Search Results - "Taylor, Joann"
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Photoreceptor oxidative stress in hyperoxia-induced proliferative retinopathy accelerates rd8 degeneration
Published in PloS one (03-07-2017)“…To investigate the impact of photoreceptor oxidative stress on photoreceptor degeneration in mice carrying the rd8 mutation (C57BL/6N). We compared the…”
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Hyperoxia-Induced Proliferative Retinopathy: Early Interruption of Retinal Vascular Development with Severe and Irreversible Neurovascular Disruption
Published in PloS one (18-11-2016)“…Bronchopulmonary dysplasia (BPD) is a major cause of neonatal morbidity in premature infants, occurring as a result of arrested lung development combined with…”
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3
Mouse lung development and NOX1 induction during hyperoxia are developmentally regulated and mitochondrial ROS dependent
Published in American journal of physiology. Lung cellular and molecular physiology (15-08-2015)“…Animal models demonstrate that exposure to supraphysiological oxygen during the neonatal period compromises both lung and pulmonary vascular development,…”
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4
Aberrant cGMP signaling persists during recovery in mice with oxygen-induced pulmonary hypertension
Published in PloS one (09-08-2017)“…Bronchopulmonary dysplasia (BPD), a common complication of preterm birth, is associated with pulmonary hypertension (PH) in 25% of infants with moderate to…”
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5
SOD2 activity is not impacted by hyperoxia in murine neonatal pulmonary artery smooth muscle cells and mice
Published in International journal of molecular sciences (19-03-2015)“…Pulmonary hypertension (PH) complicates bronchopulmonary dysplasia (BPD) in 25% of infants. Superoxide dismutase 2 (SOD2) is an endogenous mitochondrial…”
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Selective depletion of vascular EC-SOD augments chronic hypoxic pulmonary hypertension
Published in American journal of physiology. Lung cellular and molecular physiology (01-12-2014)“…Excess superoxide has been implicated in pulmonary hypertension (PH). We previously found lung overexpression of the antioxidant extracellular superoxide…”
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7
Heat-killed Trypanosoma cruzi induces acute cardiac damage and polyantigenic autoimmunity
Published in PloS one (21-01-2011)“…Chagas heart disease, caused by the protozoan parasite Trypanosoma cruzi, is a potentially fatal cardiomyopathy often associated with cardiac autoimmunity. T…”
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8
Neonatal Extracellular Superoxide Dismutase Knockout Mice Increase Total Superoxide Dismutase Activity and VEGF Expression after Chronic Hyperoxia
Published in Antioxidants (01-08-2021)“…Bronchopulmonary dysplasia (BPD) is a common lung disease affecting premature infants that develops after exposure to supplemental oxygen and reactive oxygen…”
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Right ventricular cyclic nucleotide signaling is decreased in hyperoxia-induced pulmonary hypertension in neonatal mice
Published in American journal of physiology. Heart and circulatory physiology (15-06-2015)“…Pulmonary hypertension (PH) and right ventricular hypertrophy (RVH) affect 25-35% of premature infants with significant bronchopulmonary dysplasia (BPD),…”
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10
Disrupted pulmonary artery cyclic guanosine monophosphate signaling in mice with hyperoxia-induced pulmonary hypertension
Published in American journal of respiratory cell and molecular biology (01-02-2014)“…Pulmonary hypertension (PH) occurs in 25 to 35% of premature infants with significant bronchopulmonary dysplasia (BPD). Neonatal mice exposed to 14 days of…”
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11
The HIV Env Variant N283 Enhances Macrophage Tropism and Is Associated with Brain Infection and Dementia
Published in Proceedings of the National Academy of Sciences - PNAS (10-10-2006)“…HIV infects tissue macrophages and brain microglia, which express lower levels of CD4 and CCR5 than CD4⁺ T cells in peripheral blood. Mechanisms that enhance…”
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12
Alternative entry receptors for herpes simplex virus and their roles in disease
Published in Cell host & microbe (12-07-2007)“…Either herpesvirus entry mediator (HVEM, TNFRSF14) or nectin-1 (PVRL1) is sufficient for herpes simplex virus (HSV) infection of cultured cells. The…”
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13
Dose-dependent effects of glucocorticoids on pulmonary vascular development in a murine model of hyperoxic lung injury
Published in Pediatric research (01-05-2016)“…Background: Exposure of neonatal mice to hyperoxia results in pulmonary vascular remodeling and aberrant phosphodiesterase type 5 (PDE5) signaling. Although…”
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14
Trypanosoma brucei Acyl-Protein Thioesterase-like (TbAPT-L) Is a Lipase with Esterase Activity for Short and Medium-Chain Fatty Acids but Has No Depalmitoylation Activity
Published in Pathogens (Basel) (27-10-2022)“…Dynamic post-translational modifications allow the rapid, specific, and tunable regulation of protein functions in eukaryotic cells. -acylation is the only…”
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Functional interaction between herpes simplex virus type 2 gD and HVEM transiently dampens local chemokine production after murine mucosal infection
Published in PloS one (24-01-2011)“…Herpes virus entry mediator (HVEM) is one of two principal receptors mediating herpes simplex virus (HSV) entry into murine and human cells. It functions…”
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16
Depletion of regulatory T cells decreases cardiac parasitosis and inflammation in experimental Chagas disease
Published in Parasitology research (1987) (01-03-2015)“…Infection with the protozoan parasite Trypanosoma cruzi may lead to a potentially fatal cardiomyopathy known as Chagas heart disease. This disease is…”
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17
Cell Cycle Inhibition To Treat Sleeping Sickness
Published in mBio (19-09-2017)“…African trypanosomiasis is caused by infection with the protozoan parasite During infection, this pathogen divides rapidly to high density in the bloodstream…”
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Calflagin Inhibition Prolongs Host Survival and Suppresses Parasitemia in Trypanosoma brucei Infection
Published in Eukaryotic Cell (01-06-2010)“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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19
Sildenafil attenuates vaso-obliteration and neovascularization in a mouse model of retinopathy of prematurity
Published in Investigative ophthalmology & visual science (10-03-2014)“…We sought to determine the effect of sildenafil on retinal vascular changes in a mouse model of oxygen-induced retinopathy (OIR). Vascular defects in OIR mice…”
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20
Macrophage entry mediated by HIV Envs from brain and lymphoid tissues is determined by the capacity to use low CD4 levels and overall efficiency of fusion
Published in Virology (New York, N.Y.) (30-03-2007)“…Abstract HIV infects macrophages and microglia in the central nervous system (CNS), which express lower levels of CD4 than CD4+ T cells in peripheral blood. To…”
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