Search Results - "Taylor, Nicholas J."

Registration and primary outcome reporting in behavioral health trials by Taylor, Nicholas J, Gorman, Dennis M

“…Registration of research studies is designed to lock investigators into a data collection and analysis plan before a study starts and thereby limit their…”
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Deciphering hierarchical features in the energy landscape of adenylate kinase folding/unfolding by Taylor, J Nicholas, Pirchi, Menahem, Haran, Gilad, Komatsuzaki, Tamiki

“…Hierarchical features of the energy landscape of the folding/unfolding behavior of adenylate kinase, including its dependence on denaturant concentration, are…”
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Raman imaging of rat nonalcoholic fatty liver tissues reveals distinct biomolecular states by Helal, Khalifa Mohammad, Cahyadi, Harsono, Taylor, J. Nicholas, Okajima, Akira, Tabata, Koji, Kumamoto, Yasuaki, Mochizuki, Kentaro, Itoh, Yoshito, Takamatsu, Tetsuro, Tanaka, Hideo, Fujita, Katsumasa, Komatsuzaki, Tamiki, Harada, Yoshinori

“…An essential challenge in diagnosing states of nonalcoholic fatty liver disease (NAFLD) is the early prediction of progression from nonalcoholic fatty liver…”
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Ammonia and the neutrophil in the pathogenesis of hepatic encephalopathy in cirrhosis by Shawcross, Debbie L., Shabbir, Shabnam S., Taylor, Nicholas J., Hughes, Robin D.

“…Hepatic encephalopathy (HE) constitutes a neuropsychiatric syndrome which remains a major clinical problem in patients with cirrhosis. In the severest form of…”
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Lipid droplet accumulation and adipophilin expression in follicular thyroid carcinoma by Hayakawa, Michiyo, Taylor, J. Nicholas, Nakao, Ryuta, Mochizuki, Kentaro, Sawai, Yuki, Hashimoto, Kosuke, Tabata, Koji, Kumamoto, Yasuaki, Fujita, Katsumasa, Konishi, Eiichi, Hirano, Shigeru, Tanaka, Hideo, Komatsuzaki, Tamiki, Harada, Yoshinori

“…Follicular neoplasms of the thyroid include follicular thyroid carcinoma (FTC) and follicular thyroid adenoma (FTA). However, the differences in cytological…”
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Metabolomics of primary cutaneous melanoma and matched adjacent extratumoral microenvironment by Taylor, Nicholas J, Gaynanova, Irina, Eschrich, Steven A, Welsh, Eric A, Garrett, Timothy J, Beecher, Chris, Sharma, Ritin, Koomen, John M, Smalley, Keiran S M, Messina, Jane L, Kanetsky, Peter A

“…Melanoma causes the vast majority of deaths attributable to skin cancer, largely due to its propensity for metastasis. To date, few studies have examined…”
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Circulating neutrophil dysfunction in acute liver failure by Taylor, Nicholas J., Nishtala, Anirudh, Manakkat Vijay, Godhev K., Abeles, R. Daniel, Auzinger, Georg, Bernal, William, Ma, Yun, Wendon, Julia A., Shawcross, Debbie L.

“…Systemic inflammation and susceptibility to developing sepsis is common in acute liver failure (ALF) resulting in tissue damage and organ failure. This study…”
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Catalytic Decarboxylative Alkenylation of Enolates by Schröder, Sybrin P, Taylor, Nicholas J, Jackson, Paula, Franckevičius, Vilius

“…A palladium-catalyzed decarboxylative alkenylation of stabilized enolates has been developed, which gives rise to alkenylated dicarbonyl products from enol…”
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Rapid Quantification of Microvessels of Three-Dimensional Blood–Brain Barrier Model Using Optical Coherence Tomography and Deep Learning Algorithm by Zhang, Huiting, Kang, Dong-Hee, Piantino, Marie, Tominaga, Daisuke, Fujimura, Takashi, Nakatani, Noriyuki, Taylor, J. Nicholas, Furihata, Tomomi, Matsusaki, Michiya, Fujita, Satoshi

“…The blood–brain barrier (BBB) is a selective barrier that controls the transport between the blood and neural tissue features and maintains brain homeostasis…”
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Neutrophil Toll-Like Receptor 9 Expression and the Systemic Inflammatory Response in Acetaminophen-Induced Acute Liver Failure by Manakkat Vijay, Godhev K, Ryan, Jennifer M, Abeles, Robin D, Ramage, Stephen, Patel, Vishal, Bernsmeier, Christine, Riva, Antonio, McPhail, Mark J W, Tranah, Thomas H, Markwick, Lee J L, Taylor, Nicholas J, Bernal, William, Auzinger, Georg, Willars, Chris, Chokshi, Shilpa, Wendon, Julia A, Ma, Yun, Shawcross, Debbie L

“…OBJECTIVES:There is a marked propensity for patients with acetaminophen-induced acute liver failure to develop sepsis, which may culminate in multiple organ…”
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Synthesis, Crystal Structures, Linear and Nonlinear Optical Properties, and Theoretical Studies of (p-R-Phenyl)-, (p-R-Phenylethynyl)-, and (E)-[2-(p-R-Phenyl)ethenyl]dimesitylboranes and Related Compounds by Yuan, Zheng, Entwistle, Christopher D., Collings, Jonathan C., Albesa-Jové, David, Batsanov, Andrei S., Howard, Judith A. K., Taylor, Nicholas J., Kaiser, Hanns Martin, Kaufmann, Dieter E., Poon, Suk-Yue, Wong, Wai-Yeung, Jardin, Christophe, Fathallah, Sofiane, Boucekkine, Abdou, Halet, Jean-François, Marder, Todd B.

“…The (p‐R‐phenyl)dimesitylboranes (R=Me2N, MeO, MeS, Br, I), (p‐R‐phenylethynyl)dimesitylboranes (R=Me2N, MeO, MeS, H),…”
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Inherited variation at MC1R and histological characteristics of primary melanoma by Taylor, Nicholas J, Busam, Klaus J, From, Lynn, Groben, Pamela A, Anton-Culver, Hoda, Cust, Anne E, Begg, Colin B, Dwyer, Terence, Gallagher, Richard P, Gruber, Stephen B, Orlow, Irene, Rosso, Stefano, Thomas, Nancy E, Zanetti, Roberto, Rebbeck, Timothy R, Berwick, Marianne, Kanetsky, Peter A

“…Variation in the melanocortin-1receptor (MC1R) gene is associated with pigmentary phenotypes and risk of malignant melanoma. Few studies have reported on MC1R…”
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70 years of JSFA by Taylor, Nicholas J

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A General Copper-Mediated Nucleophilic 18F Fluorination of Arenes by Tredwell, Matthew, Preshlock, Sean M., Taylor, Nicholas J., Gruber, Stefan, Huiban, Mickael, Passchier, Jan, Mercier, Joël, Génicot, Christophe, Gouverneur, Véronique

“…Molecules labeled with fluorine‐18 are used as radiotracers for positron emission tomography. An important challenge is the labeling of arenes not amenable to…”
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Classification of food spoilage bacterial species and their sodium chloride, sodium acetate and glycine tolerance using chemometrics analysis and Raman spectroscopy by Yamamoto, Takashi, Taylor, J. Nicholas, Koseki, Shige, Koyama, Kento

“…The purpose is classification of stress tolerances of spoilage bacteria using Raman spectra and chemometrics. We obtained Raman spectra of six spoilage…”
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High-Resolution Raman Microscopic Detection of Follicular Thyroid Cancer Cells with Unsupervised Machine Learning by Taylor, J. Nicholas, Mochizuki, Kentaro, Hashimoto, Kosuke, Kumamoto, Yasuaki, Harada, Yoshinori, Fujita, Katsumasa, Komatsuzaki, Tamiki

“…We use Raman microscopic images with high spatial and spectral resolution to investigate differences between human follicular thyroid (Nthy-ori 3-1) and…”
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Isobutene Polymerization Using a Chelating Diborane Co-Initiator by Lewis, Stewart P, Taylor, Nicholas J, Piers, Warren E, Collins, Scott

“…Lewis acidic diborane 1 (J. Am. Chem. Soc. 1999, 121, 3244−3245) is highly effective for both proton- and cationogen-initiated isobutene polymerization in…”
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Total Synthesis of Isoprekinamycin:  Structural Evidence for Enhanced Diazonium Ion Character and Growth Inhibitory Activity toward Cancer Cells by Liu, Wei, Buck, Matthew, Chen, Nan, Shang, Muhong, Taylor, Nicholas J, Asoud, Jalil, Wu, Xing, Hasinoff, Brian B, Dmitrienko, Gary I

“…The structurally novel diazobenzo[a]fluorene antibiotic isoprekinamycin (IPK) has been synthesized for the first time employing a Suzuki coupling of a…”
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Linear and Nonlinear Optical Properties of Three-Coordinate Organoboron Compounds by Yuan, Zheng, Collings, Jonathan C., Taylor, Nicholas J., Marder, Todd B., Jardin, Christophe, Halet, Jean-François

“…Three-coordinate boron, isoelectronic with a trigonal planar carbonium ion, possesses a vacant p orbital which can conjugate with an organic π system and thus…”
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(−)-Sparteine-Mediated Directed ortho-Metalation of N-Cumyl-N-ethylferrocenecarboxamide. Versatile Routes to Functionalized Planar Chiral Ferrocenecarboxamides, Amines, Esters and Phosphines by Metallinos, Costa, Szillat, Hauke, Taylor, Nicholas J., Snieckus, Victor

“…N‐Cumyl‐N‐ethylferrocenecarboxamide 5 provides planar chiral carboxamides 6 in high yield and % ee via (−)‐sparteine‐mediated directed ortho‐metalation. Mild…”
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