Search Results - "Taylor, Austin"
-
1
IL33 (Interleukin 33)/ST2 (Interleukin 1 Receptor-Like 1) Axis Drives Protective Microglial Responses and Promotes White Matter Integrity After Stroke
Published in Stroke (1970) (01-06-2021)“…Emerging evidence highlights the importance of IL33 (interleukin 33) and its receptor (ST2 [interleukin 1 receptor-like 1]) in normal brains and neurological…”
Get full text
Journal Article -
2
Islet prohormone processing in health and disease
Published in Diabetes, obesity & metabolism (01-09-2018)“…Biosynthesis of peptide hormones by pancreatic islet endocrine cells is a tightly orchestrated process that is critical for metabolic homeostasis. Like…”
Get full text
Journal Article -
3
MR-Conditional SMA-Based Origami Joint
Published in IEEE/ASME transactions on mechatronics (01-04-2019)“…Foldable origami structures have been implemented into robotics as a way of compacting joints and circuitry into smaller structures. This technique is…”
Get full text
Journal Article -
4
The β Cell in Diabetes: Integrating Biomarkers With Functional Measures
Published in Endocrine reviews (01-10-2021)“…Abstract The pathogenesis of hyperglycemia observed in most forms of diabetes is intimately tied to the islet β cell. Impairments in propeptide processing and…”
Get full text
Journal Article Web Resource -
5
Microbial metabolite sensor GPR43 controls severity of experimental GVHD
Published in Nature communications (10-09-2018)“…Microbiome-derived metabolites influence intestinal homeostasis and regulate graft-versus-host disease (GVHD), but the molecular mechanisms remain unknown…”
Get full text
Journal Article -
6
A prognostic score for acute graft-versus-host disease based on biomarkers: a multicentre study
Published in The Lancet. Haematology (2015)“…Summary Background Graft-versus-host disease (GVHD) is the major cause of non-relapse mortality after allogeneic haemopoietic stem-cell transplantation (SCT)…”
Get full text
Journal Article -
7
Extent and context dependence of pleiotropy revealed by high-throughput single-cell phenotyping
Published in PLoS biology (17-08-2020)“…Pleiotropy-when a single mutation affects multiple traits-is a controversial topic with far-reaching implications. Pleiotropy plays a central role in debates…”
Get full text
Journal Article -
8
Deletion of Carboxypeptidase E in β-Cells Disrupts Proinsulin Processing but Does Not Lead to Spontaneous Development of Diabetes in Mice
Published in Diabetes (New York, N.Y.) (01-09-2023)“…Carboxypeptidase E (CPE) facilitates the conversion of prohormones into mature hormones and is highly expressed in multiple neuroendocrine tissues. Carriers of…”
Get full text
Journal Article -
9
ZLN005, a PGC-1α Activator, Protects the Liver against Ischemia-Reperfusion Injury and the Progression of Hepatic Metastases
Published in Cells (Basel, Switzerland) (29-08-2024)“…Exercise can promote sustainable protection against cold and warm liver ischemia-reperfusion injury (IRI) and tumor metastases. We have shown that this…”
Get full text
Journal Article -
10
Islet amyloid polypeptide does not suppress pancreatic cancer
Published in Molecular metabolism (Germany) (01-02-2023)“…Pancreatic cancer risk is elevated approximately two-fold in type 1 and type 2 diabetes. Islet amyloid polypeptide (IAPP) is an abundant beta-cell peptide…”
Get full text
Journal Article -
11
Peptide-Guided Nanoparticle Drug Delivery for Cardiomyocytes
Published in Biology (Basel, Switzerland) (01-01-2024)“…Nanoparticles (NPs) have been extensively utilized as a drug delivery system to control the release of therapeutic agents to treat cardiac injuries. However,…”
Get full text
Journal Article -
12
Origami Lesion-Targeting Device for CT-Guided Interventions
Published in Journal of imaging (23-01-2019)“…The objective of this study is to preliminarily evaluate a lesion-targeting device for CT-guided interventions. The device is created by laser cutting the…”
Get full text
Journal Article -
13
Eczema Varicella/Zoster (Varicellicum)
Published in Clinical pediatrics (01-06-2017)Get full text
Journal Article -
14
Modular force approximating soft robotic pneumatic actuator
Published in International journal for computer assisted radiology and surgery (01-11-2018)“…Purpose Soft robots are highly flexible and adaptable instruments that have proven extremely useful, especially in the surgical environment where compliance…”
Get full text
Journal Article -
15
Underwater video reveals decreased activity of rocky intertidal snails during high tides and cooler days
Published in Marine ecology (Berlin, West) (01-04-2017)“…Nearly all of our understanding of rocky inter‐tidal ecology comes from studies conducted at low tide. To study inter‐tidal organisms at high tide, we anchored…”
Get full text
Journal Article -
16
A spatiotemporal proteomic map of human adipogenesis
Published in Nature metabolism (2024)“…White adipocytes function as major energy reservoirs in humans by storing substantial amounts of triglycerides, and their dysfunction is associated with…”
Get full text
Journal Article -
17
A Comprehensive Lifestyle Randomized Clinical Trial: Design and Initial Patient Experience
Published in Integrative cancer therapies (01-03-2017)“…Background: Although epidemiological research demonstrates that there is an association between lifestyle factors and risk of breast cancer recurrence,…”
Get full text
Journal Article -
18
3382 Assessing Racial Disparities in Hepatitis C Retention of Care
Published in Journal of clinical and translational science (01-03-2019)“…OBJECTIVES/SPECIFIC AIMS: The objective of this study is to assess differences in outcomes between African Americans (AAs) and whites along the HCV care…”
Get full text
Journal Article -
19
An Algorithm Combining Clinical Characteristics and Day 7 Biomarker Concentrations Predicts Future Graft-Versus-Host Disease Following Related Donor Hematopoietic Cell Transplantation
Published in Blood (16-11-2012)“…Abstract ▪463▪This icon denotes a clinically relevant abstract We have recently described an algorithm combining biomarkers and clinical characteristics, such…”
Get full text
Journal Article -
20
Structure and DNA-binding properties of the cytolysin regulator CylR2 from Enterococcus faecalis
Published in The EMBO journal (15-09-2004)“…Enterococcus faecalis is one of the major causes for hospital‐acquired antibiotic‐resistant infections. It produces an exotoxin, called cytolysin, which is…”
Get full text
Journal Article