Search Results - "Taylor, Carla G."

Growth State-Dependent Activation of eNOS in Response to DHA: Involvement of p38 MAPK by Huang, Shiqi, Taylor, Carla G, Zahradka, Peter

“…Our laboratory previously reported that docosahexaenoic acid (DHA) differentially activates p38 mitogen-activated protein kinase (MAPK) in growing and…”
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Long Chain N3-PUFA Decreases ACE2 Protein Levels and Prevents SARS-CoV-2 Cell Entry by Huang, Shiqi, Taylor, Carla G, Zahradka, Peter

“…Angiotensin-converting enzyme 2 (ACE2) is a target of interest for both COVID-19 and cardiovascular disease management. Even though lower ACE2 levels may be…”
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Marginal Zinc Deficiency Promotes Pancreatic Islet Enlargement While Zinc Supplementation Improves the Pancreatic Insulin Response in Zucker Diabetic Fatty Rats by Rech, Leslie, Zahradka, Peter, Taylor, Carla G

“…Zinc deficiency has been associated with the worsening of diabetes while zinc supplementation has been proposed to ameliorate diabetes. This study examined the…”
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Differential Modulation by Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA) of Mesenteric Fat and Macrophages and T Cells in Adipose Tissue of Obese fa / fa Zucker Rats by Hong, Lena, Zahradka, Peter, Taylor, Carla G

“…Polyunsaturated fatty acids (PUFAs) can alter adipose tissue function; however, the relative effects of plant and marine n3-PUFAs are less clear. Our objective…”
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CAMKK2 regulates mitochondrial function by controlling succinate dehydrogenase expression, post-translational modification, megacomplex assembly, and activity in a cell-type-specific manner by Sabbir, Mohammad Golam, Taylor, Carla G, Zahradka, Peter

“…The calcium (Ca2+)/calmodulin (CAM)-activated kinase kinase 2 (CAMKK2)-signaling regulates several physiological processes, for example, glucose metabolism and…”
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Dietary Docosahexaenoic Acid (DHA) and Eicosapentaenoic Acid (EPA) Operate by Different Mechanisms to Modulate Hepatic Steatosis and Hyperinsulemia in fa/fa Zucker Rats by Hong, Lena, Zahradka, Peter, Cordero-Monroy, Luis, Wright, Brenda, Taylor, Carla G

“…Hepatic steatosis, an early stage of non-alcoholic fatty liver disease, is commonly present in obesity and type 2 diabetes, and is associated with reduced…”
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Rebelling against the (Insulin) Resistance: A Review of the Proposed Insulin-Sensitizing Actions of Soybeans, Chickpeas, and Their Bioactive Compounds by Clark, Jaime L, Taylor, Carla G, Zahradka, Peter

“…Insulin resistance is a major risk factor for diseases such as type 2 diabetes and metabolic syndrome. Current methods for management of insulin resistance…”
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Distinct effects of α-linolenic acid and docosahexaenoic acid on the expression of genes related to cholesterol metabolism and the response to infection in THP-1 monocytes and immune cells of obese humans by Rodway, Lisa A., Pauls, Samantha D., Pascoe, Christopher D., Aukema, Harold M., Taylor, Carla G., Zahradka, Peter

“…Monocytes play a large role in chronic inflammatory conditions such as obesity, atherosclerosis and infection. Marine-derived omega-3 fatty acids such as…”
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Establishing the interchangeability of arterial stiffness but not endothelial function parameters in healthy individuals by Perrault, Raissa, Omelchenko, Alexander, Taylor, Carla G, Zahradka, Peter

“…Development of instruments capable of detecting early stage vascular disease has increased interest in employing arterial stiffness (e.g. pulse wave velocity…”
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Zinc, the pancreas, and diabetes: insights from rodent studies and future directions by Taylor, Carla G

“…Molecular and cellular studies have demonstrated several roles for zinc (Zn) in insulin production and the consequent actions of insulin on metabolism…”
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Importance of extracellular matrix and growth state for the EA.hy926 endothelial cell response to polyunsaturated fatty acids by Du, Youjia, Taylor, Carla G, Aukema, Harold M, Zahradka, Peter

“…Consumption of different PUFAs (polyunsaturated fatty acids) can induce functional changes in blood vessels via endothelial cells, which interact with dietary…”
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Thrombin-Mediated Formation of Globular Adiponectin Promotes an Increase in Adipose Tissue Mass by Zahradka, Peter, Taylor, Carla G, Tworek, Leslee, Perrault, Raissa, M'Seffar, Sofia, Murali, Megha, Loader, Tara, Wigle, Jeffrey T

“…A decrease in the circulating levels of adiponectin in obesity increases the risk of metabolic complications, but the role of globular adiponectin, a truncated…”
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Regular Black Bean Consumption Is Necessary to Sustain Improvements in Small-Artery Vascular Compliance in the Spontaneously Hypertensive Rat by Clark, Jaime L, Loader, Tara B, Anderson, Hope D, Zahradka, Peter, Taylor, Carla G

“…Edible legume seeds, such as lentils, have been shown to modulate the structural and functional properties of hypertensive blood vessels, however, the effects…”
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Exploring the Cardio-metabolic Relevance of T-cadherin: A Pleiotropic Adiponectin Receptor by Clark, Jaime L, Taylor, Carla G, Zahradka, Peter

“…T-cadherin is a unique member of the cadherin family and is primarily expressed in the cardiovascular system. T-cadherin has not been abundantly studied, but…”
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Canola oil rich in oleic acid improves diastolic heart function in diet-induced obese rats by Thandapilly, Sijo Joseph, Raj, Pema, Louis, Xavier Lieben, Perera, Danielle, Yamanagedara, Prasanga, Zahradka, Peter, Taylor, Carla G, Netticadan, Thomas

“…Obesity is a leading cause of cardiovascular disease. It directly affects heart structure and function and contributes to heart failure. Diet is a major factor…”
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Protein source in a high‐protein diet modulates reductions in insulin resistance and hepatic steatosis in fa/fa Zucker rats by Wojcik, Jennifer L., Devassy, Jessay G., Wu, Yinghong, Zahradka, Peter, Taylor, Carla G., Aukema, Harold M.

“…Objective High‐protein diets are being promoted to reduce insulin resistance and hepatic steatosis in metabolic syndrome. Therefore, the effect of protein…”
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Effects of Diets Enriched with Conventional or High-Oleic Canola Oils on Vascular Endothelial Function: A Sub-Study of the Canola Oil Multi-Centre Intervention Trial 2 (COMIT-2), a Randomized Crossover Controlled Feeding Study by Davis, Kristin M, Petersen, Kristina S, Bowen, Kate J, Jones, Peter J H, Taylor, Carla G, Zahradka, Peter, Letourneau, Karen, Perera, Danielle, Wilson, Angela, Wagner, Paul R, Kris-Etherton, Penny M, West, Sheila G

“…Partial replacement of saturated fatty acids (SFA) with unsaturated fatty acids is recommended to reduce cardiovascular disease (CVD) risk. Monounsaturated…”
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Adipokines and the cardiovascular system: mechanisms mediating health and disease by Northcott, Josette M, Yeganeh, Azadeh, Taylor, Carla G, Zahradka, Peter, Wigle, Jeffrey T

“…This review focuses on the role of adipokines in the maintenance of a healthy cardiovascular system, and the mechanisms by which these factors mediate the…”
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Activation of phosphatidylinositol-3 kinase, AMP-activated kinase and Akt substrate-160 kDa by trans-10, cis-12 conjugated linoleic acid mediates skeletal muscle glucose uptake by Mohankumar, Suresh K, Taylor, Carla G, Siemens, Linda, Zahradka, Peter

“…Conjugated linoleic acid (CLA), a dietary lipid, has been proposed as an antidiabetic agent. However, studies specifically addressing the molecular dynamics of…”
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Variations in Adipokine Genes AdipoQ, Lep, and LepR Are Associated with Risk for Obesity-Related Metabolic Disease: The Modulatory Role of Gene-Nutrient Interactions by Enns, Jennifer Emily, Zahradka, Peter, Taylor, Carla G.

“…Obesity rates are rapidly increasing worldwide and facilitate the development of many related disease states, such as cardiovascular disease, the metabolic…”
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