Search Results - "Taylor, Barbara E"

Behavioral Phenotyping and Pathological Indicators of Parkinson's Disease in C. elegans Models by Maulik, Malabika, Mitra, Swarup, Bult-Ito, Abel, Taylor, Barbara E, Vayndorf, Elena M

“…Parkinson's disease (PD) is a neurodegenerative disorder with symptoms that progressively worsen with age. Pathologically, PD is characterized by the…”
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Genetic Silencing of Fatty Acid Desaturases Modulates α-Synuclein Toxicity and Neuronal Loss in Parkinson-Like Models of C. elegans by Maulik, Malabika, Mitra, Swarup, Basmayor, Ajiel Mae, Lu, Brianna, Taylor, Barbara E, Bult-Ito, Abel

“…The molecular basis of Parkinson's disease (PD) is currently unknown. There is increasing evidence that fat metabolism is at the crossroad of key molecular…”
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Complex interaction of dietary fat and Alaskan bog blueberry supplementation influences manganese mediated neurotoxicity and behavioral impairments by Maulik, Malabika, Mitra, Swarup, Sweeney, McKenzie, Lu, Brianna, Taylor, Barbara E., Bult-Ito, Abel

“…[Display omitted] •Alaskan blueberries ameliorate metal-induced neurotoxicity.•Diet interactions modulate rescue of behavioral deficits by Alaskan…”
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BUILDing BLaST: promoting rural students' biomedical research careers using a culturally responsive, one health approach by Taylor, Barbara E, Reynolds, Arleigh J, Etz, Kathy E, MacCalla, Nicole M G, Cotter, Paul A, DeRuyter, Tiffany L, Hueffer, Karsten

“…Most postsecondary institutions in the state of Alaska (USA) have a broad mission to serve diverse students, many of whom come from schools in rural villages…”
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Sir-2.1 mediated attenuation of α-synuclein expression by Alaskan bog blueberry polyphenols in a transgenic model of Caenorhabditis elegans by Maulik, Malabika, Mitra, Swarup, Hunter, Skyler, Hunstiger, Moriah, Oliver, S. Ryan, Bult-Ito, Abel, Taylor, Barbara E.

“…Misfolding and accumulation of cellular protein aggregates are pathological hallmarks of aging and neurodegeneration. One such protein is α-synuclein, which…”
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The rostral medulla of bullfrog tadpoles contains critical lung rhythmogenic and chemosensitive regions across metamorphosis by Reed, Mitchell D., Iceman, Kimberly E., Harris, Michael B., Taylor, Barbara E.

“…The development of amphibian breathing provides insight into vertebrate respiratory control mechanisms. Neural oscillators in the rostral and caudal medulla…”
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Development of central respiratory control in anurans: The role of neurochemicals in the emergence of air-breathing and the hypoxic response by Janes, Tara A., Rousseau, Jean-Philippe, Fournier, Stéphanie, Kiernan, Elizabeth A., Harris, Michael B., Taylor, Barbara E., Kinkead, Richard

“…•Amphibians transition from aquatic to aerial breathing during metamorphosis.•Diverse neurochemicals orchestrate development of respiratory control…”
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Governance as leadership: reframing the work of nonprofit boards by Chait, Richard P, Ryan, William P, Taylor, Barbara E

“…A new framework for helping nonprofit organizations maximize the effectiveness of their boards. Written by noted consultants and researchers attuned to the…”
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Caenorhabditis Sieve: A Low-tech Instrument and Methodology for Sorting Small Multicellular Organisms by Hunter, Skyler, Maulik, Malabika, Scerbak, Courtney, Vayndorf, Elena, Taylor, Barbara E

“…Caenorhabditis elegans (C. elegans) is a well-established model organism used across a range of basic and biomedical research. Within the nematode research…”
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Buccal rhythmogenesis and CO2 sensitivity in Lithobates catesbeianus tadpole brainstems across metamorphosis by Reed, Mitchell D., Iceman, Kimberly E., Harris, Michael B., Taylor, Barbara E

“…•The midbrain/pons affects buccal burst shape and CO2 responsiveness in bullfrog tadpoles.•Buccal bursting can be responsive to elevated CO2, but only when the…”
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Mechanosensory Neuron Aging: Differential Trajectories with Lifespan-Extending Alaskan Berry and Fungal Treatments in Caenorhabditis elegans by Scerbak, Courtney, Vayndorf, Elena M, Hernandez, Alicia, McGill, Colin, Taylor, Barbara E

“…Many nutritional interventions that increase lifespan are also proposed to postpone age-related declines in motor and cognitive function. Potential sources of…”
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Catastrophic Reproductive Failure, Terrestrial Survival, and Persistence of the Marbled Salamander by TAYLOR, BARBARA E., SCOTT, DAVID E., GIBBONS, J. WHITFIELD

“…Wide variation in reproductive success is common among amphibians that breed in seasonal ponds, but persistence of adults can buffer against these…”
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CO2 -inhibited neurons in the medullary raphé are GABAergic by Iceman, Kimberly E, Corcoran, Andrea E, Taylor, Barbara E, Harris, Michael B

“…Highlights • The medullary raphé contains neurons that are reversibly inhibited by CO2. • CO2 -inhibited raphé cells synthesize GABA, but not serotonin. • Fast…”
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Chronic, but not acute, ethanol exposure impairs central hypercapnic ventilatory drive in bullfrog tadpoles by Taylor, Barbara E, Brundage, Cord M

“…Highlights ► Central hypercapnia response of early tadpoles lost after 10-wk ethanol exposure. ► Central hypercapnia response of late tadpoles lost after 10-wk…”
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Response of Aquatic Invertebrates to Ecological Rehabilitation of Southeastern USA Depressional Wetlands by Batzer, Darold P., Taylor, Barbara E., DeBiase, Adrienne E., Brantley, Susan E., Schultheis, Richard

“…We assessed aquatic invertebrate response to ecological rehabilitation treatment in 20 depression wetlands on the Savannah River Site, South Carolina, USA. All…”
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Intermittent hypercapnia enhances CO2 responsiveness and overcomes serotonergic dysfunction by Mosher, Bryan P, Taylor, Barbara E, Harris, Michael B

“…Highlights • We confirm that chemoresponsiveness depends on ketanserin-sensitive 5-HT mechanisms. • Intermittent hypercapnia pretreatment maintains…”
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Chronic nicotine and ethanol exposure both disrupt central ventilatory responses to hypoxia in bullfrog tadpoles by Taylor, Barbara E, Brundage, Cord M, McLane, Lisa H

“…Highlights • The control of breathing network within the bullfrog brainstem is sensitive to hypoxia. • The central response to hypoxia is an active suppression…”
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Neuroplasticity of the central hypercapnic ventilatory response: Teratogen‐induced impairment and subsequent recovery during development by Brundage, Cord M., Taylor, Barbara E.

“…Neuroventilation is highly plastic and exposure to either of two distinct teratogens, nicotine or ethanol, during development results in a similar loss of the…”
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Insulin signaling in the aging of healthy and proteotoxically stressed mechanosensory neurons by Scerbak, Courtney, Vayndorf, Elena M, Parker, J Alex, Neri, Christian, Driscoll, Monica, Taylor, Barbara E

“…Insulin signaling is central to cellular metabolism and organismal aging. However, the role of insulin signaling in natural and proteotoxically stressed aging…”
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Timing and duration of developmental nicotine exposure contribute to attenuation of the tadpole hypercapnic neuroventilatory response by Brundage, Cord M., Taylor, Barbara E.

“…The ability for air‐breathing vertebrates to adjust ventilation in response to increased CO2 (hypercapnia) is fundamental to maintaining pH homeostasis…”
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