Search Results - "Taylor, Anna M W"

Sex differences in learned conditioned pain sensitivity by Dworsky-Fried, Zoë, Taylor, Anna M. W.

“…A unique paradigm to investigate the intersection between memory, pain, and stress reveals new details about the processes that underlie pain memory. In both…”
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Reducing Astrocyte Calcium Signaling In Vivo Alters Striatal Microcircuits and Causes Repetitive Behavior by Yu, Xinzhu, Taylor, Anna M.W., Nagai, Jun, Golshani, Peyman, Evans, Christopher J., Coppola, Giovanni, Khakh, Baljit S.

“…Astrocytes tile the central nervous system, but their functions in neural microcircuits in vivo and their roles in mammalian behavior remain incompletely…”
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Microglia disrupt mesolimbic reward circuitry in chronic pain by Taylor, Anna M W, Castonguay, Annie, Taylor, Alison J, Murphy, Niall P, Ghogha, Atefeh, Cook, Christopher, Xue, Lihua, Olmstead, Mary C, De Koninck, Yves, Evans, Christopher J, Cahill, Catherine M

“…Chronic pain attenuates midbrain dopamine (DA) transmission, as evidenced by a decrease in opioid-evoked DA release in the ventral striatum, suggesting that…”
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Kappa Opioid Receptors Drive a Tonic Aversive Component of Chronic Pain by Liu, Shiwei Steve, Pickens, Sarah, Burma, Nicole E, Ibarra-Lecue, Ines, Yang, Hongyan, Xue, Lihua, Cook, Chris, Hakimian, Joshua K, Severino, Amie L, Lueptow, Lindsay, Komarek, Kristina, Taylor, Anna M W, Olmstead, Mary C, Carroll, F Ivy, Bass, Caroline E, Andrews, Anne M, Walwyn, Wendy, Trang, Tuan, Evans, Christopher J, Leslie, Frances M, Cahill, Catherine M

“…Pain is a multidimensional experience and negative affect, or how much the pain is "bothersome", significantly impacts the sufferers' quality of life. It is…”
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Neuroimmune Regulation of GABAergic Neurons Within the Ventral Tegmental Area During Withdrawal from Chronic Morphine by Taylor, Anna M W, Castonguay, Annie, Ghogha, Atefeh, Vayssiere, Pia, Pradhan, Amynah A A, Xue, Lihua, Mehrabani, Sadaf, Wu, Juli, Levitt, Pat, Olmstead, Mary C, De Koninck, Yves, Evans, Christopher J, Cahill, Catherine M

“…Opioid dependence is accompanied by neuroplastic changes in reward circuitry leading to a negative affective state contributing to addictive behaviors and risk…”
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Topography of microglial activation in sensory‐ and affect‐related brain regions in chronic pain by Taylor, Anna M.W., Mehrabani, Sadaf, Liu, Steve, Taylor, Alison J., Cahill, Catherine M.

“…Microglial activation in the spinal cord plays a central role in the development and maintenance of chronic pain after a peripheral nerve injury (PNI). There…”
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Multiple Sclerosis and the Endogenous Opioid System by Dworsky-Fried, Zoë, Chadwick, Caylin I., Kerr, Bradley J., Taylor, Anna M. W.

“…Multiple sclerosis (MS) is an autoimmune disease characterized by chronic inflammation, neuronal degeneration and demyelinating lesions within the central…”
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Does the kappa opioid receptor system contribute to pain aversion? by Cahill, Catherine M, Taylor, Anna M W, Cook, Christopher, Ong, Edmund, Morón, Jose A, Evans, Christopher J

“…The kappa opioid receptor (KOR) and the endogenous peptide-ligand dynorphin have received significant attention due the involvement in mediating a variety of…”
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Consequences of the ablation of nonpeptidergic afferents in an animal model of trigeminal neuropathic pain by Taylor, Anna M.W., Osikowicz, Maria, Ribeiro-da-Silva, Alfredo

“…Ablation of nonpeptidergic nociceptive afferents exacerbated the nociceptive responses following a neuropathic lesion, suggesting a complex role in the…”
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Mesolimbic dopamine signaling in acute and chronic pain: implications for motivation, analgesia, and addiction by Taylor, Anna M.W., Becker, Susanne, Schweinhardt, Petra, Cahill, Catherine

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Editorial: Modulation of Reward Circuitry by Pain and Stress by Taylor, Anna M W, Cahill, Catherine M

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Behavioural and Morphological Evidence for the Involvement of Glial Cell Activation in Delta Opioid Receptor Function: Implications for the Development of Opioid Tolerance by Holdridge, Sarah V, Armstrong, Stacey A, Taylor, Anna MW, Cahill, Catherine M

“…Previous studies have demonstrated that prolonged morphine treatment in vivo induces the translocation of delta opioid receptors (δORs) from intracellular…”
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GDNF levels in the lower lip skin in a rat model of trigeminal neuropathic pain: Implications for nonpeptidergic fiber reinnervation and parasympathetic sprouting by Taylor, Anna M.W., Ribeiro-da-Silva, Alfredo

“…Trigeminal neuropathic pain is associated with trigeminal nerve damage. Significant remodeling of the peripheral nervous system may contribute to the pain;…”
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The gut microbiota mediates reward and sensory responses associated with regimen-selective morphine dependence by Lee, Kevin, Vuong, Helen E, Nusbaum, David J, Hsiao, Elaine Y, Evans, Christopher J, Taylor, Anna M W

“…Opioid use for long-term pain management is limited by adverse side effects, such as hyperalgesia and negative affect. Neuroinflammation in the brain and…”
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Preclinical evidence for the use of the atypical antipsychotic, brexpiprazole, for opioid use disorder by Nickols, Julia E.R., Dursun, Serdar M., Taylor, Anna M.W.

“…Opioid addiction is characterized by adaptations in the mesolimbic dopamine system that occur during chronic opioid use. Alterations in dopaminergic…”
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Corticolimbic circuitry in the modulation of chronic pain and substance abuse by Taylor, Anna M.W.

“…The transition from acute to chronic pain is accompanied by increased engagement of emotional and motivational circuits. Adaptations within this corticolimbic…”
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Allostatic Mechanisms of Opioid Tolerance Beyond Desensitization and Downregulation by Cahill, Catherine M, Walwyn, Wendy, Taylor, Anna M.W, Pradhan, Amynah A.A, Evans, Christopher J

“…Mechanisms of opioid tolerance have focused on adaptive modifications within cells containing opioid receptors, defined here as cellular allostasis,…”
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Pain, Motivation, Migraine, and the Microbiome: New Frontiers for Opioid Systems and Disease by Parker, Kyle E., Sugiarto, Elizabeth, Taylor, Anna M.W., Pradhan, Amynah A., Al-Hasani, Ream

“…For decades the broad role of opioids in addiction, neuropsychiatric disorders, and pain states has been somewhat well established. However, in recent years,…”
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Central amygdala inflammation drives pain hypersensitivity and attenuates morphine analgesia in experimental autoimmune encephalomyelitis by Dworsky-Fried, Zoë, Faig, Christian A., Vogel, Holly A., Kerr, Bradley J., Taylor, Anna M.W.

“…Chronic pain is a highly prevalent symptom associated with the autoimmune disorder multiple sclerosis (MS). The central nucleus of the amygdala plays a…”
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Sex differences in kappa opioid receptor antinociception is influenced by the number of X chromosomes in mouse by Taylor, Anna M. W., Chadwick, Caylin I., Mehrabani, Sadaf, Hrncir, Haley, Arnold, Arthur P., Evans, Christopher J.

“…Kappa opioid receptor (KOR) agonists produce robust analgesia with minimal abuse liability and are considered promising pharmacological agents to manage…”
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