Search Results - "Taylor, Steve M."
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1
Burden, pathology, and costs of malaria in pregnancy: new developments for an old problem
Published in The Lancet infectious diseases (01-04-2018)“…Over the past 10 years, knowledge of the burden, economic costs, and consequences of malaria in pregnancy has improved, and the prevalence of malaria caused by…”
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2
Haemoglobinopathies and the clinical epidemiology of malaria: a systematic review and meta-analysis
Published in The Lancet infectious diseases (01-06-2012)“…Summary Background Haemoglobinopathies can reduce the risk of malaria syndromes. We aimed to quantify the relation between different haemoglobin mutations and…”
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3
Sensitive DNA detection and SNP discrimination using ultrabright SERS nanorattles and magnetic beads for malaria diagnostics
Published in Biosensors & bioelectronics (15-07-2016)“…One of the major obstacles to implement nucleic acid-based molecular diagnostics at the point-of-care (POC) and in resource-limited settings is the lack of…”
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4
Effect of Plasmodium falciparum sulfadoxine-pyrimethamine resistance on the effectiveness of intermittent preventive therapy for malaria in pregnancy in Africa: a systematic review and meta-analysis
Published in The Lancet infectious diseases (01-05-2019)“…Resistance of Plasmodium falciparum to sulfadoxine-pyrimethamine threatens the antimalarial effectiveness of intermittent preventive treatment during pregnancy…”
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5
Hemoglobinopathies: slicing the Gordian knot of Plasmodium falciparum malaria pathogenesis
Published in PLoS pathogens (01-05-2013)“…Plasmodium falciparum malaria kills over 500,000 children every year and has been a scourge of humans for millennia. Owing to the co-evolution of humans and P…”
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Monthly sulfadoxine/pyrimethamine-amodiaquine or dihydroartemisinin-piperaquine as malaria chemoprevention in young Kenyan children with sickle cell anemia: A randomized controlled trial
Published in PLoS medicine (10-10-2022)“…Children with sickle cell anemia (SCA) in areas of Africa with endemic malaria transmission are commonly prescribed malaria chemoprevention. Chemoprevention…”
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7
Genotyping cognate Plasmodium falciparum in humans and mosquitoes to estimate onward transmission of asymptomatic infections
Published in Nature communications (10-02-2021)“…Malaria control may be enhanced by targeting reservoirs of Plasmodium falciparum transmission. One putative reservoir is asymptomatic malaria infections and…”
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Symptomatic malaria enhances protection from reinfection with homologous Plasmodium falciparum parasites
Published in PLoS pathogens (01-06-2023)“…A signature remains elusive of naturally-acquired immunity against Plasmodium falciparum. We identified P. falciparum in a 14-month cohort of 239 people in…”
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Absence of Putative Artemisinin Resistance Mutations Among Plasmodium falciparum in Sub-Saharan Africa: A Molecular Epidemiologic Study
Published in The Journal of infectious diseases (01-03-2015)“…Plasmodium falciparum parasites that are resistant to artemisinins have been detected in Southeast Asia. Resistance is associated with several polymorphisms in…”
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SARS-CoV-2 Cross-Reactivity in Prepandemic Serum from Rural Malaria-Infected Persons, Cambodia
Published in Emerging infectious diseases (01-05-2022)“…(1) that serum collected from malaria-infected persons in Cambodia before the coronavirus disease (COVID-19) pandemic harbored seroreactivity against severe…”
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Direct Detection of Unamplified Pathogen RNA in Blood Lysate using an Integrated Lab-in-a-Stick Device and Ultrabright SERS Nanorattles
Published in Scientific reports (06-03-2018)“…Direct detection of genetic biomarkers in body fluid lysate without target amplification will revolutionize nucleic acid-based diagnostics. However, the low…”
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12
Early malaria infection, dysregulation of angiogenesis, metabolism and inflammation across pregnancy, and risk of preterm birth in Malawi: A cohort study
Published in PLoS medicine (01-10-2019)“…Malaria in pregnancy is associated with adverse birth outcomes. However, the underlying mechanisms remain poorly understood. Tight regulation of angiogenic,…”
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13
Experience and confidence in health technologies: evidence from malaria testing and treatment in Western Kenya
Published in BMC public health (06-09-2022)“…Low adoption of effective health technologies increases illness morbidity and mortality worldwide. In the case of malaria, effective tools such as malaria…”
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14
Plasmodium falciparum infection in humans and mosquitoes influence natural Anopheline biting behavior and transmission
Published in Nature communications (30-05-2024)“…The human infectious reservoir of Plasmodium falciparum is governed by transmission efficiency during vector-human contact and mosquito biting preferences…”
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15
Scheduled Intermittent Screening with Rapid Diagnostic Tests and Treatment with Dihydroartemisinin-Piperaquine versus Intermittent Preventive Therapy with Sulfadoxine-Pyrimethamine for Malaria in Pregnancy in Malawi: An Open-Label Randomized Controlled Trial
Published in PLoS medicine (13-09-2016)“…In Africa, most plasmodium infections during pregnancy remain asymptomatic, yet are associated with maternal anemia and low birthweight. WHO recommends…”
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High-resolution micro-epidemiology of parasite spatial and temporal dynamics in a high malaria transmission setting in Kenya
Published in Nature communications (09-12-2019)“…Novel interventions that leverage the heterogeneity of parasite transmission are needed to achieve malaria elimination. To better understand spatial and…”
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Neurocognitive outcomes in Malawian children exposed to malaria during pregnancy: An observational birth cohort study
Published in PLoS medicine (28-09-2021)“…Annually 125 million pregnancies are at risk of malaria infection. However, the impact of exposure to malaria in pregnancy on neurodevelopment in children is…”
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bistro: An R package for vector bloodmeal identification by short tandem repeat overlap
Published in Methods in ecology and evolution (01-02-2024)“…Measuring vector–human contact in a natural setting can inform precise targeting of interventions to interrupt transmission of vector‐borne diseases. One…”
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19
High-Throughput Pooling and Real-Time PCR-Based Strategy for Malaria Detection
Published in Journal of Clinical Microbiology (01-02-2010)“…Molecular assays can provide critical information for malaria diagnosis, speciation, and drug resistance, but their cost and resource requirements limit their…”
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Born to sweet delight: Using natural models of malaria protection to understand and neutralize P. falciparum pathogenesis
Published in PLoS pathogens (01-06-2019)“…The human genome harbors archived responses to the pressure of severe, life-threatening malaria, and chief among these are innate variants of erythrocytes,…”
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