hypersensitivity by Kohro, Yuta, Matsuda, Tsuyoshi, Yoshihara, Kohei, Kohno, Keita, Koga, Keisuke, Katsuragi, Ryuichi, Oka, Takaaki, Tashima, Ryoichi, Muneta, Sho, Yamane, Takuya, Okada, Shota, Momokino, Kazuya, Furusho, Aogu, Hamase, Kenji, Oti, Takumi, Sakamoto, Hirotaka, Hayashida, Kenichiro, Kobayashi, Ryosuke, Horii, Takuro, Hatada, Izuho, Tozaki-Saitoh, Hidetoshi, Mikoshiba, Katsuhiko, Taylor, Verdon, Inoue, Kazuhide, Tsuda, Makoto

“…Astrocytes are critical regulators of CNS function and are proposed to be heterogeneous in the developing brain and spinal cord. Here we identify a population…”
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Striatal astrocytes produce neuroblasts in an excitotoxic model of Huntington's disease by Nato, Giulia, Caramello, Alessia, Trova, Sara, Avataneo, Valeria, Rolando, Chiara, Taylor, Verdon, Buffo, Annalisa, Peretto, Paolo, Luzzati, Federico

“…In the adult brain, subsets of astrocytic cells residing in well-defined neurogenic niches constitutively generate neurons throughout life. Brain lesions can…”
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Jagged1/Notch2 controls kidney fibrosis via Tfam-mediated metabolic reprogramming by Huang, Shizheng, Park, Jihwan, Qiu, Chengxiang, Chung, Ki Wung, Li, Szu-Yuan, Sirin, Yasemin, Han, Seung Hyeok, Taylor, Verdon, Zimber-Strobl, Ursula, Susztak, Katalin

“…While Notch signaling has been proposed to play a key role in fibrosis, the direct molecular pathways targeted by Notch signaling and the precise ligand and…”
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Notch2 Signaling Maintains NSC Quiescence in the Murine Ventricular-Subventricular Zone by Engler, Anna, Rolando, Chiara, Giachino, Claudio, Saotome, Ichiko, Erni, Andrea, Brien, Callum, Zhang, Runrui, Zimber-Strobl, Ursula, Radtke, Freddy, Artavanis-Tsakonas, Spyros, Louvi, Angeliki, Taylor, Verdon

“…Neurogenesis continues in the ventricular-subventricular zone (V-SVZ) of the adult forebrain from quiescent neural stem cells (NSCs). V-SVZ NSCs are a…”
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Fibrinogen induces neural stem cell differentiation into astrocytes in the subventricular zone via BMP signaling by Pous, Lauriane, Deshpande, Sachin S., Nath, Suvra, Mezey, Szilvia, Malik, Subash C., Schildge, Sebastian, Bohrer, Christian, Topp, Könül, Pfeifer, Dietmar, Fernández-Klett, Francisco, Doostkam, Soroush, Galanakis, Dennis K., Taylor, Verdon, Akassoglou, Katerina, Schachtrup, Christian

“…Neural stem/progenitor cells (NSPCs) originating from the subventricular zone (SVZ) contribute to brain repair during CNS disease. The microenvironment within…”
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A Tumor Suppressor Function for Notch Signaling in Forebrain Tumor Subtypes by Giachino, Claudio, Boulay, Jean-Louis, Ivanek, Robert, Alvarado, Alvaro, Tostado, Cristobal, Lugert, Sebastian, Tchorz, Jan, Coban, Mustafa, Mariani, Luigi, Bettler, Bernhard, Lathia, Justin, Frank, Stephan, Pfister, Stefan, Kool, Marcel, Taylor, Verdon

“…In the brain, Notch signaling maintains normal neural stem cells, but also brain cancer stem cells, indicating an oncogenic role. Here, we identify an…”
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Molecular Diversity Subdivides the Adult Forebrain Neural Stem Cell Population by Giachino, Claudio, Basak, Onur, Lugert, Sebastian, Knuckles, Philip, Obernier, Kirsten, Fiorelli, Roberto, Frank, Stephan, Raineteau, Olivier, Alvarez‐Buylla, Arturo, Taylor, Verdon

“…Neural stem cells (NSCs) in the ventricular domain of the subventricular zone (V‐SVZ) of rodents produce neurons throughout life while those in humans become…”
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Highly efficient baculovirus-mediated multigene delivery in primary cells by Mansouri, Maysam, Bellon-Echeverria, Itxaso, Rizk, Aurélien, Ehsaei, Zahra, Cianciolo Cosentino, Chiara, Silva, Catarina S., Xie, Ye, Boyce, Frederick M., Davis, M. Wayne, Neuhauss, Stephan C. F., Taylor, Verdon, Ballmer-Hofer, Kurt, Berger, Imre, Berger, Philipp

“…Multigene delivery and subsequent cellular expression is emerging as a key technology required in diverse research fields including, synthetic and structural…”
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Targeting neuronal lysosomal dysfunction caused by β-glucocerebrosidase deficiency with an enzyme-based brain shuttle construct by Gehrlein, Alexandra, Udayar, Vinod, Anastasi, Nadia, Morella, Martino L., Ruf, Iris, Brugger, Doris, von der Mark, Sophia, Thoma, Ralf, Rufer, Arne, Heer, Dominik, Pfahler, Nina, Jochner, Anton, Niewoehner, Jens, Wolf, Luise, Fueth, Matthias, Ebeling, Martin, Villaseñor, Roberto, Zhu, Yanping, Deen, Matthew C., Shan, Xiaoyang, Ehsaei, Zahra, Taylor, Verdon, Sidransky, Ellen, Vocadlo, David J., Freskgård, Per-Ola, Jagasia, Ravi

“…Mutations in glucocerebrosidase cause the lysosomal storage disorder Gaucher’s disease and are the most common risk factor for Parkinson’s disease. Therapies…”
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SAFB regulates hippocampal stem cell fate by targeting Drosha to destabilize Nfib mRNA by Forcella, Pascal, Ifflander, Niklas, Rolando, Chiara, Balta, Elli-Anna, Lampada, Aikaterini, Giachino, Claudio, Mukhtar, Tanzila, Bock, Thomas, Taylor, Verdon

“…Neural stem cells (NSCs) are multipotent and correct fate determination is crucial to guarantee brain formation and homeostasis. How NSCs are instructed to…”
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Early phenotypic asymmetry of sister oligodendrocyte progenitor cells after mitosis and its modulation by aging and extrinsic factors by Boda, Enrica, Di Maria, Silvia, Rosa, Patrizia, Taylor, Verdon, Abbracchio, Maria P., Buffo, Annalisa

“…Oligodendrocyte progenitor cells (OPCs) persist in the adult central nervous system and guarantee oligodendrocyte turnover throughout life. It remains obscure…”
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Endocardial to myocardial notch-wnt-bmp axis regulates early heart valve development by Wang, Yidong, Wu, Bingruo, Chamberlain, Alyssa A, Lui, Wendy, Koirala, Pratistha, Susztak, Katalin, Klein, Diana, Taylor, Verdon, Zhou, Bin

“…Endocardial to mesenchymal transformation (EMT) is a fundamental cellular process required for heart valve formation. Notch, Wnt and Bmp pathways are known to…”
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Expansion of human midbrain floor plate progenitors from induced pluripotent stem cells increases dopaminergic neuron differentiation potential by Fedele, Stefania, Collo, Ginetta, Behr, Katharina, Bischofberger, Josef, Müller, Stephan, Kunath, Tilo, Christensen, Klaus, Gündner, Anna Lisa, Graf, Martin, Jagasia, Ravi, Taylor, Verdon

“…Human induced pluripotent stem cells (hiPSCs) are invaluable to study developmental processes and disease mechanisms particularly in the brain. hiPSCs can be…”
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