Search Results - "Taylor, Sarah E.B."

Hypoxia stimulates vesicular ATP release from rat osteoblasts by Orriss, Isabel R., Knight, Gillian E., Utting, Jennifer C., Taylor, Sarah E.B., Burnstock, Geoffrey, Arnett, Timothy R.

“…Many neuronal and non‐neuronal cell types release ATP in a controlled manner. After release, extracellular ATP (or, following hydrolysis, ADP) acts on cells in…”
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Hypothermia inhibits osteoblast differentiation and bone formation but stimulates osteoclastogenesis by Patel, Jessal J., Utting, Jennifer C., Key, Michelle L., Orriss, Isabel R., Taylor, Sarah E.B., Whatling, Philip, Arnett, Timothy R.

“…It has long been known that core body temperature declines with age, with temperatures of 35.5°C or below common in the elderly. However, the effects of…”
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Spatial transcriptomics at subspot resolution with BayesSpace by Zhao, Edward, Stone, Matthew R., Ren, Xing, Guenthoer, Jamie, Smythe, Kimberly S., Pulliam, Thomas, Williams, Stephen R., Uytingco, Cedric R., Taylor, Sarah E. B., Nghiem, Paul, Bielas, Jason H., Gottardo, Raphael

“…Recent spatial gene expression technologies enable comprehensive measurement of transcriptomic profiles while retaining spatial context. However, existing…”
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High resolution mapping of the tumor microenvironment using integrated single-cell, spatial and in situ analysis by Janesick, Amanda, Shelansky, Robert, Gottscho, Andrew D., Wagner, Florian, Williams, Stephen R., Rouault, Morgane, Beliakoff, Ghezal, Morrison, Carolyn A., Oliveira, Michelli F., Sicherman, Jordan T., Kohlway, Andrew, Abousoud, Jawad, Drennon, Tingsheng Yu, Mohabbat, Seayar H., Taylor, Sarah E. B.

“…Single-cell and spatial technologies that profile gene expression across a whole tissue are revolutionizing the resolution of molecular states in clinical…”
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Integrative multi-omics profiling in human decedents receiving pig heart xenografts by Schmauch, Eloi, Piening, Brian, Mohebnasab, Maedeh, Xia, Bo, Zhu, Chenchen, Stern, Jeffrey, Zhang, Weimin, Dowdell, Alexa K., Kim, Jacqueline I., Andrijevic, David, Khalil, Karen, Jaffe, Ian S., Loza, Bao-Li, Gragert, Loren, Camellato, Brendan R., Oliveira, Michelli F., O’Brien, Darragh P., Chen, Han M., Weldon, Elaina, Gao, Hui, Gandla, Divya, Chang, Andrew, Bhatt, Riyana, Gao, Sarah, Lin, Xiangping, Reddy, Kriyana P., Kagermazova, Larisa, Habara, Alawi H., Widawsky, Sophie, Liang, Feng-Xia, Sall, Joseph, Loupy, Alexandre, Heguy, Adriana, Taylor, Sarah E. B., Zhu, Yinan, Michael, Basil, Jiang, Lihua, Jian, Ruiqi, Chong, Anita S., Fairchild, Robert L., Linna-Kuosmanen, Suvi, Kaikkonen, Minna U., Tatapudi, Vasishta, Lorber, Marc, Ayares, David, Mangiola, Massimo, Narula, Navneet, Moazami, Nader, Pass, Harvey, Herati, Ramin S., Griesemer, Adam, Kellis, Manolis, Snyder, Michael P., Montgomery, Robert A., Boeke, Jef D., Keating, Brendan J.

“…In a previous study, heart xenografts from 10-gene-edited pigs transplanted into two human decedents did not show evidence of acute-onset cellular- or…”
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A Global Increase in 5‐Hydroxymethylcytosine Levels Marks Osteoarthritic Chondrocytes by Taylor, Sarah E. B., Smeriglio, Piera, Dhulipala, Lakshmi, Rath, Madhusikta, Bhutani, Nidhi

“…Objective To investigate the role of the newly discovered epigenetic mark 5‐hydroxymethylcytosine (5hmC) and its regulators in altered gene expression in…”
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Genome‐Wide Mapping of DNA Hydroxymethylation in Osteoarthritic Chondrocytes by Taylor, Sarah E. B., Li, Ye Henry, Wong, Wing H., Bhutani, Nidhi

“…Objective To examine the genome‐wide distribution of hydroxymethylated cytosine (5hmC) in osteoarthritic (OA) and normal chondrocytes in order to investigate…”
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Early induction of a prechondrogenic population allows efficient generation of stable chondrocytes from human induced pluripotent stem cells by Lee, Jieun, Taylor, Sarah E. B., Smeriglio, Piera, Lai, Janice, Maloney, William J., Yang, Fan, Bhutani, Nidhi

“…Regeneration of human cartilage is inherently inefficient; an abundant autologous source, such as human induced pluripotent stem cells (hiPSCs), is therefore…”
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Profiling the immune infiltrate in tumor samples at single cell resolution by Cheung, Denise, Adams, Bruce A., McDonnell, Wyatt J., Jaffe, David B., Puleo, Alaina R., Sukovich, David J, Reyes, Daniel J, Royall, Ariel J, Chi, Javelin C., Srinavas, Niranjan J, Krishnan, Sreenath J, Carli, Natasha J, Montesclaros, Luz J, Lau, Julia J, Stubbington, Michael J.T., Taylor, Sarah E.B.

“…Abstract Profiling the complex interactions of immune infiltrate with tumor cells in a tumor microenvironment is critical for advancing our understanding of…”
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Identification of Human Juvenile Chondrocyte-Specific Factors that Stimulate Stem Cell Growth by Taylor, Sarah E B, Lee, Jieun, Smeriglio, Piera, Razzaque, Adnan, Smith, Robert L, Dragoo, Jason L, Maloney, William J, Bhutani, Nidhi

“…Although regeneration of human cartilage is inherently inefficient, age is an important risk factor for osteoarthritis. Recent reports have provided compelling…”
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Rat osteoblast cultures by Orriss, Isabel R, Taylor, Sarah E B, Arnett, Timothy R

“…This chapter describes the isolation, culture and staining of primary osteoblasts from the calvaria and long bones of neonatal rats. The key advantages of this…”
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