Search Results - "Taylor, Frederick R."

CGRP, Amylin, Immunology, and Headache Medicine by Taylor, Frederick R.

“…Background Calcitonin gene‐related peptide (CGRP) therapeutics introduce new excitement and possibly yet to be determined distressing discords in the field of…”
Get full text

Nutraceuticals and Headache: The Biological Basis by Taylor, Frederick R.

“…Nutrition must affect the structure and functioning of the brain. Since the brain has very high metabolic activity, what we consume throughout the day is…”
Get full text

CDP7657, an anti-CD40L antibody lacking an Fc domain, inhibits CD40L-dependent immune responses without thrombotic complications: an in vivo study by Shock, Anthony, Burkly, Linda, Wakefield, Ian, Peters, Christopher, Garber, Ellen, Ferrant, Janine, Taylor, Frederick R, Su, Lihe, Hsu, Yen-Ming, Hutto, David, Amirkhosravi, Ali, Meyer, Todd, Francis, John, Malcolm, Sarah, Robinson, Martyn, Brown, Derek, Shaw, Stevan, Foulkes, Roland, Lawson, Alastair, Harari, Olivier, Bourne, Timothy, Maloney, Alison, Weir, Neil

“…CD40 ligand (CD40L) blockade has demonstrated efficacy in experimental autoimmune models. However, clinical trials of hu5c8, an anti-human CD40L IgG1 antibody,…”
Get full text

Anti‐BDCA2 monoclonal antibody inhibits plasmacytoid dendritic cell activation through Fc‐dependent and Fc‐independent mechanisms by Pellerin, Alex, Otero, Karel, Czerkowicz, Julie M, Kerns, Hannah M, Shapiro, Renée I, Ranger, Ann M, Otipoby, Kevin L, Taylor, Frederick R, Cameron, Thomas O, Viney, Joanne L, Rabah, Dania

“…Type I interferons (IFN‐I) are implicated in the pathogenesis of systemic lupus erythematosus (SLE). In SLE, immune complexes bind to the CD32a (FcγRIIa)…”
Get full text

Intrathecal injection of adenosine 2A receptor agonists reversed neuropathic allodynia through protein kinase (PK)A/PKC signaling by Loram, Lisa C, Taylor, Frederick R, Strand, Keith A, Harrison, Jacqueline A, RzasaLynn, Rachael, Sholar, Paige, Rieger, Jayson, Maier, Steven F, Watkins, Linda R

“…Highlight • Intrathecal A2A R agonist induced long duration reversal of mechanical allodynia in a variety of neuropathic models…”
Get full text

Prior exposure to glucocorticoids potentiates lipopolysaccharide induced mechanical allodynia and spinal neuroinflammation by Loram, Lisa C, Taylor, Frederick R, Strand, Keith A, Frank, Matthew G, Sholar, Paige, Harrison, Jacqueline A, Maier, Steven F, Watkins, Linda R

“…Highlight ► Prior corticosterone potentiates the inflammatory cytokine release and allodynia induced by intrathecal lipopolysaccharide…”
Get full text

Weight change associated with the use of migraine-preventive medications by Taylor, Frederick R., MD, FAHS

“…Abstract Background: Medications administered long term, such as those used for migraine prophylaxis, are often associated with weight change as a side effect…”
Get full text

The morphogen Sonic hedgehog is an indirect angiogenic agent upregulating two families of angiogenic growth factors by Isner, Jeffrey M, Pola, Roberto, Ling, Leona E, Silver, Marcy, Corbley, Michael J, Kearney, Marianne, Blake Pepinsky, R, Shapiro, Renee, Taylor, Frederick R, Baker, Darren P, Asahara, Takayuki

“…Sonic hedgehog (Shh) is a prototypical morphogen known to regulate epithelial/mesenchymal interactions during embryonic development. We found that the…”
Get full text

Systemic administration of an alpha-7 nicotinic acetylcholine agonist reverses neuropathic pain in male Sprague Dawley rats by Loram, Lisa C, Taylor, Frederick R, Strand, Keith A, Maier, Steven F, Speake, Jason D, Jordan, Kristen G, James, John W, Wene, Steven P, Pritchard, Robert C, Green, Heather, Van Dyke, Katherine, Mazarov, Anatoly, Letchworth, Sharon R, Watkins, Linda R

“…Alpha-7 nicotinic acetylcholine receptor (α7 nAChR) agonists attenuate pain and inflammation in preclinical models. This study tested whether systemic delivery…”
Get more information

Tobacco, Nicotine, and Headache by Taylor, Frederick R.

“…Background Migraineurs variably attribute the cause of their headache to tobacco exposure, whereas tobacco is often stated to cause headache‐related disability…”
Get full text

Intrathecal injection of an alpha seven nicotinic acetylcholine receptor agonist attenuates gp120-induced mechanical allodynia and spinal pro-inflammatory cytokine profiles in rats by Loram, Lisa C, Harrison, Jacqueline A, Chao, Lindsey, Taylor, Frederick R, Reddy, Anireddy, Travis, Carissa L, Giffard, Rona, Al-Abed, Yousef, Tracey, Kevin, Maier, Steven F, Watkins, Linda R

“…Abstract Nicotinic acetylcholine receptors (nAchRs) are not only key receptors in the autonomic nervous system, but also are present on immune cells. The alpha…”
Get full text

Antigens and Antibodies in Disease With Specifics About CGRP Immunology by Taylor, Frederick R.

“…Growth in knowledge about calcitonin gene‐related peptide (CGRP) in the pathophysiology of migraine brought CGRP antagonism to headache medicine. Failures in…”
Get full text

Prior laparotomy or corticosterone potentiates lipopolysaccharide-induced fever and sickness behaviors by Hains, Leah E, Loram, Lisa C, Taylor, Frederick R, Strand, Keith A, Wieseler, Julie L, Barrientos, Ruth M, Young, Jennifer J, Frank, Matthew G, Sobesky, Julia, Martin, Thomas J, Eisenach, James C, Maier, Steven F, Johnson, John D, Fleshner, Monika, Watkins, Linda R

“…Abstract Stimulating sensitized immune cells with a subsequent immune challenge results in potentiated pro-inflammatory responses translating into exacerbated…”
Get full text

Abstracts and Citations by Taylor, Frederick R., Cooper, Wade, Kaniecki, Robert G.

Get full text

Abstracts and Citations by Cooper, Wade, Kaniecki, Robert G., Taylor, Frederick R.

Get full text

Abstracts and Citations by Taylor, Frederick R., Cooper, Wade, Kaniecki, Robert G.

Get full text

Conditional Disruption of Hedgehog Signaling Pathway Defines its Critical Role in Hair Development and Regeneration by Wang, Li Chun, Liu, Zhong-Ying, Shapiro, Renee, Yang, Jianliang, Sizing, Irene, Rayhorn, Paul, Garber, Ellen A., Benjamin, Chris D., Williams, Kevin P., Taylor, Frederick R., Ling, Leona, Burkly, Linda C., Gambardella, Laure, Delacour, Alexandra, Barrandon, Yann

“…Members of the vertebrate hedgehog family (Sonic, Indian, and Desert) have been shown to be essential for the development of various organ systems, including…”
Get full text

Abstracts and Citations by Taylor, Frederick R., Cooper, Wade, Kaniecki, Robert G.

Get full text

Enhanced Potency of Human Sonic Hedgehog by Hydrophobic Modification by Taylor, Frederick R, Wen, Dingyi, Garber, Ellen A, Carmillo, Amie N, Baker, Darren P, Arduini, Robert M, Williams, Kevin P, Weinreb, Paul H, Rayhorn, Paul, Hronowski, Xiaoping, Whitty, Adrian, Day, Eric S, Boriack-Sjodin, Ann, Shapiro, Renee I, Galdes, Alphonse, Pepinsky, R. Blake

“…Post-translational modifications of the developmental signaling protein Sonic hedgehog (Shh) by a long-chain fatty acid at the N-terminus and cholesterol at…”
Get full text

Abstracts and Citations by Kaniecki, Robert G., Taylor, Frederick R., Cooper, Wade M.

Get full text