Search Results - "Taylor, Jeremy M.G"
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Gene expression signatures for predicting prognosis of squamous cell and adenocarcinomas of the lung
Published in Cancer research (Chicago, Ill.) (01-08-2006)“…Non-small-cell lung cancers (NSCLC) compose 80% of all lung carcinomas with squamous cell carcinomas (SCC) and adenocarcinoma representing the majority of…”
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2
Gene-expression profiles predict survival of patients with lung adenocarcinoma
Published in Nature medicine (01-08-2002)“…Histopathology is insufficient to predict disease progression and clinical outcome in lung adenocarcinoma. Here we show that gene-expression profiles based on…”
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3
Subgroup identification from randomized clinical trial data
Published in Statistics in medicine (30-10-2011)“…We consider the problem of identifying a subgroup of patients who may have an enhanced treatment effect in a randomized clinical trial, and it is desirable…”
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4
Score Test for Conditional Independence Between Longitudinal Outcome and Time to Event Given the Classes in the Joint Latent Class Model
Published in Biometrics (01-03-2010)“…Latent class models have been recently developed for the joint analysis of a longitudinal quantitative outcome and a time to event. These models assume that…”
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Criteria for the use of omics-based predictors in clinical trials
Published in Nature (London) (17-10-2013)“…A checklist of criteria to determine the readiness of high-throughput ‘omics’-based tests for guiding patient therapy in clinical trials is discussed; the…”
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Gene expression-based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study
Published in Nature medicine (01-08-2008)“…Studies of gene expression in lung cancer have the potential to affect patient care, but the general applicability of the derived classifiers is unclear. David…”
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Validation of Biomarker-Based Risk Prediction Models
Published in Clinical cancer research (01-10-2008)“…The increasing availability and use of predictive models to facilitate informed decision making highlights the need for careful assessment of the validity of…”
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Interleukin‐6 predicts recurrence and survival among head and neck cancer patients
Published in Cancer (15-08-2008)“…BACKGROUND. Increased pretreatment serum interleukin (IL)‐6 levels among patients with head and neck squamous cell carcinoma (HNSCC) have been shown to…”
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EGFR, p16, HPV Titer, Bcl-xL and p53, Sex, and Smoking As Indicators of Response to Therapy and Survival in Oropharyngeal Cancer
Published in Journal of clinical oncology (01-07-2008)“…To prospectively identify markers of response to therapy and outcome in an organ-sparing trial for advanced oropharyngeal cancer. Pretreatment biopsies were…”
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10
Dopamine D2/D3 imbalance during migraine attack and allodynia in vivo
Published in Neurology (25-04-2017)“…OBJECTIVE:To evaluate in vivo the dynamics of endogenous dopamine (DA) neurotransmission during migraine ictus with allodynia. METHODS:We examined 8 episodic…”
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Confirmation of a Low α/β Ratio for Prostate Cancer Treated by External Beam Radiation Therapy Alone Using a Post-Treatment Repeated-Measures Model for PSA Dynamics
Published in International journal of radiation oncology, biology, physics (2011)“…Purpose To estimate the α/β ratio of prostate cancer treated with external beam radiation only by use of a model of long-term prostate-specific antigen (PSA)…”
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Semiparametric Modeling of Longitudinal Measurements and Time-to-Event Data-A Two-Stage Regression Calibration Approach
Published in Biometrics (01-12-2008)“…In this article we investigate regression calibration methods to jointly model longitudinal and survival data using a semiparametric longitudinal model and a…”
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13
Redefining Perineural Invasion: Integration of Biology With Clinical Outcome
Published in Neoplasia (New York, N.Y.) (01-07-2018)“…A diagnosis of perineural invasion (PNI), defined as cancer within or surrounding at least 33% of the nerve, leads to selection of aggressive treatment in…”
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14
On the detection and refinement of transcription factor binding sites using ChIP-Seq data
Published in Nucleic acids research (01-04-2010)“…Coupling chromatin immunoprecipitation (ChIP) with recently developed massively parallel sequencing technologies has enabled genome-wide detection of…”
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15
Chemoselection As a Strategy for Organ Preservation in Advanced Oropharynx Cancer: Response and Survival Positively Associated With HPV16 Copy Number
Published in Journal of clinical oncology (01-07-2008)“…To test induction chemotherapy (IC) followed by concurrent chemoradiotherapy (CRT) or surgery/radiotherapy (RT) for advanced oropharyngeal cancer and to assess…”
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The impact of dose on parotid salivary recovery in head and neck cancer patients treated with radiation therapy
Published in International journal of radiation oncology, biology, physics (01-03-2007)“…Purpose: A common side effect experienced by head and neck cancer patients after radiation therapy (RT) is impairment of the parotid glands’ ability to produce…”
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Bayesian Approach to Surrogacy Assessment Using Principal Stratification in Clinical Trials
Published in Biometrics (01-06-2010)“…A surrogate marker (S) is a variable that can be measured earlier and often more easily than the true endpoint (T) in a clinical trial. Most previous research…”
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Use of Individual Fraction Size Data from 3756 Patients to Directly Determine the α/β Ratio of Prostate Cancer
Published in International journal of radiation oncology, biology, physics (01-05-2007)“…Purpose To examine the effect of fraction size and total dose of radiation on recurrence of localized prostate cancer. Methods and Materials A total of 3756…”
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Outcomes evaluation of a weekly nurse practitioner-managed symptom management clinic for patients with head and neck cancer treated with chemoradiotherapy
Published in Oncology nursing forum (01-11-2013)“…To determine whether improved monitoring through close follow-up with a nurse practitioner (NP) could enhance treatment compliance and decrease frequency of…”
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Discordant Protein and mRNA Expression in Lung Adenocarcinomas
Published in Molecular & cellular proteomics (01-04-2002)“…The relationship between gene expression measured at the mRNA level and the corresponding protein level is not well characterized in human cancer. In this…”
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