Search Results - "Taylor, Penelope R.A."

Intracellular cytokine profiles by peripheral blood CD3+ T-cells in patients with classical Hodgkin lymphoma by Mainou-Fowler, Tryfonia, Taylor, Penelope R A, Miller, Sue, Dickinson, Anne M, Proctor, Stephen J

“…The intracellular profiles of T helper type 1 (Th1) and T helper type 2 (Th2) T-cell cytokines by peripheral blood (PB) CD3+ T-cells in patients with classical…”
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Impact of tumor Epstein-Barr virus status on presenting features and outcome in age-defined subgroups of patients with classic Hodgkin lymphoma: a population-based study by Jarrett, Ruth F., Stark, Gail L., White, Jo, Angus, Brian, Alexander, Freda E., Krajewski, Andrew S., Freeland, June, Taylor, G. Malcolm, Taylor, Penelope R.A.

“…The association between tumor Epstein-Barr virus (EBV) status and clinical outcome in Hodgkin lymphoma (HL) is controversial. This population-based study…”
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Clinically significant newly presenting autoimmune thrombocytopenic purpura in adults: a prospective study of a population‐based cohort of 245 patients by Neylon, Annette J., Saunders, Peter W. G., Howard, Martin R., Proctor, Stephen J., Taylor, Penelope R. A.

“…The true incidence and prognosis of autoimmune thrombocytopenic purpura (ITP) in adults is unknown. We present the results of a prospective study in a…”
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Interferon-γ and interleukin-6 gene polymorphisms associate with graft-versus-host disease in HLA-matched sibling bone marrow transplantation by Cavet, James, Dickinson, Anne M., Norden, Jean, Taylor, Penelope R.A., Jackson, Graham H., Middleton, Peter G.

“…Proinflammatory cytokines including interferon-γ (IFNγ), interleukin-6 (IL-6), and tumor necrosis factor-α (TNFα) are implicated in the pathogenesis of acute…”
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Cytokine Gene Polymorphisms Associating With Severe Acute Graft-Versus-Host Disease in HLA-Identical Sibling Transplants by Middleton, Peter G., Taylor, Penelope R.A., Jackson, Graham, Proctor, Stephen J., Dickinson, Anne M.

“…It is now well known that the initial phase of graft-versus-host disease (GVHD) involves cytokine release during preconditioning of the recipient of an…”
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Effect of IL‐6 promoter polymorphism on incidence and outcome in Hodgkin's lymphoma by Cordano, Pablo, Lake, Annette, Shield, Lesley, Taylor, G. M., Alexander, Freda E., Taylor, Penelope R. A., White, Jo, Jarrett, Ruth F.

“…Summary A single nucleotide polymorphism (SNP) is present at position ‐174 of the human interleukin‐6 gene. The risk of developing Hodgkin's lymphoma (HL) in…”
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Micro-vessel density and the expression of vascular endothelial growth factor (VEGF) and platelet-derived endothelial cell growth factor (PdEGF) in classical Hodgkin lymphoma (HL) by Mainou-Fowler, Tryfonia, Angus, Brian, Miller, Susan, Proctor, Stephen J., Taylor, Penelope R. A., Wood, Katrina M.

“…There is little information to date regarding the role of angiogenesis in Hodgkin lymphoma (HL). The present study examines micro-vessel density and the…”
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Phenotype and frequency of Epstein–Barr virus‐infected cells in pretreatment blood samples from patients with Hodgkin lymphoma by Khan, Gulfaraz, Lake, Annette, Shield, Lesley, Freeland, June, Andrew, Linda, Alexander, Freda E., Jackson, Robert, Taylor, Penelope R. A., McCruden, Elizabeth A. B., Jarrett, Ruth F.

“…Summary An accumulating body of data suggests that the Epstein–Barr virus (EBV), a lymphotropic herpesvirus, is involved in the pathogenesis of a proportion of…”
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Quantification improves the prognostic value of CD38 expression in B‐cell chronic lymphocytic leukaemia by Mainou‐Fowler, Tryfonia, Dignum, Helen, Taylor, Penelope R. A., Dickinson, Anne M., Saunders, Peter W. G., Proctor, Stephen J., Summerfield, Geoffrey P.

“…Recent studies have shown that CD38 expressed as a percentage of the antigen positivity can predict prognosis and disease progression in patients with B‐cell…”
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The dangers of iron overload in pyruvate kinase deficiency by Marshall, Scott R., Saunders, Peter W. G., Hamilton, Peter J., Taylor, Penelope R. A.

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High‐dose chlorambucil for the treatment of chronic lymphocytic leukaemia and low‐grade non‐Hodgkin's lymphoma by Summerfield, Geoffrey P., Taylor, Penelope R. A., Mounter, Philip J., Proctor, Stephen J.

“…Chlorambucil has been used for many years for the treatment of low‐grade B‐cell lymphoproliferative disorders, including chronic lymphocytic leukaemia and…”
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Acute myeloid leukaemia: Optimising treatment in elderly patients by JACKSON, Graham H, TAYLOR, Penelope R. A

“…Acute myeloid leukaemia (AML) is a disease of the elderly (median age at presentation 64 years). The outcome in older patients with AML is much worse than that…”
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Predicting graft-versus-host disease in HLA-identical bone marrow transplants : A comparison of T-cell frequency analysis and a human skin explant model by DICKINSON, A. M, SVILAND, L, WANG, X. N, JACKSON, G, TAYLOR, P. R. A, DUNN, A, PROCTOR, S. J

“…Graft-versus-host disease (GVHD) occurring after HLA-identical sibling bone marrow transplantation (BMT) is considered to be mainly caused by minor…”
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T-cell frequency analysis does not predict the incidence of graft-versus-host disease in HLA-matched sibling bone marrow transplantation by XIAONONG WANG, TAYLOR, P. R. A, SKINNER, R, JACKSON, G. H, PROCTOR, S. J, HEDLEY, D, DICKINSON, A. M

“…Graft-versus-host disease (GVHD) is a major and sometimes fatal complication of allogeneic bone marrow transplantation (BMT). The prediction of GVHD remains an…”
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Survival in Young Patients (Less than 40 Years) with Follicular Lymphoma: A population Based Study by the Scotland and Newcastle Lymphoma Group by Summerfield, Geoffrey P, Wood, Katrina M, Taylor, Penelope RA, White, Josephine M, Mounter, Philip J, Proctor, Stephen J

“…We have examined in a population-based observational study the survival of young patients (less than 40 years) with follicular lymphoma (FL) treated…”
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Tumour Necrosis Factor Gene Polymorphisms in Lymphoproliferative Disease by Mainou-Fowler, Tryfonia, Dickinson, Anne M., Taylor, Penelope R.A., Mounter, Philip, Jack, Fergus, Proctor, Steven J., Nordon, Jean, Middleton, Peter G.

“…Tumour necrosis factor (TNF) α is involved in the pathogenesis of established lymphoproliferative disease. Serum levels of TNFα and its soluble receptors are…”
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Early High Dose Chemotherapy Intensification with Autologous Bone Marrow Transplantation in Lymphoma Associated with Retention of Fertility and Normal Pregnancies in Females by Jackson, Graham H., Wood, Angela, Taylor, Penelope R. A., Lennard, Anne L., Lucraft, Helen, Heppleston, Andrew, Robinson, Pamela, Moore, Jean, Proctor, Stephen J.

“…As more centres consider autologous bone marrow and peripheral blood stem cell transplantation for patients with high risk Hodgkin's disease (HD) and…”
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Cytokine gene polymorphisms associating with severe acute graft-versus-host disease in HLA-identical sibling transplants by MIDDLETON, P. G, TAYLOR, P. R. A, JACKSON, G, PROCTOR, S. J, DICKINSON, A. M

“…It is now well known that the initial phase of graft-versus-host disease (GVHD) involves cytokine release during preconditioning of the recipient of an…”
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Primary treatment of low-grade non-Hodgkin's lymphoma using an all oral anthracycline-containing regimen, chlorambucil, idarubicin, dexamethasone (CID) : a phase II study by TAYLOR, P. R. A, JACKSON, G. H, GALLOWAY, M. J, SOUKOP, M, TINEGATE, H, ANGUS, B, PROCTOR, S. J

“…The majority of patients with low-grade non-Hodgkin's lymphoma (LGNHL) are in the older age groups and are thus less able to tolerate aggressive treatment…”
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Acute lymphoblastic leukaemia in the elderly by Taylor, P R, Reid, M M, Proctor, S J

“…Acute lymphoblastic leukaemia (ALL) is rare in adults over the age of 60 years, with an incidence of 1 per 100,000 per year. We review the current (sparse)…”
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